STRINGSTRING
TGFA TGFA MMP7 MMP7 GNG12 GNG12 GNB5 GNB5 PIK3R3 PIK3R3 XPO1 XPO1 ZDHHC7 ZDHHC7 CSDE1 CSDE1 GNG10 GNG10 AKT3 AKT3 GNB1 GNB1 WDR64 WDR64 AKT2 AKT2 GNG3 GNG3 EGFR EGFR GNG8 GNG8 ESR2 ESR2 HBEGF HBEGF F7GDN3_MONDO F7GDN3_MONDO S1PR3 S1PR3 PRMT1 PRMT1 HSPB1 HSPB1 AKT1 AKT1 MMP9 MMP9 ZDHHC21 ZDHHC21 STRN STRN CAV1 CAV1 PDPK1 PDPK1 ESR1 ESR1 GNG13 GNG13 GNAT3 GNAT3 GNAI1 GNAI1 STRN3 STRN3 GNB3 GNB3 EREG EREG AREG AREG PIK3R1 PIK3R1 GNB4 GNB4 PIK3CA PIK3CA NOS3 NOS3 EGF EGF KRAS-2 KRAS-2 GNG7 GNG7 GNG4 GNG4 PRMT8 PRMT8 GNAI2 GNAI2 SPHK1 SPHK1 CAV2 CAV2 STRN4 STRN4 ENSMODP00000046981 ENSMODP00000046981 GNGT2 GNGT2 UHMK1 UHMK1 NRAS NRAS GNG5 GNG5 ENSMODP00000051881 ENSMODP00000051881 PTK2 PTK2 EPGN EPGN ENSMODP00000053891 ENSMODP00000053891 LOC100010184 LOC100010184 KRAS KRAS GNB2 GNB2 IGF1R IGF1R ENSMODP00000059161 ENSMODP00000059161 CREB1 CREB1 ENSMODP00000059954 ENSMODP00000059954 HRAS HRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFATransforming growth factor alpha. (159 aa)
MMP7ZnMc domain-containing protein. (289 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB5G protein subunit beta 5. (353 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
XPO1Exportin 1. (1071 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (278 aa)
CSDE1Cold shock domain containing E1. (845 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GNB1G protein subunit beta 1. (340 aa)
WDR64WD repeat domain 64. (955 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
EGFRReceptor protein-tyrosine kinase. (1213 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ESR2Estrogen receptor 2. (533 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
F7GDN3_MONDOProtein kinase domain-containing protein. (317 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (390 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (256 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MMP9Matrix metallopeptidase 9. (709 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
STRNStriatin. (816 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (455 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNAT3G protein subunit alpha transducin 3. (335 aa)
GNAI1G protein subunit alpha i1. (354 aa)
STRN3Striatin 3. (801 aa)
GNB3G protein subunit beta 3. (340 aa)
EREGEpiregulin. (179 aa)
AREGAmphiregulin. (237 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
GNB4G protein subunit beta 4. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
EGFEpidermal growth factor. (1143 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (393 aa)
GNAI2G protein subunit alpha i2. (315 aa)
SPHK1Sphingosine kinase 1. (454 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
STRN4Striatin 4. (707 aa)
ENSMODP00000046981Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
UHMK1Uncharacterized protein. (419 aa)
NRASGTPase NRas. (195 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSMODP00000051881ETS domain-containing protein. (526 aa)
PTK2Uncharacterized protein. (161 aa)
EPGNEGF-like domain-containing protein. (152 aa)
ENSMODP00000053891Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (138 aa)
LOC100010184Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
KRASGTPase KRas. (189 aa)
GNB2G protein subunit beta 2. (367 aa)
IGF1RTyrosine-protein kinase receptor. (1259 aa)
ENSMODP00000059161FERM domain-containing protein. (121 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ENSMODP00000059954Uncharacterized protein. (554 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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