(23 nodes) Toll/interleukin-1 receptor homology (TIR) domain network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
	LOC100019659	TIR domain-containing protein. (954 aa)
	LOC103098388	TIR domain-containing protein. (430 aa)
	TLR10	Toll like receptor 10; Belongs to the Toll-like receptor family. (746 aa)
	TLR9	TIR domain-containing protein. (1063 aa)
	IL1R1	TIR domain-containing protein. (344 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (647 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
	IL1RAPL1	Interleukin 1 receptor accessory protein like 1. (437 aa)
	TICAM2	TIR domain-containing protein. (223 aa)
	SARM1	Sterile alpha and TIR motif containing 1. (718 aa)
	TICAM1	TRIF-NTD domain-containing protein. (713 aa)
	IL1RL2	Uncharacterized protein. (565 aa)
	IL1RL1	Uncharacterized protein. (546 aa)
	IL18R1	Uncharacterized protein. (533 aa)
	F7EHK1_MONDO	Uncharacterized protein. (565 aa)
	IL1RAPL2	Interleukin 1 receptor accessory protein like 2. (436 aa)
	PIK3AP1	Phosphoinositide-3-kinase adaptor protein 1. (806 aa)
	TIRAP	TIR domain-containing protein. (342 aa)
	TLR8	Toll like receptor 8; Belongs to the Toll-like receptor family. (1048 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	TLR6	Toll like receptor 6; Belongs to the Toll-like receptor family. (803 aa)
	TLR5	Toll like receptor 5; Belongs to the Toll-like receptor family. (861 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F7EHK1_MONDO	IL18R1	ENSMODP00000002923	ENSMODP00000002903	Uncharacterized protein.	Uncharacterized protein.	0.967
IL18R1	F7EHK1_MONDO	ENSMODP00000002903	ENSMODP00000002923	Uncharacterized protein.	Uncharacterized protein.	0.967
IL18R1	IL1RAP	ENSMODP00000002903	ENSMODP00000056082	Uncharacterized protein.	Interleukin 1 receptor accessory protein.	0.633
IL1R1	IL1RAP	ENSMODP00000054488	ENSMODP00000056082	TIR domain-containing protein.	Interleukin 1 receptor accessory protein.	0.805
IL1RAP	IL18R1	ENSMODP00000056082	ENSMODP00000002903	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.633
IL1RAP	IL1R1	ENSMODP00000056082	ENSMODP00000054488	Interleukin 1 receptor accessory protein.	TIR domain-containing protein.	0.805
IL1RAP	IL1RL1	ENSMODP00000056082	ENSMODP00000002882	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.972
IL1RAP	IL1RL2	ENSMODP00000056082	ENSMODP00000002864	Interleukin 1 receptor accessory protein.	Uncharacterized protein.	0.805
IL1RAPL2	TIRAP	ENSMODP00000003919	ENSMODP00000005670	Interleukin 1 receptor accessory protein like 2.	TIR domain-containing protein.	0.403
IL1RL1	IL1RAP	ENSMODP00000002882	ENSMODP00000056082	Uncharacterized protein.	Interleukin 1 receptor accessory protein.	0.972
IL1RL2	IL1RAP	ENSMODP00000002864	ENSMODP00000056082	Uncharacterized protein.	Interleukin 1 receptor accessory protein.	0.805
LOC100019659	SARM1	ENSMODP00000039895	ENSMODP00000024025	TIR domain-containing protein.	Sterile alpha and TIR motif containing 1.	0.466
LOC100019659	TICAM1	ENSMODP00000039895	ENSMODP00000001261	TIR domain-containing protein.	TRIF-NTD domain-containing protein.	0.467
LOC100019659	TICAM2	ENSMODP00000039895	ENSMODP00000017089	TIR domain-containing protein.	TIR domain-containing protein.	0.467
LOC100019659	TIRAP	ENSMODP00000039895	ENSMODP00000005670	TIR domain-containing protein.	TIR domain-containing protein.	0.482
LOC100019659	TLR9	ENSMODP00000039895	ENSMODP00000050794	TIR domain-containing protein.	TIR domain-containing protein.	0.575
LOC103098388	TLR4	ENSMODP00000040860	ENSMODP00000024473	TIR domain-containing protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.624
SARM1	LOC100019659	ENSMODP00000024025	ENSMODP00000039895	Sterile alpha and TIR motif containing 1.	TIR domain-containing protein.	0.466
SARM1	TICAM1	ENSMODP00000024025	ENSMODP00000001261	Sterile alpha and TIR motif containing 1.	TRIF-NTD domain-containing protein.	0.428
SARM1	TICAM2	ENSMODP00000024025	ENSMODP00000017089	Sterile alpha and TIR motif containing 1.	TIR domain-containing protein.	0.428