7 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMARCAD1	Uncharacterized protein. (1099 aa)
	F6U2S4_MONDO	Deacetylase sirtuin-type domain-containing protein. (261 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa)
	ELK4	ETS transcription factor ELK4. (432 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (713 aa)
	SIRT7	Sirtuin 7. (521 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6U2S4_MONDO	SIRT1	ENSMODP00000038370	ENSMODP00000021523	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.566
HDAC1	HDAC2	ENSMODP00000021783	ENSMODP00000022264	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
HDAC1	SIRT1	ENSMODP00000021783	ENSMODP00000021523	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Deacetylase sirtuin-type domain-containing protein.	0.602
HDAC1	SIRT7	ENSMODP00000021783	ENSMODP00000003748	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sirtuin 7.	0.436
HDAC2	HDAC1	ENSMODP00000022264	ENSMODP00000021783	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
HDAC2	SIRT1	ENSMODP00000022264	ENSMODP00000021523	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Deacetylase sirtuin-type domain-containing protein.	0.602
HDAC2	SIRT7	ENSMODP00000022264	ENSMODP00000003748	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sirtuin 7.	0.436
SIRT1	F6U2S4_MONDO	ENSMODP00000021523	ENSMODP00000038370	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.566
SIRT1	HDAC1	ENSMODP00000021523	ENSMODP00000021783	Deacetylase sirtuin-type domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.602
SIRT1	HDAC2	ENSMODP00000021523	ENSMODP00000022264	Deacetylase sirtuin-type domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.602
SIRT1	SIRT7	ENSMODP00000021523	ENSMODP00000003748	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 7.	0.973
SIRT1	SMARCAD1	ENSMODP00000021523	ENSMODP00000054417	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.625
SIRT7	HDAC1	ENSMODP00000003748	ENSMODP00000021783	Sirtuin 7.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.436
SIRT7	HDAC2	ENSMODP00000003748	ENSMODP00000022264	Sirtuin 7.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.436
SIRT7	SIRT1	ENSMODP00000003748	ENSMODP00000021523	Sirtuin 7.	Deacetylase sirtuin-type domain-containing protein.	0.973
SMARCAD1	SIRT1	ENSMODP00000054417	ENSMODP00000021523	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.625