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| | HDAC8 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (379 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (336 aa) |
| | RNF111 | Ring finger protein 111. (997 aa) |
| | F6Z480_MONDO | UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa) |
| | F6ZU19_MONDO | Uncharacterized protein. (252 aa) |
| | GTPBP4 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa) |
| | FBXO2 | F-box protein 2. (265 aa) |
| | BAG5 | BCL2 associated athanogene 5. (505 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (977 aa) |
| | PRR7 | Proline rich 7, synaptic. (280 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | F6TDG8_MONDO | Uncharacterized protein. (89 aa) |
| | LOC100027495 | WD_REPEATS_REGION domain-containing protein. (458 aa) |
| | ISG15 | Uncharacterized protein. (155 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (768 aa) |
| | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4378 aa) |
| | FBXO4 | F-box protein 4. (387 aa) |
| | ARRDC3 | Arrestin domain containing 3. (414 aa) |
| | HSPA5 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (657 aa) |
| | RNF180 | Ring finger protein 180. (582 aa) |
| | FANCI | FA complementation group I. (1332 aa) |
| | CDC20B | Cell division cycle 20B. (519 aa) |
| | H9H7A8_MONDO | WD_REPEATS_REGION domain-containing protein. (467 aa) |
| | MAD2L1 | Mitotic arrest deficient 2 like 1. (205 aa) |
| | PIAS3 | Protein inhibitor of activated STAT 3. (629 aa) |
| | BAG2 | BCL2 associated athanogene 2. (288 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | WASHC1 | WASH complex subunit 1. (467 aa) |
| | DTX3L | RING-type domain-containing protein. (756 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (655 aa) |
| | PEF1 | Penta-EF-hand domain containing 1. (367 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (796 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (368 aa) |
| | SASH1 | Uncharacterized protein. (648 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (313 aa) |
| | HSPBP1 | HSPA (Hsp70) binding protein 1. (309 aa) |
| | KDM1A | Lysine demethylase 1A. (909 aa) |
| | GNL3L | CP-type G domain-containing protein. (567 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (498 aa) |
| | DAXX | Death domain associated protein. (739 aa) |
| | LIMK1 | LIM domain kinase 1. (602 aa) |
| | KLHL40 | Kelch like family member 40. (486 aa) |
| | COPS9 | Uncharacterized protein. (106 aa) |
| | HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa) |
| | TTC36 | Tetratricopeptide repeat domain 36. (190 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1012 aa) |
| | RASD2 | Uncharacterized protein. (266 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (347 aa) |
| | FBXO33 | F-box protein 33. (563 aa) |
| | SPRTN | SprT-like domain-containing protein. (251 aa) |
| | MYCBP2 | MYC binding protein 2. (4761 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (965 aa) |
| | N4BP1 | RNase_Zc3h12a domain-containing protein. (788 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (506 aa) |
| | HMG20A | High mobility group 20A. (347 aa) |
| | UBA2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa) |
| | GLMN | Glomulin, FKBP associated protein. (604 aa) |
| | F6SPV4_MONDO | Uncharacterized protein. (710 aa) |
| | GNL3 | G protein nucleolar 3. (544 aa) |
| | NHLRC1 | NHL repeat containing E3 ubiquitin protein ligase 1. (405 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (223 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | PARP10 | Poly [ADP-ribose] polymerase. (923 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (215 aa) |
| | UBE2V2 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (146 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (543 aa) |
| | TNIP1 | TNFAIP3 interacting protein 1. (589 aa) |
| | BMI1 | RING-type domain-containing protein. (312 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (330 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (830 aa) |
| | FBXO5 | F-box protein 5. (457 aa) |
| | AIMP2 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (322 aa) |
| | USP44 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (716 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (540 aa) |
| | IVNS1ABP | Influenza virus NS1A binding protein. (717 aa) |
| | BUB3 | WD_REPEATS_REGION domain-containing protein. (334 aa) |
| | AMER1 | Uncharacterized protein. (1024 aa) |
| | DCUN1D3 | DCN1-like protein. (308 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | F6PS88_MONDO | WD_REPEATS_REGION domain-containing protein. (469 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | TSPO | Uncharacterized protein. (275 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (614 aa) |
| | GPS2 | G protein pathway suppressor 2. (325 aa) |
| | PHF23 | PHD finger protein 23. (432 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2764 aa) |
| | F6ZDC9_MONDO | WD_REPEATS_REGION domain-containing protein. (484 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (761 aa) |
