18 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100618318	C-X-C motif chemokine. (110 aa)
	LOC100022317	C-C motif chemokine. (99 aa)
	LOC103093843	C-C motif chemokine. (105 aa)
	LOC103093665	C-C motif chemokine. (226 aa)
	LOC100020842	C-C motif chemokine. (156 aa)
	LOC103099606	C-C motif chemokine. (95 aa)
	CXCL9	C-X-C motif chemokine. (123 aa)
	LOC100017328	C-C motif chemokine. (95 aa)
	LOC100017283	C-C motif chemokine. (91 aa)
	CCL19	C-C motif chemokine. (96 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1085 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1474 aa)
	LOC100023783	C-X-C motif chemokine. (130 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	ENSMODP00000050260	C-C motif chemokine. (121 aa)
	LOC100021456	C-C motif chemokine. (204 aa)
	LOC100020928	C-C motif chemokine. (98 aa)
	CCL20	C-C motif chemokine. (102 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL19	CCL20	ENSMODP00000038285	ENSMODP00000039409	C-C motif chemokine.	C-C motif chemokine.	0.519
CCL19	CXCL9	ENSMODP00000038285	ENSMODP00000039014	C-C motif chemokine.	C-X-C motif chemokine.	0.634
CCL19	LOC100017283	ENSMODP00000038285	ENSMODP00000038527	C-C motif chemokine.	C-C motif chemokine.	0.543
CCL19	LOC100017328	ENSMODP00000038285	ENSMODP00000038528	C-C motif chemokine.	C-C motif chemokine.	0.486
CCL19	LOC100023783	ENSMODP00000038285	ENSMODP00000023952	C-C motif chemokine.	C-X-C motif chemokine.	0.585
CCL19	LOC100618318	ENSMODP00000038285	ENSMODP00000023943	C-C motif chemokine.	C-X-C motif chemokine.	0.528
CCL19	LOC103093665	ENSMODP00000038285	ENSMODP00000023905	C-C motif chemokine.	C-C motif chemokine.	0.444
CCL20	CCL19	ENSMODP00000039409	ENSMODP00000038285	C-C motif chemokine.	C-C motif chemokine.	0.519
CCL20	CXCL8	ENSMODP00000039409	ENSMODP00000023940	C-C motif chemokine.	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.698
CCL20	CXCL9	ENSMODP00000039409	ENSMODP00000039014	C-C motif chemokine.	C-X-C motif chemokine.	0.533
CCL20	ENSMODP00000050260	ENSMODP00000039409	ENSMODP00000050260	C-C motif chemokine.	C-C motif chemokine.	0.510
CCL20	LOC100017283	ENSMODP00000039409	ENSMODP00000038527	C-C motif chemokine.	C-C motif chemokine.	0.662
CCL20	LOC100017328	ENSMODP00000039409	ENSMODP00000038528	C-C motif chemokine.	C-C motif chemokine.	0.644
CCL20	LOC100021456	ENSMODP00000039409	ENSMODP00000047913	C-C motif chemokine.	C-C motif chemokine.	0.445
CCL20	LOC100023783	ENSMODP00000039409	ENSMODP00000023952	C-C motif chemokine.	C-X-C motif chemokine.	0.809
CCL20	LOC100618318	ENSMODP00000039409	ENSMODP00000023943	C-C motif chemokine.	C-X-C motif chemokine.	0.636
CCL20	LOC103093665	ENSMODP00000039409	ENSMODP00000023905	C-C motif chemokine.	C-C motif chemokine.	0.669
CXCL8	CCL20	ENSMODP00000023940	ENSMODP00000039409	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	C-C motif chemokine.	0.698
CXCL8	CXCL9	ENSMODP00000023940	ENSMODP00000039014	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine.	0.739
CXCL8	ENSMODP00000050260	ENSMODP00000023940	ENSMODP00000050260	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	C-C motif chemokine.	0.531