(45 nodes) Low-density lipoprotein receptor domain class A network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRP10	LDL receptor related protein 10. (710 aa)
	SPINT1	Serine peptidase inhibitor, Kunitz type 1. (596 aa)
	LRP8	LDL receptor related protein 8. (854 aa)
	F6WZ75_MONDO	Uncharacterized protein. (128 aa)
	RXFP1	Relaxin family peptide receptor 1. (745 aa)
	SSPO	SCO-spondin. (4867 aa)
	LRP1B	LDL receptor related protein 1B. (4599 aa)
	ST14	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
	LRP1	LDL receptor related protein 1. (3492 aa)
	VLDLR	Very low density lipoprotein receptor. (868 aa)
	C8A	Complement C8 alpha chain. (580 aa)
	CD320	Uncharacterized protein. (314 aa)
	TMPRSS15	Transmembrane serine protease 15; Belongs to the peptidase S1 family. (1053 aa)
	TMPRSS9	Transmembrane serine protease 9; Belongs to the peptidase S1 family. (1070 aa)
	RXFP2	Relaxin family peptide receptor 2. (710 aa)
	LDLRAD1	Low density lipoprotein receptor class A domain containing 1. (207 aa)
	TMPRSS13	Transmembrane serine protease 13; Belongs to the peptidase S1 family. (501 aa)
	TMPRSS6	Transmembrane serine protease 6; Belongs to the peptidase S1 family. (820 aa)
	LRP12	LDL receptor related protein 12. (858 aa)
	F6YTA8_MONDO	MACPF domain-containing protein. (539 aa)
	CFI	Uncharacterized protein; Belongs to the peptidase S1 family. (601 aa)
	LDLRAD3	Low density lipoprotein receptor class A domain containing 3. (345 aa)
	DGCR2	DiGeorge syndrome critical region gene 2. (556 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (292 aa)
	TMPRSS3	Transmembrane serine protease 3; Belongs to the peptidase S1 family. (422 aa)
	TMPRSS2	Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)
	CORIN	Corin, serine peptidase. (1111 aa)
	C9	Complement C9. (620 aa)
	C7	Complement C7. (836 aa)
	C6	Complement C6. (933 aa)
	LRP4	LDL receptor related protein 4. (1908 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	TMPRSS7	Transmembrane serine protease 7; Belongs to the peptidase S1 family. (827 aa)
	MAMDC4	MAM domain containing 4. (1227 aa)
	LRP11	LDL receptor related protein 11. (533 aa)
	HSPG2	Heparan sulfate proteoglycan 2. (4361 aa)
	LOC100031528	Uncharacterized protein; Belongs to the peptidase S1 family. (418 aa)
	SORL1	Sortilin related receptor 1. (2218 aa)
	NETO2	Neuropilin and tolloid like 2. (525 aa)
	NETO1	Neuropilin and tolloid like 1. (521 aa)
	LRP3	LDL receptor related protein 3. (897 aa)
	MALRD1	MAM and LDL receptor class A domain containing 1. (2125 aa)
	LRP2	LDL receptor related protein 2. (4605 aa)
	PRKCSH	Protein kinase C substrate 80K-H. (536 aa)
	LDLR	Low density lipoprotein receptor. (906 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C6	C7	ENSMODP00000025382	ENSMODP00000025394	Complement C6.	Complement C7.	0.993
C6	C8A	ENSMODP00000025382	ENSMODP00000054794	Complement C6.	Complement C8 alpha chain.	0.948
C6	C9	ENSMODP00000025382	ENSMODP00000025406	Complement C6.	Complement C9.	0.994
C6	F6YTA8_MONDO	ENSMODP00000025382	ENSMODP00000037028	Complement C6.	MACPF domain-containing protein.	0.744
C7	C6	ENSMODP00000025394	ENSMODP00000025382	Complement C7.	Complement C6.	0.993
C7	C8A	ENSMODP00000025394	ENSMODP00000054794	Complement C7.	Complement C8 alpha chain.	0.949
C7	C9	ENSMODP00000025394	ENSMODP00000025406	Complement C7.	Complement C9.	0.987
C7	F6YTA8_MONDO	ENSMODP00000025394	ENSMODP00000037028	Complement C7.	MACPF domain-containing protein.	0.742
C8A	C6	ENSMODP00000054794	ENSMODP00000025382	Complement C8 alpha chain.	Complement C6.	0.948
C8A	C7	ENSMODP00000054794	ENSMODP00000025394	Complement C8 alpha chain.	Complement C7.	0.949
C8A	C9	ENSMODP00000054794	ENSMODP00000025406	Complement C8 alpha chain.	Complement C9.	0.957
C8A	F6YTA8_MONDO	ENSMODP00000054794	ENSMODP00000037028	Complement C8 alpha chain.	MACPF domain-containing protein.	0.795
C9	C6	ENSMODP00000025406	ENSMODP00000025382	Complement C9.	Complement C6.	0.994
C9	C7	ENSMODP00000025406	ENSMODP00000025394	Complement C9.	Complement C7.	0.987
C9	C8A	ENSMODP00000025406	ENSMODP00000054794	Complement C9.	Complement C8 alpha chain.	0.957
C9	CFI	ENSMODP00000025406	ENSMODP00000036977	Complement C9.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.551
C9	F6YTA8_MONDO	ENSMODP00000025406	ENSMODP00000037028	Complement C9.	MACPF domain-containing protein.	0.724
CD320	HSPG2	ENSMODP00000052684	ENSMODP00000020041	Uncharacterized protein.	Heparan sulfate proteoglycan 2.	0.416
CFI	C9	ENSMODP00000036977	ENSMODP00000025406	Uncharacterized protein; Belongs to the peptidase S1 family.	Complement C9.	0.551
DGCR2	HSPG2	ENSMODP00000030146	ENSMODP00000020041	DiGeorge syndrome critical region gene 2.	Heparan sulfate proteoglycan 2.	0.416