STRINGSTRING
PPARD PPARD SDHA SDHA F7FCH1_MONDO F7FCH1_MONDO FH FH LDHA LDHA LDHC LDHC DLST DLST SUCLG2 SUCLG2 PDHB PDHB SLC16A1 SLC16A1 PDP2 PDP2 ENSMODP00000059993 ENSMODP00000059993 MPC2 MPC2 PDK4 PDK4 L2HGDH L2HGDH SDHD SDHD SDHB SDHB PDPR PDPR ENSMODP00000051781 ENSMODP00000051781 BSG BSG IDH3B IDH3B HAGHL HAGHL ENSMODP00000049543 ENSMODP00000049543 ENSMODP00000049451 ENSMODP00000049451 ME3 ME3 ENSMODP00000047713 ENSMODP00000047713 PDHA1 PDHA1 SDHC SDHC LOC100028279 LOC100028279 PDP1 PDP1 SLC16A8 SLC16A8 DLAT DLAT ENSMODP00000042431 ENSMODP00000042431 FAHD1 FAHD1 GSTZ1 GSTZ1 SLC16A3 SLC16A3 K7E0Z8_MONDO K7E0Z8_MONDO F6RR47_MONDO F6RR47_MONDO OGDHL OGDHL PDHX PDHX F6YQ48_MONDO F6YQ48_MONDO MPC1 MPC1 F7BNV4_MONDO F7BNV4_MONDO SUCLG1 SUCLG1 NNT NNT MBLAC2 MBLAC2 ENSMODP00000024452 ENSMODP00000024452 IDH2 IDH2 ME1 ME1 LDHB LDHB F7GGA7_MONDO F7GGA7_MONDO ACO2 ACO2 DLD DLD OGDH OGDH HAGH HAGH PNKD PNKD VDAC1 VDAC1 MDH2 MDH2 GLO1 GLO1 F7EDE1_MONDO F7EDE1_MONDO PDK2 PDK2 IDH3A IDH3A SUCLA2 SUCLA2 ME2 ME2 F7EYJ1_MONDO F7EYJ1_MONDO PDK1 PDK1 D2HGDH D2HGDH IDH3G IDH3G ADHFE1 ADHFE1 PDK3 PDK3 LACTB2 LACTB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
F7FCH1_MONDOUncharacterized protein; Belongs to the LDH/MDH superfamily. (224 aa)
FHFumarate hydratase. (504 aa)
LDHAL-lactate dehydrogenase A chain. (332 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (318 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (541 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (371 aa)
SLC16A1Solute carrier family 16 member 1. (503 aa)
PDP2Pyruvate dehyrogenase phosphatase catalytic subunit 2. (608 aa)
ENSMODP00000059993Uncharacterized protein. (70 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (119 aa)
PDK4Protein-serine/threonine kinase. (423 aa)
L2HGDHDAO domain-containing protein. (445 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
PDPRPyruvate dehydrogenase phosphatase regulatory subunit. (886 aa)
ENSMODP00000051781Pyr_redox_2 domain-containing protein. (132 aa)
BSGUncharacterized protein. (391 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
HAGHLHydroxyacylglutathione hydrolase like. (282 aa)
ENSMODP00000049543Ldh_1_N domain-containing protein. (92 aa)
ENSMODP00000049451E1_dh domain-containing protein. (101 aa)
ME3Malic enzyme; Belongs to the malic enzymes family. (610 aa)
ENSMODP00000047713Ldh_1_N domain-containing protein. (99 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
LOC100028279L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (381 aa)
PDP1PPM-type phosphatase domain-containing protein. (696 aa)
SLC16A8Solute carrier family 16 member 8. (505 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
ENSMODP00000042431Ig-like domain-containing protein. (187 aa)
FAHD1Fumarylacetoacetate hydrolase domain containing 1. (249 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (260 aa)
SLC16A3Solute carrier family 16 member 3. (493 aa)
K7E0Z8_MONDOProtein-serine/threonine kinase. (267 aa)
F6RR47_MONDOL-lactate dehydrogenase. (228 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (498 aa)
F6YQ48_MONDOLactamase_B domain-containing protein. (253 aa)
MPC1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (171 aa)
F7BNV4_MONDOL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (279 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (371 aa)
NNTNicotinamide nucleotide transhydrogenase. (1086 aa)
MBLAC2Lactamase_B domain-containing protein. (279 aa)
ENSMODP00000024452L-lactate dehydrogenase A chain. (332 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
ME1Malic enzyme. (692 aa)
LDHBL-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. (378 aa)
F7GGA7_MONDOUncharacterized protein; Belongs to the LDH/MDH superfamily. (254 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
DLDDihydrolipoyl dehydrogenase. (468 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
HAGHLactamase_B domain-containing protein. (552 aa)
PNKDPNKD metallo-beta-lactamase domain containing. (369 aa)
VDAC1Voltage dependent anion channel 1. (400 aa)
MDH2Malate dehydrogenase. (338 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa)
F7EDE1_MONDOMalic enzyme. (569 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (464 aa)
ME2Malic enzyme. (584 aa)
F7EYJ1_MONDOProtein-serine/threonine kinase. (396 aa)
PDK1Protein-serine/threonine kinase. (427 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (543 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
ADHFE1Fe-ADH domain-containing protein. (467 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
LACTB2Lactamase beta 2. (288 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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