38 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F7F7P9_MONDO	Uncharacterized protein. (359 aa)
	P4HB	Protein disulfide-isomerase. (510 aa)
	LRRC45	Leucine rich repeat containing 45. (674 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (922 aa)
	TESK1	Testis associated actin remodelling kinase 1. (816 aa)
	UNC13D	Unc-13 homolog D. (1064 aa)
	DMTN	Dematin actin binding protein. (406 aa)
	RREB1	Ras responsive element binding protein 1. (1736 aa)
	CRK	CRK proto-oncogene, adaptor protein. (297 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	CALR	Calreticulin. (418 aa)
	CSPG5	Chondroitin sulfate proteoglycan 5. (578 aa)
	F6T9J4_MONDO	Uncharacterized protein. (191 aa)
	ARPC2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (330 aa)
	CRKL	Uncharacterized protein. (303 aa)
	LIMS2	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
	HPSE	Heparanase. (544 aa)
	CIB1	Calcium and integrin binding 1. (194 aa)
	CASS4	Cas scaffold protein family member 4. (830 aa)
	CDC42	Cell division cycle 42. (191 aa)
	F7CI75_MONDO	Uncharacterized protein. (223 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (563 aa)
	C1QBP	Complement C1q binding protein. (315 aa)
	NEDD9	Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
	FLNA	Filamin A. (2558 aa)
	ENSMODP00000044543	PH domain-containing protein. (648 aa)
	ILK	Integrin linked kinase. (486 aa)
	FERMT2	Fermitin family member 2. (719 aa)
	CARMIL1	Capping protein regulator and myosin 1 linker 1. (1433 aa)
	LIMS1	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (387 aa)
	DAB2	DAB adaptor protein 2. (772 aa)
	ENSMODP00000055038	Thioredoxin domain-containing protein. (65 aa)
	ENSMODP00000056454	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (149 aa)
	ENSMODP00000057145	Thioredoxin domain-containing protein. (157 aa)
	ENSMODP00000057195	SH2 domain-containing protein. (119 aa)
	ENSMODP00000057283	Thioredoxin domain-containing protein. (163 aa)
	MYOC	Myocilin. (478 aa)
	S100A10	EF-hand domain-containing protein; Belongs to the S-100 family. (97 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARPC2	CDC42	ENSMODP00000019356	ENSMODP00000032375	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Cell division cycle 42.	0.449
ARPC2	F6T9J4_MONDO	ENSMODP00000019356	ENSMODP00000017781	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.449
ARPC2	F7CI75_MONDO	ENSMODP00000019356	ENSMODP00000032833	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.449
BRAF	ITGB3	ENSMODP00000034042	ENSMODP00000013615	B-Raf proto-oncogene, serine/threonine kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.500
CALR	ENSMODP00000055038	ENSMODP00000014423	ENSMODP00000055038	Calreticulin.	Thioredoxin domain-containing protein.	0.753
CALR	ENSMODP00000057145	ENSMODP00000014423	ENSMODP00000057145	Calreticulin.	Thioredoxin domain-containing protein.	0.753
CALR	ENSMODP00000057283	ENSMODP00000014423	ENSMODP00000057283	Calreticulin.	Thioredoxin domain-containing protein.	0.753
CALR	F7F7P9_MONDO	ENSMODP00000014423	ENSMODP00000001131	Calreticulin.	Uncharacterized protein.	0.901
CALR	P4HB	ENSMODP00000014423	ENSMODP00000003645	Calreticulin.	Protein disulfide-isomerase.	0.753
CASS4	CRK	ENSMODP00000029137	ENSMODP00000012751	Cas scaffold protein family member 4.	CRK proto-oncogene, adaptor protein.	0.639
CASS4	CRKL	ENSMODP00000029137	ENSMODP00000021994	Cas scaffold protein family member 4.	Uncharacterized protein.	0.639
CASS4	ENSMODP00000057195	ENSMODP00000029137	ENSMODP00000057195	Cas scaffold protein family member 4.	SH2 domain-containing protein.	0.639
CASS4	FERMT2	ENSMODP00000029137	ENSMODP00000048612	Cas scaffold protein family member 4.	Fermitin family member 2.	0.408
CDC42	ARPC2	ENSMODP00000032375	ENSMODP00000019356	Cell division cycle 42.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.449
CDC42	CRK	ENSMODP00000032375	ENSMODP00000012751	Cell division cycle 42.	CRK proto-oncogene, adaptor protein.	0.409
CDC42	ENSMODP00000056454	ENSMODP00000032375	ENSMODP00000056454	Cell division cycle 42.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.449
CDC42	F7CI75_MONDO	ENSMODP00000032375	ENSMODP00000032833	Cell division cycle 42.	Uncharacterized protein.	0.901
CDC42	FLNA	ENSMODP00000032375	ENSMODP00000044463	Cell division cycle 42.	Filamin A.	0.572
CRK	CASS4	ENSMODP00000012751	ENSMODP00000029137	CRK proto-oncogene, adaptor protein.	Cas scaffold protein family member 4.	0.639
CRK	CDC42	ENSMODP00000012751	ENSMODP00000032375	CRK proto-oncogene, adaptor protein.	Cell division cycle 42.	0.409