STRINGSTRING
AQR AQR F7FA46_MONDO F7FA46_MONDO SNW1 SNW1 RBM22 RBM22 SYF2 SYF2 PRPF8 PRPF8 LOC100028830 LOC100028830 EFTUD2 EFTUD2 SNRPA1 SNRPA1 PPIL1 PPIL1 XAB2 XAB2 DHX8 DHX8 F7FRP8_MONDO F7FRP8_MONDO CWC15 CWC15 SNRPD3 SNRPD3 ENSMODP00000051992 ENSMODP00000051992 PLRG1 PLRG1 SNRPB SNRPB SNRPD2 SNRPD2 SNRPF SNRPF BCAS2 BCAS2 SNRNP40 SNRNP40 PPIE PPIE CDC40 CDC40 PRPF19 PRPF19 SNRPD1 SNRPD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1457 aa)
F7FA46_MONDOUncharacterized protein. (227 aa)
SNW1SNW domain containing 1. (536 aa)
RBM22Uncharacterized protein. (420 aa)
SYF2Uncharacterized protein. (258 aa)
PRPF8Pre-mRNA processing factor 8. (2317 aa)
LOC100028830Uncharacterized protein. (685 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (170 aa)
XAB2XPA binding protein 2. (862 aa)
DHX8DEAH-box helicase 8. (1196 aa)
F7FRP8_MONDOUncharacterized protein. (422 aa)
CWC15Uncharacterized protein. (231 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
ENSMODP00000051992Uncharacterized protein. (681 aa)
PLRG1Pleiotropic regulator 1. (621 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (273 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (108 aa)
SNRPFSmall nuclear ribonucleoprotein polypeptide F. (86 aa)
BCAS2BCAS2 pre-mRNA processing factor. (225 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (361 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
CDC40Cell division cycle 40. (579 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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