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| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1514 aa) |
| | METTL9 | Methyltransferase like 9. (323 aa) |
| | F6YT61_MONDO | PABS domain-containing protein. (238 aa) |
| | LOC103102723 | Uncharacterized protein. (258 aa) |
| | EEF1AKMT1 | EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. (244 aa) |
| | NDUFAF7 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (439 aa) |
| | F7EK41_MONDO | PABS domain-containing protein. (256 aa) |
| | TRMT5 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (506 aa) |
| | TGS1 | Trimethylguanosine synthase 1. (869 aa) |
| | METTL15 | Methyltransferase like 15. (406 aa) |
| | PCMTD1 | Uncharacterized protein. (357 aa) |
| | FTSJ3 | pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (839 aa) |
| | EEF1AKMT2 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (220 aa) |
| | TRMT2A | tRNA methyltransferase 2 homolog A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (663 aa) |
| | METTL16 | Uncharacterized protein. (207 aa) |
| | SRM | Spermidine synthase. (290 aa) |
| | TRMT1 | tRNA (guanine(26)-N(2))-dimethyltransferase. (638 aa) |
| | F7CBL9_MONDO | SAM_MT_TRM5_TYW2 domain-containing protein. (474 aa) |
| | HEMK1 | HemK methyltransferase family member 1. (359 aa) |
| | ETFBKMT | Uncharacterized protein. (266 aa) |
| | LOC100011572 | CheR domain-containing protein. (301 aa) |
| | CMTR1 | Cap methyltransferase 1. (835 aa) |
| | TRMT61A | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (417 aa) |
| | CIAPIN1 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (312 aa) |
| | PRMT1 | Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (390 aa) |
| | FBL | Uncharacterized protein. (324 aa) |
| | NSUN5 | NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (456 aa) |
| | BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor. (282 aa) |
| | WBSCR27 | Methyltransf_11 domain-containing protein. (254 aa) |
| | NNMT | Uncharacterized protein. (260 aa) |
| | CMTR2 | Cap methyltransferase 2. (764 aa) |
| | METTL6 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (295 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (691 aa) |
| | METTL21A | Methyltransferase like 21A. (217 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (293 aa) |
| | RRNAD1 | Ribosomal RNA adenine dimethylase domain containing 1. (481 aa) |
| | PCMT1 | Protein-L-isoaspartate (D-aspartate) O-methyltransferase. (371 aa) |
| | NSUN3 | NOP2/Sun RNA methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (337 aa) |
| | PCMTD2 | Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2. (362 aa) |
| | TRMT11 | tRNA methyltransferase 11 homolog. (460 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (354 aa) |
| | GNMT | Glycine N-methyltransferase. (295 aa) |
| | F7FNN5_MONDO | Methyltransf_11 domain-containing protein. (432 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (851 aa) |
| | COMT | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (260 aa) |
| | METTL25 | Methyltransferase like 25. (608 aa) |
| | GSTCD | Glutathione S-transferase C-terminal domain containing. (621 aa) |
| | N6AMT1 | N-6 adenine-specific DNA methyltransferase 1. (219 aa) |
| | METTL1 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (269 aa) |
| | EEF1AKMT3 | EEF1A lysine methyltransferase 3. (223 aa) |
| | TRMT12 | SAM_MT_TRM5_TYW2 domain-containing protein. (457 aa) |
| | RNMT | mRNA cap 0 methyltransferase domain-containing protein. (299 aa) |
| | FTSJ1 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (362 aa) |
| | PRMT6 | Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (378 aa) |
| | CARM1 | Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (561 aa) |
| | TPMT | Thiopurine S-methyltransferase. (245 aa) |
| | NSUN7 | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (724 aa) |
| | F7EVA4_MONDO | SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (768 aa) |
| | METTL18 | Methyltransferase like 18. (375 aa) |
| | F7GHX6_MONDO | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (469 aa) |
