(45 nodes) Z disc network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IGSF22	Immunoglobulin superfamily member 22. (1163 aa)
	CFL2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (195 aa)
	PDLIM1	PDZ and LIM domain 1. (327 aa)
	F6R6I4_MONDO	Uncharacterized protein. (214 aa)
	NEB	Nebulin. (6641 aa)
	C1H10orf71	DUF4585 domain-containing protein. (1448 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (672 aa)
	F6VV34_MONDO	Uncharacterized protein. (1243 aa)
	CAPN3	Calpain 3; Belongs to the peptidase C2 family. (777 aa)
	LDB3	LIM domain binding 3. (679 aa)
	LOC100016282	Uncharacterized protein. (538 aa)
	SLC4A1	Anion exchange protein. (1013 aa)
	MYOZ2	Uncharacterized protein. (304 aa)
	ENSMODP00000044479	Uncharacterized protein. (455 aa)
	FBXL22	F-box domain-containing protein. (232 aa)
	CHORDC1	CHORD domain-containing protein. (178 aa)
	ENSMODP00000048108	Uncharacterized protein. (144 aa)
	ENSMODP00000056667	Uncharacterized protein. (160 aa)
	MYPN	Myopalladin. (1309 aa)
	PDLIM3	Uncharacterized protein. (364 aa)
	LOC103094545	Uncharacterized protein. (384 aa)
	SPHKAP	SPHK1 interactor, AKAP domain containing. (1760 aa)
	GGPS1	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (299 aa)
	TCAP	Titin-cap. (171 aa)
	FLNC	Filamin C. (2653 aa)
	TRIM54	Tripartite motif containing 54. (360 aa)
	H9H6T5_MONDO	Uncharacterized protein. (561 aa)
	LOC100016634	Uncharacterized protein. (420 aa)
	SYNC	Syncoilin, intermediate filament protein; Belongs to the intermediate filament family. (508 aa)
	FHL3	Four and a half LIM domains 3. (280 aa)
	KY	Kyphoscoliosis peptidase. (656 aa)
	F7B2M8_MONDO	Uncharacterized protein. (348 aa)
	SYNPO2	Synaptopodin 2. (1241 aa)
	NEXN	Nexilin F-actin binding protein. (666 aa)
	TRIM13	Tripartite motif containing 13. (426 aa)
	SRI	Sorcin. (234 aa)
	MYOZ3	Myozenin 3. (249 aa)
	C6H7orf57	Chromosome 7 open reading frame 57. (369 aa)
	CAPN9	Calpain 9; Belongs to the peptidase C2 family. (752 aa)
	NEBL	Nebulette. (1013 aa)
	CSRP3	Cysteine and glycine rich protein 3. (232 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (897 aa)
	ACTN2	Actinin alpha 2. (894 aa)
	BMP10	Bone morphogenetic protein 10. (422 aa)
	ENSMODP00000016202	annotation not available (165 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	ACTN3	ENSMODP00000009304	ENSMODP00000010140	Actinin alpha 2.	Actinin alpha 3 (gene/pseudogene).	0.945
ACTN2	CSRP3	ENSMODP00000009304	ENSMODP00000011235	Actinin alpha 2.	Cysteine and glycine rich protein 3.	0.743
ACTN2	ENSMODP00000056667	ENSMODP00000009304	ENSMODP00000056667	Actinin alpha 2.	Uncharacterized protein.	0.621
ACTN2	F6VV34_MONDO	ENSMODP00000009304	ENSMODP00000000372	Actinin alpha 2.	Uncharacterized protein.	0.400
ACTN2	FLNC	ENSMODP00000009304	ENSMODP00000018821	Actinin alpha 2.	Filamin C.	0.418
ACTN2	IGSF22	ENSMODP00000009304	ENSMODP00000007886	Actinin alpha 2.	Immunoglobulin superfamily member 22.	0.400
ACTN2	LDB3	ENSMODP00000009304	ENSMODP00000056233	Actinin alpha 2.	LIM domain binding 3.	0.464
ACTN2	MYOZ2	ENSMODP00000009304	ENSMODP00000043437	Actinin alpha 2.	Uncharacterized protein.	0.812
ACTN2	MYOZ3	ENSMODP00000009304	ENSMODP00000011937	Actinin alpha 2.	Myozenin 3.	0.440
ACTN2	MYPN	ENSMODP00000009304	ENSMODP00000056803	Actinin alpha 2.	Myopalladin.	0.734
ACTN2	NEB	ENSMODP00000009304	ENSMODP00000004827	Actinin alpha 2.	Nebulin.	0.559
ACTN2	PDLIM1	ENSMODP00000009304	ENSMODP00000006532	Actinin alpha 2.	PDZ and LIM domain 1.	0.630
ACTN2	PDLIM3	ENSMODP00000009304	ENSMODP00000058524	Actinin alpha 2.	Uncharacterized protein.	0.684
ACTN2	TCAP	ENSMODP00000009304	ENSMODP00000016021	Actinin alpha 2.	Titin-cap.	0.501
ACTN3	ACTN2	ENSMODP00000010140	ENSMODP00000009304	Actinin alpha 3 (gene/pseudogene).	Actinin alpha 2.	0.945
ACTN3	CSRP3	ENSMODP00000010140	ENSMODP00000011235	Actinin alpha 3 (gene/pseudogene).	Cysteine and glycine rich protein 3.	0.520
ACTN3	ENSMODP00000056667	ENSMODP00000010140	ENSMODP00000056667	Actinin alpha 3 (gene/pseudogene).	Uncharacterized protein.	0.460
ACTN3	F6VV34_MONDO	ENSMODP00000010140	ENSMODP00000000372	Actinin alpha 3 (gene/pseudogene).	Uncharacterized protein.	0.400
ACTN3	IGSF22	ENSMODP00000010140	ENSMODP00000007886	Actinin alpha 3 (gene/pseudogene).	Immunoglobulin superfamily member 22.	0.400
ACTN3	MYOZ2	ENSMODP00000010140	ENSMODP00000043437	Actinin alpha 3 (gene/pseudogene).	Uncharacterized protein.	0.608