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DDX47 | DEAD-box helicase 47; Belongs to the DEAD box helicase family. (459 aa) | ||||
DDIT4 | DNA damage inducible transcript 4. (226 aa) | ||||
CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa) | ||||
HIPK1 | Homeodomain interacting protein kinase 1. (1211 aa) | ||||
VDAC2 | Voltage dependent anion channel 2. (283 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (969 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1584 aa) | ||||
COL2A1 | Collagen type II alpha 1 chain. (886 aa) | ||||
BCL2L10 | Uncharacterized protein. (189 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa) | ||||
SORT1 | Sortilin. (693 aa) | ||||
TM2D1 | TM2 domain containing 1. (208 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1492 aa) | ||||
INHBA | Inhibin subunit beta A. (426 aa) | ||||
E2F1 | E2F transcription factor 1. (443 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (902 aa) | ||||
EPHA2 | EPH receptor A2. (886 aa) | ||||
ZNF622 | Zinc finger protein 622. (467 aa) | ||||
DDX5 | Uncharacterized protein; Belongs to the DEAD box helicase family. (614 aa) | ||||
TFPT | TCF3 fusion partner. (246 aa) | ||||
FAIM2 | Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa) | ||||
CASP3 | Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa) | ||||
FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (238 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (188 aa) | ||||
SNW1 | SNW domain containing 1. (536 aa) | ||||
CASP6 | Uncharacterized protein; Belongs to the peptidase C14A family. (279 aa) | ||||
NOL3 | CARD domain-containing protein. (279 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (361 aa) | ||||
BCL2L11 | BCL2 like 11. (205 aa) | ||||
TNFSF12 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (291 aa) | ||||
PARP2 | Poly [ADP-ribose] polymerase. (745 aa) | ||||
NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) | ||||
IVNS1ABP | Influenza virus NS1A binding protein. (717 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (461 aa) | ||||
NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa) | ||||
WWOX | Uncharacterized protein. (188 aa) | ||||
STK24 | Serine/threonine kinase 24. (430 aa) | ||||
CHEK2 | Checkpoint kinase 2. (531 aa) | ||||
CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (545 aa) | ||||
USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1374 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (706 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa) | ||||
SGPL1 | Sphingosine-1-phosphate lyase 1. (604 aa) | ||||
PDX1 | Homeobox domain-containing protein. (290 aa) | ||||
PDK1 | Protein-serine/threonine kinase. (427 aa) | ||||
BMI1 | RING-type domain-containing protein. (312 aa) | ||||
LOC103100524 | Uncharacterized protein. (408 aa) | ||||
ATF4 | Activating transcription factor 4. (346 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1594 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) | ||||
ZNF385B | Zinc finger protein 385B. (396 aa) | ||||
DELE1 | DAP3 binding cell death enhancer 1. (510 aa) | ||||
ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1058 aa) | ||||
IFI6 | Interferon alpha inducible protein 6. (129 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1430 aa) | ||||
P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa) | ||||
PDK2 | Protein-serine/threonine kinase. (407 aa) | ||||
DIABLO | Uncharacterized protein. (247 aa) | ||||
PCGF2 | Polycomb group ring finger 2. (348 aa) | ||||
DEDD2 | DED domain-containing protein. (409 aa) | ||||
E2F2 | E2F transcription factor 2. (377 aa) | ||||
MLH1 | MutL homolog 1. (731 aa) | ||||
CX3CL1 | SCY domain-containing protein. (409 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
TIMM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (369 aa) | ||||
SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (178 aa) | ||||
PPARD | Peroxisome proliferator activated receptor delta. (441 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (204 aa) | ||||
DAXX | Death domain associated protein. (739 aa) | ||||
USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1134 aa) | ||||
CRIP1 | LIM zinc-binding domain-containing protein. (77 aa) | ||||
