STRINGSTRING
F6YCN3_MONDO F6YCN3_MONDO F6PHG0_MONDO F6PHG0_MONDO FNDC3B FNDC3B PIK3CA PIK3CA PIK3R1 PIK3R1 AREG AREG EREG EREG F7FV67_MONDO F7FV67_MONDO F7ASC3_MONDO F7ASC3_MONDO LOC100021198 LOC100021198 AAMP AAMP EPS15L1 EPS15L1 SH3GL2 SH3GL2 F6T9J4_MONDO F6T9J4_MONDO CBL CBL EGFR EGFR STAM STAM TGFA TGFA HBEGF HBEGF RPS27A RPS27A EPS15 EPS15 TGFB1I1 TGFB1I1 KRAS-2 KRAS-2 EGF EGF FNDC3A FNDC3A HRAS HRAS ENSMODP00000059044 ENSMODP00000059044 PTPRK PTPRK GAB1 GAB1 ENSMODP00000055874 ENSMODP00000055874 SH3KBP1 SH3KBP1 KRAS KRAS EPGN EPGN PTPRM PTPRM SPRY1 SPRY1 LRIG2 LRIG2 NRAS NRAS ENSMODP00000047773 ENSMODP00000047773 ENSMODP00000047294 ENSMODP00000047294 ENSMODP00000047027 ENSMODP00000047027 LOC100619355 LOC100619355 ENSMODP00000044759 ENSMODP00000044759 ENSMODP00000043793 ENSMODP00000043793 PTPN3 PTPN3 LPXN LPXN F7CI75_MONDO F7CI75_MONDO SPRY2 SPRY2 PTPRT PTPRT SH3GL1 SH3GL1 PLCG1 PLCG1 STAM2 STAM2 UBA52 UBA52 LRIG1 LRIG1 PTPN11 PTPN11 HGS HGS CSDE1 CSDE1 LRIG3 LRIG3 PAG1 PAG1 GRB2 GRB2 RNF222 RNF222 SOS1 SOS1 CDC42 CDC42 PXN PXN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6YCN3_MONDOUncharacterized protein. (406 aa)
F6PHG0_MONDOUncharacterized protein. (1190 aa)
FNDC3BFibronectin type III domain containing 3B. (1118 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
AREGAmphiregulin. (237 aa)
EREGEpiregulin. (179 aa)
F7FV67_MONDOUbiquitin-like domain-containing protein. (156 aa)
F7ASC3_MONDOUncharacterized protein. (274 aa)
LOC100021198Uncharacterized protein. (761 aa)
AAMPAngio associated migratory cell protein. (436 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (720 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
F6T9J4_MONDOUncharacterized protein. (191 aa)
CBLCbl proto-oncogene. (837 aa)
EGFRReceptor protein-tyrosine kinase. (1213 aa)
STAMSignal transducing adaptor molecule. (526 aa)
TGFATransforming growth factor alpha. (159 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
EPS15Uncharacterized protein. (683 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (442 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
EGFEpidermal growth factor. (1143 aa)
FNDC3AFibronectin type III domain containing 3A. (1204 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
ENSMODP00000059044SH2 domain-containing protein. (79 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1471 aa)
GAB1GRB2 associated binding protein 1. (743 aa)
ENSMODP00000055874EH domain-containing protein. (119 aa)
SH3KBP1Uncharacterized protein. (706 aa)
KRASGTPase KRas. (189 aa)
EPGNEGF-like domain-containing protein. (152 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1432 aa)
SPRY1Uncharacterized protein. (105 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1107 aa)
NRASGTPase NRas. (195 aa)
ENSMODP00000047773Uncharacterized protein. (373 aa)
ENSMODP00000047294Ubiquitin-like domain-containing protein. (92 aa)
ENSMODP00000047027VHS domain-containing protein. (70 aa)
LOC100619355Ubiquitin-like domain-containing protein. (77 aa)
ENSMODP00000044759Ubiquitin-like domain-containing protein. (75 aa)
ENSMODP00000043793Ubiquitin-like domain-containing protein. (104 aa)
PTPN3Protein tyrosine phosphatase non-receptor type 3. (1080 aa)
LPXNLeupaxin. (409 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
SPRY2Sprouty RTK signaling antagonist 2. (317 aa)
PTPRTUncharacterized protein. (1003 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
STAM2Signal transducing adaptor molecule 2. (526 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1095 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (779 aa)
CSDE1Cold shock domain containing E1. (845 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1121 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (428 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
RNF222Ring finger protein 222. (218 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
CDC42Cell division cycle 42. (191 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (590 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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