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NCF4 NCF4 ENSMODP00000044597 ENSMODP00000044597 ENSMODP00000044314 ENSMODP00000044314 ETFA ETFA DLAT DLAT UQCRC1 UQCRC1 NDUFS5 NDUFS5 ENSMODP00000041899 ENSMODP00000041899 ENSMODP00000041618 ENSMODP00000041618 K7E0Z8_MONDO K7E0Z8_MONDO OGDHL OGDHL F7GAU3_MONDO F7GAU3_MONDO PDHX PDHX RRM1 RRM1 NOXA1 NOXA1 H9H824_MONDO H9H824_MONDO CYTB CYTB ND6 ND6 ND5 ND5 ND4 ND4 ND3 ND3 COX1 COX1 ND2 ND2 ND1 ND1 NDUFV1 NDUFV1 NDUFB5 NDUFB5 NDUFV3 NDUFV3 ETFB ETFB NDUFS3 NDUFS3 MRPS36 MRPS36 NDUFA8 NDUFA8 WDR93 WDR93 NDUFB11 NDUFB11 BCKDHB BCKDHB LOC100021123 LOC100021123 NDUFA9 NDUFA9 LDHB LDHB F7GFP7_MONDO F7GFP7_MONDO DUOX1 DUOX1 NDUFAB1 NDUFAB1 DLD DLD F7FY27_MONDO F7FY27_MONDO OGDH OGDH NDUFB10 NDUFB10 GLDC GLDC HSD17B8 HSD17B8 LOC100015788 LOC100015788 F6UE48_MONDO F6UE48_MONDO UQCRFS1 UQCRFS1 PDK2 PDK2 IDH3A IDH3A NDUFA2 NDUFA2 CYC1 CYC1 NDUFA1 NDUFA1 PDK1 PDK1 IDH3G IDH3G BCKDHA BCKDHA NDUFA10 NDUFA10 NDUFA13 NDUFA13 NCF2 NCF2 NDUFA6 NDUFA6 NCF1 NCF1 DLST DLST FOXRED1 FOXRED1 NDUFB6 NDUFB6 GPD2 GPD2 CYBA CYBA UQCR11 UQCR11 NDUFA3 NDUFA3 GMPR2 GMPR2 P4HB P4HB NOX4 NOX4 NDUFB7 NDUFB7 PDHB PDHB F6QXR2_MONDO F6QXR2_MONDO F6RHS1_MONDO F6RHS1_MONDO BCKDK BCKDK LOC100030784 LOC100030784 SDHA SDHA NDUFC1 NDUFC1 ENSMODP00000060103 ENSMODP00000060103 ENSMODP00000059993 ENSMODP00000059993 ENSMODP00000059300 ENSMODP00000059300 LOC100031988 LOC100031988 NOXO1 NOXO1 ENSMODP00000057883 ENSMODP00000057883 ENSMODP00000057416 ENSMODP00000057416 ENSMODP00000057283 ENSMODP00000057283 ENSMODP00000057145 ENSMODP00000057145 ENSMODP00000056768 ENSMODP00000056768 SDHD SDHD NDUFS7 NDUFS7 ENSMODP00000055590 ENSMODP00000055590 ENSMODP00000055038 ENSMODP00000055038 SDHB SDHB NDUFS8 NDUFS8 GMPR GMPR NDUFS4 NDUFS4 LOC100028075 LOC100028075 ENSMODP00000053667 ENSMODP00000053667 CBR4 CBR4 CAT CAT NDUFB9 NDUFB9 ENSMODP00000051781 ENSMODP00000051781 DBT DBT NDUFB8 NDUFB8 IDH3B IDH3B NDUFA7 NDUFA7 NDUFC2 NDUFC2 ENSMODP00000049451 ENSMODP00000049451 ENSMODP00000049308 ENSMODP00000049308 GPD1L GPD1L NDUFB4 NDUFB4 NDUFS1 NDUFS1 NDUFV2 NDUFV2 NDUFB1 NDUFB1 ENSMODP00000048018 ENSMODP00000048018 NDUFS2 NDUFS2 PDHA1 PDHA1 LOC100030139 LOC100030139 SDHC SDHC ENSMODP00000046455 ENSMODP00000046455 ENSMODP00000045796 ENSMODP00000045796 NDUFA5 NDUFA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCF4Neutrophil cytosolic factor 4. (340 aa)
ENSMODP00000044597Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (190 aa)
ENSMODP00000044314NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (110 aa)
ETFAElectron transfer flavoprotein subunit alpha. (334 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (511 aa)
NDUFS5Uncharacterized protein. (171 aa)
ENSMODP00000041899Uncharacterized protein. (85 aa)
ENSMODP00000041618Uncharacterized protein. (93 aa)
K7E0Z8_MONDOProtein-serine/threonine kinase. (267 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
F7GAU3_MONDOUncharacterized protein. (235 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (498 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (745 aa)
NOXA1Uncharacterized protein. (449 aa)
H9H824_MONDONADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (114 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (382 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (166 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (608 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (116 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
NDUFV1NADH:ubiquinone oxidoreductase core subunit V1. (438 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (195 aa)
NDUFV3Uncharacterized protein. (421 aa)
ETFBETF domain-containing protein. (210 aa)
NDUFS3Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (539 aa)
MRPS36Mitochondrial ribosomal protein S36. (102 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
WDR93Uncharacterized protein. (673 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (157 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (383 aa)
LOC100021123Glycerol-3-phosphate dehydrogenase [NAD(+)]. (325 aa)
NDUFA9Epimerase domain-containing protein. (377 aa)
LDHBL-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. (378 aa)