PIDD1 | Uncharacterized protein. (272 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) | ||||
CFLAR | Uncharacterized protein. (266 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (472 aa) | ||||
F6TMI5_MONDO | Uncharacterized protein. (174 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1130 aa) | ||||
NUPR1 | Uncharacterized protein. (82 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
BOK | BCL2 family apoptosis regulator BOK. (213 aa) | ||||
PTGIS | Prostaglandin I2 synthase. (518 aa) | ||||
CEBPB | CCAAT enhancer binding protein beta. (364 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (455 aa) | ||||
RHOT2 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (622 aa) | ||||
DIDO1 | Death inducer-obliterator 1. (2452 aa) | ||||
SIRT1 | Deacetylase sirtuin-type domain-containing protein. (713 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1390 aa) | ||||
PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (447 aa) | ||||
ELL3 | Elongation factor for RNA polymerase II 3. (385 aa) | ||||
PDIA3 | Protein disulfide-isomerase. (506 aa) | ||||
PDE3A | Phosphodiesterase. (1169 aa) | ||||
TNFRSF1A | Uncharacterized protein. (453 aa) | ||||
F7G4F6_MONDO | TNFR-Cys domain-containing protein. (157 aa) | ||||
CASP8AP2 | Caspase 8 associated protein 2. (1940 aa) | ||||
F7CU55_MONDO | Uncharacterized protein. (261 aa) | ||||
WHAMM | WASP homolog associated with actin, golgi membranes and microtubules. (803 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1875 aa) | ||||
BCL2A1 | BCL2 related protein A1. (172 aa) | ||||
BCL2L1 | BCL2 like 1. (227 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (195 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (731 aa) | ||||
JMY | Junction mediating and regulatory protein, p53 cofactor. (963 aa) | ||||
TMEM109 | Transmembrane protein 109. (260 aa) | ||||
CD5 | Uncharacterized protein. (399 aa) | ||||
QRICH1 | Glutamine rich 1. (776 aa) | ||||
BNIP3L | BCL2 interacting protein 3 like. (220 aa) | ||||
HIC1 | HIC ZBTB transcriptional repressor 1. (746 aa) | ||||
RHOT1 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (707 aa) | ||||
MLLT11 | MLLT11 transcription factor 7 cofactor. (91 aa) | ||||
F6YW13_MONDO | DNA_MISMATCH_REPAIR_2 domain-containing protein. (641 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
ANXA6 | Annexin. (672 aa) | ||||
BAG6 | BCL2 associated athanogene 6. (1148 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (438 aa) | ||||
SFN | Stratifin; Belongs to the 14-3-3 family. (256 aa) | ||||
RNF186 | Ring finger protein 186. (226 aa) | ||||
NANOS3 | Nanos-type domain-containing protein; Belongs to the nanos family. (262 aa) | ||||
F6Y0U5_MONDO | DUF727 domain-containing protein. (138 aa) | ||||
BRCA2 | Tower domain-containing protein. (3324 aa) | ||||
F7G5T5_MONDO | Uncharacterized protein; Belongs to the peptidase C14A family. (284 aa) | ||||
LOC100032592 | Uncharacterized protein; Belongs to the peptidase C14A family. (375 aa) | ||||
FHIT | Uncharacterized protein. (78 aa) | ||||
PDCD10 | Uncharacterized protein. (149 aa) | ||||
F7BR70_MONDO | c-SKI_SMAD_bind domain-containing protein. (403 aa) | ||||
ERN2 | Endoplasmic reticulum to nucleus signaling 2. (880 aa) | ||||
G0S2 | G0/G1 switch 2. (102 aa) | ||||
ITPRIP | Inositol 1,4,5-trisphosphate receptor interacting protein. (616 aa) | ||||
PHLDA3 | Pleckstrin homology like domain family A member 3. (126 aa) | ||||
LOC100016987 | Uncharacterized protein; Belongs to the peptidase C14A family. (472 aa) | ||||
ITPRIPL2 | ITPRIP like 2. (534 aa) | ||||
MELK | Non-specific serine/threonine protein kinase. (608 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
PML | Uncharacterized protein. (1118 aa) | ||||
EP300 | E1A binding protein p300. (2454 aa) | ||||
F6QBX0_MONDO | Uncharacterized protein. (98 aa) | ||||
F6XW95_MONDO | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (567 aa) | ||||
K7E0Z8_MONDO | Protein-serine/threonine kinase. (267 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa) | ||||
CASP18 | Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa) | ||||
K7E453_MONDO | Uncharacterized protein; Belongs to the peptidase C14A family. (413 aa) | ||||
BBC3 | Uncharacterized protein. (318 aa) | ||||
