55 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
	TNFSF15	TNF_2 domain-containing protein. (307 aa)
	IFN2	Type I interferon 2. (183 aa)
	LOC103101367	Uncharacterized protein. (211 aa)
	LOC100021368	Uncharacterized protein. (183 aa)
	IFN4	Type I interferon 4. (183 aa)
	TNFSF10	Tumor necrosis factor ligand superfamily member. (301 aa)
	ENSMODP00000053990	Interleukin-1. (153 aa)
	LOC103102395	Uncharacterized protein. (207 aa)
	ENSMODP00000050628	Interleukin-1. (99 aa)
	ENSMODP00000050260	C-C motif chemokine. (121 aa)
	NAMPT	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (522 aa)
	IFN7	Type I interferon 7. (183 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (251 aa)
	LOC100021456	C-C motif chemokine. (204 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
	LOC100020928	C-C motif chemokine. (98 aa)
	CCL20	C-C motif chemokine. (102 aa)
	CXCL9	C-X-C motif chemokine. (123 aa)
	LOC100017328	C-C motif chemokine. (95 aa)
	LOC100017283	C-C motif chemokine. (91 aa)
	TNFSF13	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (249 aa)
	CCL19	C-C motif chemokine. (96 aa)
	LOC100021258	Type I interferon 1. (198 aa)
	LOC100021467	Uncharacterized protein. (183 aa)
	GREM1	Gremlin. (184 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (448 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1474 aa)
	LOC100023783	C-X-C motif chemokine. (130 aa)
	LOC100618318	C-X-C motif chemokine. (110 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	LOC100022317	C-C motif chemokine. (99 aa)
	LOC103093843	C-C motif chemokine. (105 aa)
	LOC103093665	C-C motif chemokine. (226 aa)
	LOC100020842	C-C motif chemokine. (156 aa)
	LOC103099606	C-C motif chemokine. (95 aa)
	F7C7H2_MONDO	Interleukin; Belongs to the IL-15/IL-21 family. (158 aa)
	LTA	Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (231 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
	LTB	Lymphotoxin beta; Belongs to the tumor necrosis factor family. (251 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	IL5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (137 aa)
	IL1A	Interleukin-1. (263 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
	LOC100026042	Interleukin-1. (152 aa)
	IL36A	Interleukin-1. (157 aa)
	LOC100026087	Interleukin-1. (188 aa)
	IL36RN	Interleukin-1. (143 aa)
	IL1F10	Interleukin-1. (141 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (308 aa)
	LOC100025872	Left-right determination factor. (368 aa)
	IFNK	Type I interferon 9. (202 aa)
	LOC100021419	Type I interferon 5. (184 aa)
	IFN3	Uncharacterized protein. (184 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL19	CCL20	ENSMODP00000038285	ENSMODP00000039409	C-C motif chemokine.	C-C motif chemokine.	0.519
CCL19	CXCL9	ENSMODP00000038285	ENSMODP00000039014	C-C motif chemokine.	C-X-C motif chemokine.	0.634
CCL19	LOC100017283	ENSMODP00000038285	ENSMODP00000038527	C-C motif chemokine.	C-C motif chemokine.	0.543
CCL19	LOC100017328	ENSMODP00000038285	ENSMODP00000038528	C-C motif chemokine.	C-C motif chemokine.	0.486
CCL19	LOC100023783	ENSMODP00000038285	ENSMODP00000023952	C-C motif chemokine.	C-X-C motif chemokine.	0.585
CCL19	LOC100618318	ENSMODP00000038285	ENSMODP00000023943	C-C motif chemokine.	C-X-C motif chemokine.	0.528
CCL19	LOC103093665	ENSMODP00000038285	ENSMODP00000023905	C-C motif chemokine.	C-C motif chemokine.	0.444
CCL20	CCL19	ENSMODP00000039409	ENSMODP00000038285	C-C motif chemokine.	C-C motif chemokine.	0.519
CCL20	CXCL8	ENSMODP00000039409	ENSMODP00000023940	C-C motif chemokine.	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.698
CCL20	CXCL9	ENSMODP00000039409	ENSMODP00000039014	C-C motif chemokine.	C-X-C motif chemokine.	0.533
CCL20	ENSMODP00000050260	ENSMODP00000039409	ENSMODP00000050260	C-C motif chemokine.	C-C motif chemokine.	0.510
CCL20	IL1A	ENSMODP00000039409	ENSMODP00000017275	C-C motif chemokine.	Interleukin-1.	0.609
CCL20	IL1B	ENSMODP00000039409	ENSMODP00000017267	C-C motif chemokine.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.640
CCL20	LOC100017283	ENSMODP00000039409	ENSMODP00000038527	C-C motif chemokine.	C-C motif chemokine.	0.662
CCL20	LOC100017328	ENSMODP00000039409	ENSMODP00000038528	C-C motif chemokine.	C-C motif chemokine.	0.644
CCL20	LOC100021456	ENSMODP00000039409	ENSMODP00000047913	C-C motif chemokine.	C-C motif chemokine.	0.445
CCL20	LOC100023783	ENSMODP00000039409	ENSMODP00000023952	C-C motif chemokine.	C-X-C motif chemokine.	0.809
CCL20	LOC100618318	ENSMODP00000039409	ENSMODP00000023943	C-C motif chemokine.	C-X-C motif chemokine.	0.636
CCL20	LOC103093665	ENSMODP00000039409	ENSMODP00000023905	C-C motif chemokine.	C-C motif chemokine.	0.669
CCL20	TNF	ENSMODP00000039409	ENSMODP00000019686	C-C motif chemokine.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.517