| | ASMT | Acetylserotonin O-methyltransferase. (334 aa) |
| | DIMT1 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (381 aa) |
| | TRMT2B | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (531 aa) |
| | TRMT61B | Uncharacterized protein. (506 aa) |
| | PRMT8 | Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (393 aa) |
| | ASMTL | Acetylserotonin O-methyltransferase like. (641 aa) |
| | ENSMODP00000042256 | Uncharacterized protein. (216 aa) |
| | ENSMODP00000042704 | Uncharacterized protein. (144 aa) |
| | METTL8 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (409 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (399 aa) |
| | LCMT2 | Leucine carboxyl methyltransferase 2. (623 aa) |
| | ENSMODP00000044920 | Uncharacterized protein. (209 aa) |
| | TFB2M | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (289 aa) |
| | ANTKMT | Adenine nucleotide translocase lysine methyltransferase. (219 aa) |
| | LOC100017350 | CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (472 aa) |
| | METTL22 | Methyltransferase like 22. (411 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | CSKMT | Citrate synthase lysine methyltransferase. (241 aa) |
| | PNMT | Phenylethanolamine N-methyltransferase. (281 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (733 aa) |
| | ECE2 | Uncharacterized protein. (884 aa) |
| | TRDMT1 | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (420 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (541 aa) |
| | MRM2 | FtsJ domain-containing protein. (244 aa) |
| | METTL5 | Methyltransferase like 5. (213 aa) |
| | MEPCE | Methylphosphate capping enzyme. (678 aa) |
| | TFB1M | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (344 aa) |
| | ENSMODP00000053416 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1450 aa) |
| | METTL2A | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (385 aa) |
| | LOC100025184 | Methyltransf_11 domain-containing protein. (333 aa) |
| | PRMT9 | Protein arginine methyltransferase 9; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (843 aa) |
| | COMTD1 | Catechol-O-methyltransferase domain containing 1. (262 aa) |
| | METTL23 | Methyltransferase like 23. (190 aa) |
| | METTL7B | Methyltransferase like 7B. (261 aa) |
| | CARNMT1 | Carnosine N-methyltransferase 1. (448 aa) |
| | NSUN4 | NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (394 aa) |
| | NSUN2 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (799 aa) |
| | COQ5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (324 aa) |
| | FASN | Fatty acid synthase. (2512 aa) |
| | METTL11B | Methyltransferase like 11B. (283 aa) |
| | EEF1AKNMT | EEF1A lysine and N-terminal methyltransferase. (697 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1732 aa) |
| | THUMPD3 | THUMP domain containing 3. (511 aa) |
| | NDUFAF5 | NADH:ubiquinone oxidoreductase complex assembly factor 5. (352 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | F6U1X3_MONDO | Uncharacterized protein. (231 aa) |
| | LOC100026625 | Uncharacterized protein. (333 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | METTL21C | Methyltransferase like 21C. (275 aa) |
| | NTMT1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1. (223 aa) |
| | METTL17 | Methyltransferase like 17. (461 aa) |
| | TRMT1L | tRNA methyltransferase 1 like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (865 aa) |
| | ATPSCKMT | ATP synthase c subunit lysine N-methyltransferase. (231 aa) |
| | THUMPD2 | THUMP domain containing 2. (632 aa) |
| | NSUN6 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (480 aa) |
| | BCDIN3D | Bin3-type SAM domain-containing protein. (276 aa) |
| | DNMT3L | PHD-type domain-containing protein. (449 aa) |
| | METTL26 | Uncharacterized protein. (202 aa) |
| | ALKBH8 | AlkB homolog 8, tRNA methyltransferase. (637 aa) |
| | VCPKMT | Uncharacterized protein. (285 aa) |
| | CAMKMT | Calmodulin-lysine N-methyltransferase. (315 aa) |
| | HNMT | Uncharacterized protein. (148 aa) |
| | HENMT1 | Uncharacterized protein. (473 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase. (298 aa) |
