10 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HIPK2	Homeodomain interacting protein kinase 2. (1224 aa)
	DGCR8	DGCR8 microprocessor complex subunit. (774 aa)
	LBR	Tudor domain-containing protein. (612 aa)
	HTT	Huntingtin. (2899 aa)
	PVALB	Uncharacterized protein; Belongs to the parvalbumin family. (179 aa)
	TNRC6B	Trinucleotide repeat containing adaptor 6B. (1758 aa)
	RBFOX1	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. (423 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa)
	MECP2	Methyl-CpG binding protein 2. (537 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGCR8	MECP2	ENSMODP00000012948	ENSMODP00000014588	DGCR8 microprocessor complex subunit.	Methyl-CpG binding protein 2.	0.730
HDAC1	HDAC2	ENSMODP00000021783	ENSMODP00000022264	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
HDAC1	MECP2	ENSMODP00000021783	ENSMODP00000014588	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Methyl-CpG binding protein 2.	0.720
HDAC2	HDAC1	ENSMODP00000022264	ENSMODP00000021783	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
HDAC2	MECP2	ENSMODP00000022264	ENSMODP00000014588	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Methyl-CpG binding protein 2.	0.720
HIPK2	MECP2	ENSMODP00000017168	ENSMODP00000014588	Homeodomain interacting protein kinase 2.	Methyl-CpG binding protein 2.	0.737
HTT	MECP2	ENSMODP00000004422	ENSMODP00000014588	Huntingtin.	Methyl-CpG binding protein 2.	0.494
LBR	MECP2	ENSMODP00000007236	ENSMODP00000014588	Tudor domain-containing protein.	Methyl-CpG binding protein 2.	0.866
MECP2	DGCR8	ENSMODP00000014588	ENSMODP00000012948	Methyl-CpG binding protein 2.	DGCR8 microprocessor complex subunit.	0.730
MECP2	HDAC1	ENSMODP00000014588	ENSMODP00000021783	Methyl-CpG binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.720
MECP2	HDAC2	ENSMODP00000014588	ENSMODP00000022264	Methyl-CpG binding protein 2.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.720
MECP2	HIPK2	ENSMODP00000014588	ENSMODP00000017168	Methyl-CpG binding protein 2.	Homeodomain interacting protein kinase 2.	0.737
MECP2	HTT	ENSMODP00000014588	ENSMODP00000004422	Methyl-CpG binding protein 2.	Huntingtin.	0.494
MECP2	LBR	ENSMODP00000014588	ENSMODP00000007236	Methyl-CpG binding protein 2.	Tudor domain-containing protein.	0.866
MECP2	PVALB	ENSMODP00000014588	ENSMODP00000000934	Methyl-CpG binding protein 2.	Uncharacterized protein; Belongs to the parvalbumin family.	0.589
MECP2	RBFOX1	ENSMODP00000014588	ENSMODP00000048932	Methyl-CpG binding protein 2.	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events.	0.558
PVALB	MECP2	ENSMODP00000000934	ENSMODP00000014588	Uncharacterized protein; Belongs to the parvalbumin family.	Methyl-CpG binding protein 2.	0.589
RBFOX1	MECP2	ENSMODP00000048932	ENSMODP00000014588	RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events.	Methyl-CpG binding protein 2.	0.558