F7GFP7_MONDOUncharacterized protein. (451 aa)
DUOX1Dual oxidase 1. (1542 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
DLDDihydrolipoyl dehydrogenase. (468 aa)
F7FY27_MONDOEpimerase domain-containing protein. (377 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1033 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
LOC100015788Uncharacterized protein. (82 aa)
F6UE48_MONDOUncharacterized protein. (82 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (100 aa)
CYC1Cytochrome c1. (320 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (64 aa)
PDK1Protein-serine/threonine kinase. (427 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (439 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (363 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
NCF2Neutrophil cytosolic factor 2. (528 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NCF1Neutrophil cytosolic factor 1. (389 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
FOXRED1FAD dependent oxidoreductase domain containing 1. (486 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (127 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa)
CYBACytochrome b-245 alpha chain. (191 aa)
UQCR11Uncharacterized protein. (56 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (80 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (358 aa)
P4HBProtein disulfide-isomerase. (510 aa)
NOX4NADPH oxidase 4. (578 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (124 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (371 aa)
F6QXR2_MONDOUncharacterized protein. (68 aa)
F6RHS1_MONDOUCR_hinge domain-containing protein. (111 aa)
BCKDKProtein-serine/threonine kinase. (332 aa)
LOC100030784NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (137 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (77 aa)
ENSMODP00000060103Uncharacterized protein. (92 aa)
ENSMODP00000059993Uncharacterized protein. (70 aa)
ENSMODP00000059300zf-CHCC domain-containing protein. (115 aa)
LOC100031988NAD_binding_1 domain-containing protein. (175 aa)
NOXO1Uncharacterized protein. (334 aa)
ENSMODP00000057883Uncharacterized protein. (53 aa)
ENSMODP00000057416Uncharacterized protein. (58 aa)
ENSMODP00000057283Thioredoxin domain-containing protein. (163 aa)
ENSMODP00000057145Thioredoxin domain-containing protein. (157 aa)
ENSMODP00000056768Uncharacterized protein. (71 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (215 aa)
ENSMODP00000055590Uncharacterized protein. (94 aa)
ENSMODP00000055038Thioredoxin domain-containing protein. (65 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
NDUFS84Fe-4S ferredoxin-type domain-containing protein. (64 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (313 aa)
NDUFS4Uncharacterized protein. (180 aa)
LOC100028075Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (143 aa)
ENSMODP00000053667Uncharacterized protein. (84 aa)
CBR4Uncharacterized protein. (237 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (529 aa)
NDUFB9Uncharacterized protein; Belongs to the complex I LYR family. (249 aa)
ENSMODP00000051781Pyr_redox_2 domain-containing protein. (132 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (503 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
NDUFA7Uncharacterized protein. (186 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
ENSMODP00000049451E1_dh domain-containing protein. (101 aa)
ENSMODP00000049308Uncharacterized protein. (74 aa)
GPD1LNAD_Gly3P_dh_C domain-containing protein. (117 aa)
NDUFB4Uncharacterized protein. (127 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (726 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (279 aa)
NDUFB1Uncharacterized protein. (58 aa)
ENSMODP00000048018Uncharacterized protein. (99 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (480 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
LOC100030139Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
ENSMODP00000046455Uncharacterized protein. (82 aa)
ENSMODP00000045796NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (184 aa)
NDUFA5Uncharacterized protein. (133 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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