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FH FH DLST DLST SUCLG2 SUCLG2 ACO2 ACO2 SDHA SDHA FAHD1 FAHD1 DLD DLD SDHC SDHC IDH3B IDH3B ENSMODP00000051781 ENSMODP00000051781 SDHB SDHB SDHD SDHD ENSMODP00000059993 ENSMODP00000059993 IDH2 IDH2 NNT NNT SUCLG1 SUCLG1 OGDHL OGDHL OGDH OGDH MDH2 MDH2 IDH3A IDH3A SUCLA2 SUCLA2 ME2 ME2 IDH3G IDH3G
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FHFumarate hydratase. (504 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (541 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
FAHD1Fumarylacetoacetate hydrolase domain containing 1. (249 aa)
DLDDihydrolipoyl dehydrogenase. (468 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
ENSMODP00000051781Pyr_redox_2 domain-containing protein. (132 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
ENSMODP00000059993Uncharacterized protein. (70 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
NNTNicotinamide nucleotide transhydrogenase. (1086 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (371 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
MDH2Malate dehydrogenase. (338 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (464 aa)
ME2Malic enzyme. (584 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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