STRINGSTRING
HACD4 HACD4 RPL36 RPL36 EGF EGF STAT3 STAT3 ALDOB ALDOB ACO1 ACO1 PKM PKM F7EXF5_MONDO F7EXF5_MONDO STAT6 STAT6 F6TIT8_MONDO F6TIT8_MONDO IDH2 IDH2 ALDOC ALDOC HACD2 HACD2 PKLR PKLR ACO2 ACO2 IDH1 IDH1 ALDOA ALDOA HK2 HK2 HKDC1 HKDC1 HK1 HK1 RPL4 RPL4 PC PC FH FH HK3 HK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (217 aa)
RPL3660S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (93 aa)
EGFEpidermal growth factor. (1143 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (398 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (914 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (635 aa)
F7EXF5_MONDOFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (325 aa)
STAT6Signal transducer and activator of transcription. (839 aa)
F6TIT8_MONDOFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (304 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (416 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (569 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HK2Hexokinase 2. (932 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK1Hexokinase 1. (922 aa)
RPL4Ribosomal protein L4. (435 aa)
PCPyruvate carboxylase. (1322 aa)
FHFumarate hydratase. (504 aa)
HK3Hexokinase 3. (1049 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.