STRINGSTRING
PLCG1 PLCG1 ADCY8 ADCY8 GRM5 GRM5 NTNG1 NTNG1 ITPR1 ITPR1 TNR TNR DVL1 DVL1 CDH11 CDH11 IQSEC2 IQSEC2 PLAT PLAT DTNBP1 DTNBP1 DCC DCC INA INA CTNNB1 CTNNB1 NTNG2 NTNG2 LRFN2 LRFN2 GRASP GRASP LRRC4 LRRC4 GABBR1 GABBR1 PRKCI PRKCI CACNG3 CACNG3 GRM1 GRM1 P2RX3 P2RX3 LOC100617582 LOC100617582 NEFL NEFL F6XKU2_MONDO F6XKU2_MONDO CACNG2 CACNG2 F6TU13_MONDO F6TU13_MONDO K7E1M2_MONDO K7E1M2_MONDO ITGB1 ITGB1 PRKCZ PRKCZ BAIAP2 BAIAP2 CACNG4 CACNG4 NPTN NPTN ADCY1 ADCY1 STX3 STX3 PTPRA PTPRA ABR ABR CASK CASK APBA2 APBA2 PTPRD PTPRD AKAP12 AKAP12 DGKI DGKI ENSMODP00000053958 ENSMODP00000053958 GSG1L GSG1L ENSMODP00000056147 ENSMODP00000056147 LRRTM2 LRRTM2 APBA1 APBA1 CTNND1 CTNND1 CDK5 CDK5 EFNB2 EFNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
GRM5Glutamate metabotropic receptor 5. (890 aa)
NTNG1Netrin G1. (451 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
TNRTenascin R. (1358 aa)
DVL1Dishevelled segment polarity protein 1. (705 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (795 aa)
IQSEC2IQ motif and Sec7 domain 2. (1228 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
DTNBP1Dystrobrevin binding protein 1. (346 aa)
DCCDCC netrin 1 receptor. (1403 aa)
INAInternexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family. (538 aa)
CTNNB1Catenin beta 1. (781 aa)
NTNG2Netrin G2. (588 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (815 aa)
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (379 aa)
LRRC4Leucine rich repeat containing 4. (650 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (579 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (579 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (798 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
LOC100617582Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (550 aa)
F6XKU2_MONDOANF_receptor domain-containing protein. (250 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (302 aa)
F6TU13_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
K7E1M2_MONDOUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (357 aa)
NPTNNeuroplastin. (420 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (289 aa)
PTPRAProtein tyrosine phosphatase receptor type A. (876 aa)
ABRABR activator of RhoGEF and GTPase. (1235 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
APBA2Amyloid beta precursor protein binding family A member 2. (752 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
AKAP12Uncharacterized protein. (2839 aa)
DGKIDiacylglycerol kinase. (1117 aa)
ENSMODP00000053958Uncharacterized protein. (296 aa)
GSG1LUncharacterized protein. (390 aa)
ENSMODP00000056147ANF_receptor domain-containing protein. (332 aa)
LRRTM2Uncharacterized protein. (516 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (860 aa)
CTNND1Catenin delta 1. (965 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
EFNB2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (333 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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