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| | IVNS1ABP | Influenza virus NS1A binding protein. (717 aa) |
| | APAF1 | Apoptotic peptidase activating factor 1. (1279 aa) |
| | ATM | TAN domain-containing protein. (112 aa) |
| | ENSMODP00000058493 | U1-type domain-containing protein. (131 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4010 aa) |
| | FNIP2 | Folliculin interacting protein 2. (1170 aa) |
| | GSKIP | DUF727 domain-containing protein. (138 aa) |
| | ARL6IP5 | PRA1 family protein. (123 aa) |
| | BDKRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (589 aa) |
| | ENSMODP00000054407 | Uncharacterized protein. (157 aa) |
| | ENSMODP00000054347 | Uncharacterized protein. (82 aa) |
| | DAB2IP | DAB2 interacting protein. (1180 aa) |
| | CDIP1 | Cell death inducing p53 target 1. (249 aa) |
| | COA8 | Uncharacterized protein. (211 aa) |
| | MYBBP1A | Uncharacterized protein. (336 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1167 aa) |
| | ENSMODP00000049522 | Uncharacterized protein; Belongs to the DEAD box helicase family. (412 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1166 aa) |
| | SELENOK | Uncharacterized protein. (194 aa) |
| | BAX | Uncharacterized protein. (296 aa) |
| | AEN | Exonuclease domain-containing protein. (334 aa) |
| | ENSMODP00000046545 | Uncharacterized protein; Belongs to the peptidase C14A family. (266 aa) |
| | HTRA2 | HtrA serine peptidase 2. (432 aa) |
| | ENSMODP00000045775 | SAM domain-containing protein. (300 aa) |
| | ENSMODP00000045422 | Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (763 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (396 aa) |
| | BAD | Uncharacterized protein. (212 aa) |
| | TRIB3 | Protein kinase domain-containing protein. (146 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (295 aa) |
| | TMEM117 | Uncharacterized protein. (514 aa) |
| | ENSMODP00000042990 | Uncharacterized protein; Belongs to the DEAD box helicase family. (391 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (399 aa) |
| | ENSMODP00000042674 | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (684 aa) |
| | ENSMODP00000041408 | Uncharacterized protein. (134 aa) |
| | BBC3 | Uncharacterized protein. (318 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa) |
| | K7E0Z8_MONDO | Protein-serine/threonine kinase. (267 aa) |
| | EP300 | E1A binding protein p300. (2454 aa) |
| | PML | Uncharacterized protein. (1118 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (608 aa) |
| | PHLDA3 | Pleckstrin homology like domain family A member 3. (126 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (880 aa) |
| | F7BR70_MONDO | c-SKI_SMAD_bind domain-containing protein. (403 aa) |
| | PDCD10 | Uncharacterized protein. (149 aa) |
| | FHIT | Uncharacterized protein. (78 aa) |
| | BRCA2 | Tower domain-containing protein. (3324 aa) |
| | F6Y0U5_MONDO | DUF727 domain-containing protein. (138 aa) |
| | RNF186 | Ring finger protein 186. (226 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (256 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (438 aa) |
| | BAG6 | BCL2 associated athanogene 6. (1148 aa) |
| | F6YW13_MONDO | DNA_MISMATCH_REPAIR_2 domain-containing protein. (641 aa) |
| | MLLT11 | MLLT11 transcription factor 7 cofactor. (91 aa) |
| | HIC1 | HIC ZBTB transcriptional repressor 1. (746 aa) |
| | QRICH1 | Glutamine rich 1. (776 aa) |
| | TMEM109 | Transmembrane protein 109. (260 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (963 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (731 aa) |
| | BNIP3 | BCL2 interacting protein 3. (195 aa) |
| | BCL2L1 | BCL2 like 1. (227 aa) |
| | BCL2A1 | BCL2 related protein A1. (172 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1875 aa) |
| | WHAMM | WASP homolog associated with actin, golgi membranes and microtubules. (803 aa) |
| | TNFRSF1A | Uncharacterized protein. (453 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (385 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (447 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1390 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (713 aa) |
| | CEBPB | CCAAT enhancer binding protein beta. (364 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (213 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa) |
| | NUPR1 | Uncharacterized protein. (82 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | CRIP1 | LIM zinc-binding domain-containing protein. (77 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1134 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (204 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | MLH1 | MutL homolog 1. (731 aa) |
| | E2F2 | E2F transcription factor 2. (377 aa) |
| | DIABLO | Uncharacterized protein. (247 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | IFI6 | Interferon alpha inducible protein 6. (129 aa) |
| | ZNF385B | Zinc finger protein 385B. (396 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ATF4 | Activating transcription factor 4. (346 aa) |
| | PDK1 | Protein-serine/threonine kinase. (427 aa) |
| | PDX1 | Homeobox domain-containing protein. (290 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1374 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (545 aa) |
| | CHEK2 | Checkpoint kinase 2. (531 aa) |
| | STK24 | Serine/threonine kinase 24. (430 aa) |
| | WWOX | Uncharacterized protein. (188 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa) |
| | NOL3 | CARD domain-containing protein. (279 aa) |
| | BCL2L11 | BCL2 like 11. (205 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (461 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (226 aa) |
| | CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1211 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (969 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1584 aa) |
| | BCL2L10 | Uncharacterized protein. (189 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1492 aa) |
| | E2F1 | E2F transcription factor 1. (443 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (902 aa) |
| | EPHA2 | EPH receptor A2. (886 aa) |
| | ZNF622 | Zinc finger protein 622. (467 aa) |
| | DDX5 | Uncharacterized protein; Belongs to the DEAD box helicase family. (614 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | BCL2 | BCL2 apoptosis regulator. (188 aa) |
| | SNW1 | SNW domain containing 1. (536 aa) |
| | CASP6 | Uncharacterized protein; Belongs to the peptidase C14A family. (279 aa) |
