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LOC100018520 LOC100018520 LOC100010821 LOC100010821 SDHA SDHA PKM PKM PDHB PDHB ACSS2 ACSS2 PGD PGD EHHADH EHHADH FBP2 FBP2 ACADS ACADS ACOX3 ACOX3 SUCLG2 SUCLG2 SDS SDS GOT1 GOT1 SDSL SDSL HAO1 HAO1 PGK1 PGK1 PGAM1 PGAM1 PGLS PGLS HK3 HK3 ENO3 ENO3 PHGDH PHGDH DLST DLST ALDH6A1 ALDH6A1 PSPH PSPH FH FH ACAT2 ACAT2 ACOX1 ACOX1 PC PC IDH3G IDH3G G6PD G6PD ENO4 ENO4 ENO1 ENO1 RPIA RPIA ADPGK ADPGK ECHS1 ECHS1 HK1 HK1 HKDC1 HKDC1 GOT1L1 GOT1L1 ME2 ME2 GPT GPT SUCLA2 SUCLA2 ESD ESD HK2 HK2 HIBCH HIBCH IDH3A IDH3A TKTL2 TKTL2 GPI GPI TKT TKT PSAT1 PSAT1 AMT AMT F7EDE1_MONDO F7EDE1_MONDO MDH2 MDH2 LOC100014432 LOC100014432 GOT2 GOT2 ACAT1 ACAT1 GLDC GLDC ALDOA ALDOA RPE RPE IDH1 IDH1 OGDH OGDH DLD DLD ACO2 ACO2 PKLR PKLR PRPS2 PRPS2 TPI1 TPI1 ME1 ME1 MMUT MMUT ALDOC ALDOC IDH2 IDH2 TKFC TKFC LOC100014996 LOC100014996 PGP PGP SUCLG1 SUCLG1 LOC100031601 LOC100031601 F6U684_MONDO F6U684_MONDO OGDHL OGDHL LOC100014733 LOC100014733 LOC100011551 LOC100011551 GAPDH GAPDH GLYCTK GLYCTK DLAT DLAT CPS1 CPS1 IDNK IDNK SDHC SDHC PDHA1 PDHA1 GCK GCK AGXT AGXT ME3 ME3 ENSMODP00000049567 ENSMODP00000049567 ENSMODP00000051936 ENSMODP00000051936 MTHFR MTHFR CAT CAT MDH1 MDH1 H6PD H6PD ALDOB ALDOB HAO2 HAO2 GPT2 GPT2 SDHB SDHB PCCA PCCA SDHD SDHD HADHA HADHA ACSS1 ACSS1 SHMT1 SHMT1 FBP1 FBP1 ACO1 ACO1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC100018520Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
LOC100010821SGL domain-containing protein. (299 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (635 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (371 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (801 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (697 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (340 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (541 aa)
SDSSerine dehydratase. (218 aa)
GOT1Aspartate aminotransferase. (466 aa)
SDSLSerine dehydratase like. (334 aa)
HAO1Hydroxyacid oxidase 1. (374 aa)
PGK1Phosphoglycerate kinase. (417 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (263 aa)
HK3Hexokinase 3. (1049 aa)
ENO3Enolase 3. (434 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (561 aa)
PSPHPhosphoserine phosphatase. (226 aa)
FHFumarate hydratase. (504 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ACOX1Acyl-CoA_ox_N domain-containing protein. (203 aa)
PCPyruvate carboxylase. (1322 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (616 aa)
ENO4Enolase 4. (604 aa)
ENO1Uncharacterized protein. (405 aa)
RPIARibose 5-phosphate isomerase A. (334 aa)
ADPGKADP dependent glucokinase. (487 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
HK1Hexokinase 1. (922 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (446 aa)
ME2Malic enzyme. (584 aa)
GPTGlutamic--pyruvic transaminase. (487 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (464 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
HK2Hexokinase 2. (932 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
TKTL2Transketolase like 2. (664 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (705 aa)
TKTTransketolase. (628 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (373 aa)
F7EDE1_MONDOMalic enzyme. (569 aa)
MDH2Malate dehydrogenase. (338 aa)
LOC100014432Pribosyltran_N domain-containing protein. (324 aa)
GOT2Aspartate aminotransferase. (429 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1033 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
DLDDihydrolipoyl dehydrogenase. (468 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (569 aa)
PRPS2Pribosyltran_N domain-containing protein. (321 aa)
TPI1Triosephosphate isomerase. (249 aa)
ME1Malic enzyme. (692 aa)
MMUTMethylmalonyl-CoA mutase. (750 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
TKFCTriokinase and FMN cyclase. (765 aa)
LOC100014996Phosphoglycerate kinase. (417 aa)
PGPPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (322 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (371 aa)
LOC100031601Phosphoglycerate kinase. (417 aa)
F6U684_MONDOPhosphoglycerate kinase. (397 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
LOC100014733Phosphoglycerate kinase. (417 aa)
LOC100011551SGL domain-containing protein. (299 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (360 aa)
GLYCTKGlycerate kinase. (522 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
CPS1Carbamoyl-phosphate synthase 1. (1525 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (184 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
GCKPhosphotransferase. (532 aa)
AGXTAlanine--glyoxylate and serine--pyruvate aminotransferase. (393 aa)
ME3Malic enzyme; Belongs to the malic enzymes family. (610 aa)
ENSMODP00000049567Uncharacterized protein. (450 aa)
ENSMODP00000051936Uncharacterized protein. (202 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (684 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (529 aa)
MDH1Malate dehydrogenase. (356 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (398 aa)
HAO2Hydroxyacid oxidase 2. (406 aa)
GPT2Glutamic--pyruvic transaminase 2. (640 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (744 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (790 aa)
ACSS1Acyl-CoA synthetase short chain family member 1. (672 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
FBP1FBPase domain-containing protein; Belongs to the FBPase class 1 family. (338 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (914 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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