61 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNB5	G protein subunit beta 5. (353 aa)
	ADRA2C	Adrenoceptor alpha 2C. (469 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
	GCG	Glucagon. (181 aa)
	FAP	Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (759 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (571 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (788 aa)
	GNB2	G protein subunit beta 2. (367 aa)
	ADCY6	AC_N domain-containing protein. (313 aa)
	CACNA2D1-2	Uncharacterized protein. (105 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
	LOC100010184	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
	SNX19	Sorting nexin 19. (1015 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1076 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (912 aa)
	CACNB2	Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	ENSMODP00000046981	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	ENSMODP00000046905	THAP-type domain-containing protein. (214 aa)
	ENSMODP00000045559	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	MARCKS	Uncharacterized protein. (398 aa)
	THAP7	THAP domain containing 7. (314 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	GNA11	G protein subunit alpha 11. (359 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (471 aa)
	CACNA2D1	Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (960 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (872 aa)
	SLC2A2	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (518 aa)
	FFAR1	Free fatty acid receptor 1. (299 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (464 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor like 1. (664 aa)
	GNAQ	G protein subunit alpha q. (359 aa)
	GNA14	G protein subunit alpha 14. (355 aa)
	F6PM16_MONDO	Ca_chan_IQ domain-containing protein. (490 aa)
	KCNG2	Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (508 aa)
	ADRA2A	Adrenoceptor alpha 2A. (438 aa)
	THAP1	THAP domain containing 1. (213 aa)
	CACNB3	Calcium voltage-gated channel auxiliary subunit beta 3. (482 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1580 aa)
	KCNJ11	Potassium voltage-gated channel subfamily J member 11. (399 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	CACNA1E	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2388 aa)
	GNG10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (445 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	ENSMODP00000045559	ENSMODP00000008676	ENSMODP00000045559	ATP binding cassette subfamily C member 8.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.478
ABCC8	KCNJ11	ENSMODP00000008676	ENSMODP00000008683	ATP binding cassette subfamily C member 8.	Potassium voltage-gated channel subfamily J member 11.	0.998
ABCC8	PRKACA	ENSMODP00000008676	ENSMODP00000048595	ATP binding cassette subfamily C member 8.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.946
ABCC8	PRKACB	ENSMODP00000008676	ENSMODP00000000650	ATP binding cassette subfamily C member 8.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.483
ABCC8	RAPGEF4	ENSMODP00000008676	ENSMODP00000050440	ATP binding cassette subfamily C member 8.	Rap guanine nucleotide exchange factor 4.	0.985
ABCC8	SLC2A2	ENSMODP00000008676	ENSMODP00000020004	ATP binding cassette subfamily C member 8.	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.464
ADCY5	GNB5	ENSMODP00000055431	ENSMODP00000002374	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.496
ADCY5	GNG12	ENSMODP00000055431	ENSMODP00000000921	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.406
ADCY5	GNG13	ENSMODP00000055431	ENSMODP00000021082	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit gamma 13.	0.487
ADCY5	GNG4	ENSMODP00000055431	ENSMODP00000040227	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.505
ADCY5	GNG5	ENSMODP00000055431	ENSMODP00000051251	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.474
ADCY5	GNG7	ENSMODP00000055431	ENSMODP00000038443	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.420
ADCY5	GNGT2	ENSMODP00000055431	ENSMODP00000047365	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.472
ADCY6	GNB5	ENSMODP00000058527	ENSMODP00000002374	AC_N domain-containing protein.	G protein subunit beta 5.	0.496
ADCY6	GNG13	ENSMODP00000058527	ENSMODP00000021082	AC_N domain-containing protein.	G protein subunit gamma 13.	0.487
ADCY6	GNG4	ENSMODP00000058527	ENSMODP00000040227	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.492
ADCY6	GNG5	ENSMODP00000058527	ENSMODP00000051251	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.474
ADCY6	GNG7	ENSMODP00000058527	ENSMODP00000038443	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.420
ADCY6	GNGT2	ENSMODP00000058527	ENSMODP00000047365	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.472
ADRA2A	GNA11	ENSMODP00000012944	ENSMODP00000023891	Adrenoceptor alpha 2A.	G protein subunit alpha 11.	0.921