16 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL2	BCL2 apoptosis regulator. (188 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	RBX1	Uncharacterized protein. (120 aa)
	STAT3	Signal transducer and activator of transcription. (805 aa)
	SNAI1	Uncharacterized protein. (259 aa)
	CCND3	Cyclin D3; Belongs to the cyclin family. (300 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (275 aa)
	SPI1	Spi-1 proto-oncogene. (332 aa)
	SMURF2	E3 ubiquitin-protein ligase. (747 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
	LATS1	Large tumor suppressor kinase 1. (1151 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
	ELOC	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (126 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	CCND3	ENSMODP00000006458	ENSMODP00000051092	BCL2 apoptosis regulator.	Cyclin D3; Belongs to the cyclin family.	0.414
BCL2	ESR1	ENSMODP00000006458	ENSMODP00000020873	BCL2 apoptosis regulator.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.518
BCL2	STAT3	ENSMODP00000006458	ENSMODP00000052576	BCL2 apoptosis regulator.	Signal transducer and activator of transcription.	0.721
BCL2	TGFB1	ENSMODP00000006458	ENSMODP00000010737	BCL2 apoptosis regulator.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.403
CCND3	BCL2	ENSMODP00000051092	ENSMODP00000006458	Cyclin D3; Belongs to the cyclin family.	BCL2 apoptosis regulator.	0.414
ELOC	RBX1	ENSMODP00000008638	ENSMODP00000053954	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.999
ESR1	BCL2	ENSMODP00000020873	ENSMODP00000006458	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	BCL2 apoptosis regulator.	0.518
ESR1	STAT3	ENSMODP00000020873	ENSMODP00000052576	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Signal transducer and activator of transcription.	0.623
IDH1	IDH2	ENSMODP00000019879	ENSMODP00000024347	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.924
IDH2	IDH1	ENSMODP00000024347	ENSMODP00000019879	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.924
LATS1	SMURF2	ENSMODP00000020983	ENSMODP00000032216	Large tumor suppressor kinase 1.	E3 ubiquitin-protein ligase.	0.659
RBX1	ELOC	ENSMODP00000053954	ENSMODP00000008638	Uncharacterized protein.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.999
SMURF2	LATS1	ENSMODP00000032216	ENSMODP00000020983	E3 ubiquitin-protein ligase.	Large tumor suppressor kinase 1.	0.659
SMURF2	TGFB1	ENSMODP00000032216	ENSMODP00000010737	E3 ubiquitin-protein ligase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.600
STAT3	BCL2	ENSMODP00000052576	ENSMODP00000006458	Signal transducer and activator of transcription.	BCL2 apoptosis regulator.	0.721
STAT3	ESR1	ENSMODP00000052576	ENSMODP00000020873	Signal transducer and activator of transcription.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.623
STAT3	TGFB1	ENSMODP00000052576	ENSMODP00000010737	Signal transducer and activator of transcription.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.505
TGFB1	BCL2	ENSMODP00000010737	ENSMODP00000006458	Transforming growth factor beta; Belongs to the TGF-beta family.	BCL2 apoptosis regulator.	0.403
TGFB1	SMURF2	ENSMODP00000010737	ENSMODP00000032216	Transforming growth factor beta; Belongs to the TGF-beta family.	E3 ubiquitin-protein ligase.	0.600
TGFB1	STAT3	ENSMODP00000010737	ENSMODP00000052576	Transforming growth factor beta; Belongs to the TGF-beta family.	Signal transducer and activator of transcription.	0.505