STRINGSTRING
ADRA2C ADRA2C IL10 IL10 FBXW7 FBXW7 MILL-like MILL-like ARC ARC PARK7 PARK7 ENSMODP00000056096 ENSMODP00000056096 RELN RELN PINK1 PINK1 EPGN EPGN HDAC6 HDAC6 RWDD1 RWDD1 CACNG4 CACNG4 SHANK3 SHANK3 NEURL1 NEURL1 ITGB1 ITGB1 CACNG2 CACNG2 GREM1 GREM1 IFNGR2 IFNGR2 AREG AREG EREG EREG HDAC2 HDAC2 HDAC1 HDAC1 JAK2 JAK2 ADAM17 ADAM17 HBEGF HBEGF TGFA TGFA EDN1 EDN1 ADRA2A ADRA2A HIF1A HIF1A NCF1 NCF1 ADRA2B ADRA2B FBXW9 FBXW9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADRA2CAdrenoceptor alpha 2C. (469 aa)
IL10Interleukin 10. (173 aa)
FBXW7F-box and WD repeat domain containing 7. (892 aa)
MILL-likeMHC class I-like located near the LRC-like; Belongs to the MHC class I family. (343 aa)
ARCActivity regulated cytoskeleton associated protein. (400 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
ENSMODP00000056096Ig-like domain-containing protein; Belongs to the MHC class I family. (376 aa)
RELNReelin. (3458 aa)
PINK1Protein kinase domain-containing protein. (573 aa)
EPGNEGF-like domain-containing protein. (152 aa)
HDAC6Histone deacetylase 6. (1106 aa)
RWDD1RWD domain-containing protein. (240 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (357 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1695 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (577 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (302 aa)
GREM1Gremlin. (184 aa)
IFNGR2Uncharacterized protein. (344 aa)
AREGAmphiregulin. (237 aa)
EREGEpiregulin. (179 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
ADAM17ADAM metallopeptidase domain 17. (747 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TGFATransforming growth factor alpha. (159 aa)
EDN1Endothelin 1. (214 aa)
ADRA2AAdrenoceptor alpha 2A. (438 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (830 aa)
NCF1Neutrophil cytosolic factor 1. (389 aa)
ADRA2BAdrenoceptor alpha 2B. (441 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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