ENSMODP00000041408 | Uncharacterized protein. (134 aa) | ||||
PAWR | Uncharacterized protein. (507 aa) | ||||
DAP | Uncharacterized protein. (185 aa) | ||||
STK3 | Serine/threonine kinase 3. (555 aa) | ||||
CTTN | Cortactin. (517 aa) | ||||
ENSMODP00000042674 | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (684 aa) | ||||
RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (399 aa) | ||||
ENSMODP00000042990 | Uncharacterized protein; Belongs to the DEAD box helicase family. (391 aa) | ||||
DAPL1 | Death associated protein like 1. (106 aa) | ||||
TMEM117 | Uncharacterized protein. (514 aa) | ||||
EDA2R | Ectodysplasin A2 receptor. (295 aa) | ||||
ENSMODP00000043309 | CARD domain-containing protein. (102 aa) | ||||
ENSMODP00000043433 | Uncharacterized protein. (94 aa) | ||||
ENSMODP00000043518 | CARD domain-containing protein. (110 aa) | ||||
UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1423 aa) | ||||
TRIB3 | Protein kinase domain-containing protein. (146 aa) | ||||
BAD | Uncharacterized protein. (212 aa) | ||||
MCL1 | MCL1 apoptosis regulator, BCL2 family member. (396 aa) | ||||
ENSMODP00000045422 | Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (763 aa) | ||||
ENSMODP00000045775 | SAM domain-containing protein. (300 aa) | ||||
HTRA2 | HtrA serine peptidase 2. (432 aa) | ||||
ENSMODP00000046545 | Uncharacterized protein; Belongs to the peptidase C14A family. (266 aa) | ||||
LOC654275 | Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa) | ||||
LOC100032604 | Uncharacterized protein; Belongs to the peptidase C14A family. (428 aa) | ||||
EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (588 aa) | ||||
AEN | Exonuclease domain-containing protein. (334 aa) | ||||
BAX | Uncharacterized protein. (296 aa) | ||||
STK4 | Serine/threonine kinase 4. (496 aa) | ||||
SELENOK | Uncharacterized protein. (194 aa) | ||||
TP53BP2 | Tumor protein p53 binding protein 2. (1166 aa) | ||||
ENSMODP00000049522 | Uncharacterized protein; Belongs to the DEAD box helicase family. (412 aa) | ||||
IL7 | Uncharacterized protein. (205 aa) | ||||
PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1167 aa) | ||||
MYBBP1A | Uncharacterized protein. (336 aa) | ||||
COA8 | Uncharacterized protein. (211 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (729 aa) | ||||
KRT18 | Keratin 18; Belongs to the intermediate filament family. (390 aa) | ||||
EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (628 aa) | ||||
ENSMODP00000051602 | CARD domain-containing protein. (94 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa) | ||||
CDIP1 | Cell death inducing p53 target 1. (249 aa) | ||||
DAB2IP | DAB2 interacting protein. (1180 aa) | ||||
ENSMODP00000054112 | CARD domain-containing protein. (104 aa) | ||||
HIP1 | Huntingtin interacting protein 1. (1030 aa) | ||||
ENSMODP00000054347 | Uncharacterized protein. (82 aa) | ||||
ENSMODP00000054407 | Uncharacterized protein. (157 aa) | ||||
DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (778 aa) | ||||
AIFM1 | Apoptosis inducing factor mitochondria associated 1. (589 aa) | ||||
ENSMODP00000054835 | Uncharacterized protein. (83 aa) | ||||
BAG3 | BCL2 associated athanogene 3. (586 aa) | ||||
BDKRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa) | ||||
RNF41 | RING-type domain-containing protein. (201 aa) | ||||
ARL6IP5 | PRA1 family protein. (123 aa) | ||||
GSKIP | DUF727 domain-containing protein. (138 aa) | ||||
CRADD | Death domain-containing protein. (210 aa) | ||||
FNIP2 | Folliculin interacting protein 2. (1170 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4010 aa) | ||||
NF1 | Neurofibromin 1. (2781 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa) | ||||
ENSMODP00000058493 | U1-type domain-containing protein. (131 aa) | ||||
UBE4B | Ubiquitination factor E4B. (1242 aa) | ||||
ENSMODP00000059541 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (693 aa) | ||||
FADD | Uncharacterized protein. (193 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa) | ||||
DAPK1 | Death associated protein kinase 1. (1428 aa) | ||||
INHBB | Inhibin subunit beta B. (374 aa) | ||||
ATM | TAN domain-containing protein. (112 aa) | ||||
APAF1 | Apoptotic peptidase activating factor 1. (1279 aa) |