| | RWDD3 | RWD domain containing 3. (277 aa) |
| | PABPN1L | RRM domain-containing protein. (302 aa) |
| | DCUN1D2 | DCN1-like protein. (268 aa) |
| | F7FBJ1_MONDO | Uncharacterized protein. (286 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | SIRT7 | Sirtuin 7. (521 aa) |
| | WFS1 | Wolframin ER transmembrane glycoprotein. (878 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (901 aa) |
| | MTBP | MDM2 binding protein. (897 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa) |
| | RASSF5 | Ras association domain family member 5. (422 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (933 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (892 aa) |
| | EPAS1 | HIF-1a_CTAD domain-containing protein. (336 aa) |
| | DCUN1D5 | DCN1-like protein. (237 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (494 aa) |
| | PDCD6 | Programmed cell death 6. (193 aa) |
| | BIRC2 | Uncharacterized protein. (383 aa) |
| | LOC100010741 | CARD domain-containing protein. (585 aa) |
| | BUB1B | BUB1 N-terminal domain-containing protein. (1070 aa) |
| | OTUD4 | OTU deubiquitinase 4. (1146 aa) |
| | CHP1 | Calcineurin like EF-hand protein 1. (195 aa) |
| | INAVA | Innate immunity activator. (578 aa) |
| | ENSMODP00000059880 | DUSP domain-containing protein. (168 aa) |
| | NOP53 | NOP53 ribosome biogenesis factor. (497 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (242 aa) |
| | TOLLIP | CUE domain-containing protein. (274 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (578 aa) |
| | DCUN1D1 | DCN1-like protein. (321 aa) |
| | MASTL | Microtubule associated serine/threonine kinase like. (909 aa) |
| | BIRC7 | RING-type domain-containing protein. (420 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa) |
| | COMMD1 | Copper metabolism domain containing 1. (242 aa) |
| | ENSMODP00000058521 | Uncharacterized protein. (149 aa) |
| | UFL1 | UFM1 specific ligase 1. (794 aa) |
| | PLAA | Phospholipase A2 activating protein. (1045 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa) |
| | PARK7 | DJ-1_PfpI domain-containing protein. (189 aa) |
| | OTUB2 | OTU domain-containing protein. (261 aa) |
| | ENSMODP00000057410 | Uncharacterized protein. (181 aa) |
| | SH3RF2 | SH3 domain containing ring finger 2. (752 aa) |
| | TANK | TRAF family member associated NFKB activator. (473 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1055 aa) |
| | U2AF2 | Uncharacterized protein. (291 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (637 aa) |
| | MTA1 | Metastasis associated 1. (718 aa) |
| | WBP1L | WW domain binding protein 1 like. (392 aa) |
| | ENSMODP00000047672 | HECT domain-containing protein. (93 aa) |
| | ENSMODP00000046971 | Uncharacterized protein. (189 aa) |
| | WDR48 | WD repeat domain 48. (704 aa) |
| | SPHK1 | Sphingosine kinase 1. (454 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (345 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (252 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (683 aa) |
| | TRIB3 | Protein kinase domain-containing protein. (146 aa) |
| | CDC20 | Cell division cycle 20. (711 aa) |
| | ENSMODP00000043254 | Uncharacterized protein. (71 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | SAE1 | SUMO1 activating enzyme subunit 1. (347 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa) |
| | NMI | Uncharacterized protein. (300 aa) |
| | AXIN1 | Axin 1. (875 aa) |
| | K7E4E3_MONDO | WD_REPEATS_REGION domain-containing protein. (454 aa) |
| | SQSTM1 | Sequestosome 1. (444 aa) |
| | PARK2 | RBR-type E3 ubiquitin transferase. (74 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (878 aa) |
| | NDFIP2 | Nedd4 family interacting protein 2. (258 aa) |
| | PINK1 | Protein kinase domain-containing protein. (573 aa) |
| | WDR20 | WD repeat domain 20. (588 aa) |
| | BCL10 | CARD domain-containing protein. (245 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (541 aa) |
| | ENSMODP00000050889 | CARD domain-containing protein. (507 aa) |
| | ENSMODP00000050667 | Ubiquitin-like domain-containing protein. (89 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | ENSMODP00000050297 | RNase_Zc3h12a domain-containing protein. (388 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2026 aa) |
| | TBC1D7 | TBC1 domain family member 7. (300 aa) |
| | ENSMODP00000044993 | Uncharacterized protein. (58 aa) |
| | UBE2V1 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (219 aa) |
| | CAMLG | Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (305 aa) |
| | ENSMODP00000055864 | RING-type domain-containing protein. (319 aa) |
| | SVBP | Uncharacterized protein. (102 aa) |
| | ARRDC4 | Arrestin domain containing 4. (420 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (459 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (916 aa) |
| | UBXN1 | UBX domain protein 1. (224 aa) |
| | DCUN1D4 | DCN1-like protein. (376 aa) |
| | ENSMODP00000053960 | KH type-2 domain-containing protein. (115 aa) |
| | UBXN2A | SEP domain-containing protein. (387 aa) |
