10 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SQLE	Squalene epoxidase. (571 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (907 aa)
	ABCB11	ATP binding cassette subfamily B member 11. (1322 aa)
	CYP7B1	Uncharacterized protein; Belongs to the cytochrome P450 family. (462 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (505 aa)
	SLC10A1	Solute carrier family 10 member 1. (350 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (543 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (671 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (541 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB11	ABCG5	ENSMODP00000009711	ENSMODP00000000677	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 5.	0.474
ABCB11	ABCG8	ENSMODP00000009711	ENSMODP00000028394	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 8.	0.470
ABCB11	CYP27A1	ENSMODP00000009711	ENSMODP00000019193	ATP binding cassette subfamily B member 11.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.531
ABCB11	CYP7A1	ENSMODP00000009711	ENSMODP00000011028	ATP binding cassette subfamily B member 11.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.727
ABCB11	CYP7B1	ENSMODP00000009711	ENSMODP00000010212	ATP binding cassette subfamily B member 11.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.495
ABCB11	HMGCR	ENSMODP00000009711	ENSMODP00000002510	ATP binding cassette subfamily B member 11.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.464
ABCB11	SLC10A1	ENSMODP00000009711	ENSMODP00000014214	ATP binding cassette subfamily B member 11.	Solute carrier family 10 member 1.	0.766
ABCG5	ABCB11	ENSMODP00000000677	ENSMODP00000009711	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily B member 11.	0.474
ABCG5	ABCG8	ENSMODP00000000677	ENSMODP00000028394	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	CYP27A1	ENSMODP00000000677	ENSMODP00000019193	ATP binding cassette subfamily G member 5.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.512
ABCG5	CYP7A1	ENSMODP00000000677	ENSMODP00000011028	ATP binding cassette subfamily G member 5.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.715
ABCG5	CYP7B1	ENSMODP00000000677	ENSMODP00000010212	ATP binding cassette subfamily G member 5.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.572
ABCG5	HMGCR	ENSMODP00000000677	ENSMODP00000002510	ATP binding cassette subfamily G member 5.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.701
ABCG5	HMGCS1	ENSMODP00000000677	ENSMODP00000049665	ATP binding cassette subfamily G member 5.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.524
ABCG5	SLC10A1	ENSMODP00000000677	ENSMODP00000014214	ATP binding cassette subfamily G member 5.	Solute carrier family 10 member 1.	0.563
ABCG5	SQLE	ENSMODP00000000677	ENSMODP00000002212	ATP binding cassette subfamily G member 5.	Squalene epoxidase.	0.523
ABCG8	ABCB11	ENSMODP00000028394	ENSMODP00000009711	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily B member 11.	0.470
ABCG8	ABCG5	ENSMODP00000028394	ENSMODP00000000677	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	CYP27A1	ENSMODP00000028394	ENSMODP00000019193	ATP binding cassette subfamily G member 8.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.537
ABCG8	CYP7A1	ENSMODP00000028394	ENSMODP00000011028	ATP binding cassette subfamily G member 8.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.677