STRINGSTRING
GRB2 GRB2 DLG5 DLG5 NCK2 NCK2 WWP2 WWP2 HGS HGS EPHA2 EPHA2 STAM2 STAM2 GIT2 GIT2 PAK1 PAK1 ARHGAP30 ARHGAP30 PARD6A PARD6A F7CL95_MONDO F7CL95_MONDO RHOU RHOU STAM STAM CLTCL1 CLTCL1 PEAK1 PEAK1 WDR6 WDR6 ARHGEF6 ARHGEF6 F6T9J4_MONDO F6T9J4_MONDO PTK2B PTK2B PAK2 PAK2 NCK1 NCK1 DEPDC1B DEPDC1B PIK3R1 PIK3R1 USP9X USP9X F6VEG3_MONDO F6VEG3_MONDO MACF1 MACF1 CDC42 CDC42 F7CI75_MONDO F7CI75_MONDO CLTC CLTC ARHGAP31 ARHGAP31 PAK3 PAK3 ENSMODP00000043620 ENSMODP00000043620 TXNL1 TXNL1 ENSMODP00000047027 ENSMODP00000047027 DST DST ENSMODP00000051258 ENSMODP00000051258 ARHGEF7 ARHGEF7 ENSMODP00000053978 ENSMODP00000053978 PEAK3 PEAK3 ENSMODP00000057257 ENSMODP00000057257 MYO6 MYO6 SPTAN1 SPTAN1 ENSMODP00000059954 ENSMODP00000059954
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor bound protein 2. (217 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1938 aa)
NCK2Cytoplasmic protein. (380 aa)
WWP2E3 ubiquitin-protein ligase. (872 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (779 aa)
EPHA2EPH receptor A2. (886 aa)
STAM2Signal transducing adaptor molecule 2. (526 aa)
GIT2GIT ArfGAP 2. (770 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ARHGAP30Rho GTPase activating protein 30. (1136 aa)
PARD6APar-6 family cell polarity regulator alpha. (518 aa)
F7CL95_MONDOUncharacterized protein. (672 aa)
RHOURas homolog family member U. (268 aa)
STAMSignal transducing adaptor molecule. (526 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1556 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1689 aa)
WDR6WD_REPEATS_REGION domain-containing protein. (920 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (777 aa)
F6T9J4_MONDOUncharacterized protein. (191 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
PAK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
NCK1Cytoplasmic protein. (419 aa)
DEPDC1BDEP domain containing 1B. (523 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
USP9XUSP domain-containing protein; Belongs to the peptidase C19 family. (2553 aa)
F6VEG3_MONDOUncharacterized protein. (266 aa)
MACF1Microtubule actin crosslinking factor 1. (5353 aa)
CDC42Cell division cycle 42. (191 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
ARHGAP31Rho GTPase activating protein 31. (1321 aa)
PAK3Non-specific serine/threonine protein kinase. (632 aa)
ENSMODP00000043620Protein kinase domain-containing protein. (291 aa)
TXNL1Thioredoxin like 1. (292 aa)
ENSMODP00000047027VHS domain-containing protein. (70 aa)
DSTSH3 domain-containing protein. (2645 aa)
ENSMODP00000051258CRIB domain-containing protein. (122 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (869 aa)
ENSMODP00000053978Uncharacterized protein. (615 aa)
PEAK3Protein kinase domain-containing protein. (506 aa)
ENSMODP00000057257Uncharacterized protein. (66 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1278 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2510 aa)
ENSMODP00000059954Uncharacterized protein. (554 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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