66 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DBI	ACB domain-containing protein. (63 aa)
	CPT2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (666 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (552 aa)
	MMP1	Matrix metallopeptidase 1. (469 aa)
	PLIN5	Perilipin; Belongs to the perilipin family. (443 aa)
	F7G7K9_MONDO	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (200 aa)
	RXRG	Retinoid X receptor gamma. (467 aa)
	F7BCH7_MONDO	AMP-binding domain-containing protein. (651 aa)
	LOC100023663	Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
	SLC27A2	Solute carrier family 27 member 2. (620 aa)
	LOC100018582	Uncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (697 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
	CPT1A	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (300 aa)
	SLC27A1	Solute carrier family 27 member 1. (647 aa)
	SLC27A4	Solute carrier family 27 member 4. (649 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (486 aa)
	FABP5	Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	LOC100009895	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (224 aa)
	ACOX1	Acyl-CoA_ox_N domain-containing protein. (203 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (505 aa)
	FABP1	FABP domain-containing protein. (86 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (479 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (683 aa)
	SCD	Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (363 aa)
	SCD5	Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (333 aa)
	F7EDE1_MONDO	Malic enzyme. (569 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (256 aa)
	CPT1C	Carn_acyltransf domain-containing protein. (1233 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	ACSL6	AMP-binding domain-containing protein. (725 aa)
	RXRB	Retinoid X receptor beta. (530 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (445 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (543 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (433 aa)
	LOC100021198	Uncharacterized protein. (761 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (471 aa)
	FABP7	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	ME1	Malic enzyme. (692 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (617 aa)
	LOC100010920	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (683 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (431 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	F7D822_MONDO	ACB domain-containing protein. (59 aa)
	ANGPTL4	Angiopoietin like 4. (454 aa)
	PLIN4	Uncharacterized protein. (1955 aa)
	PLIN1	Perilipin 1. (544 aa)
	ACADM	Acyl-CoA dehydrogenase medium chain. (409 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (341 aa)
	K7E416_MONDO	Uncharacterized protein. (596 aa)
	APOC3	Uncharacterized protein. (100 aa)
	SLC27A5	Solute carrier family 27 member 5. (686 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (737 aa)
	ENSMODP00000045933	AMP-binding domain-containing protein. (654 aa)
	ILK	Integrin linked kinase. (486 aa)
	ME3	Malic enzyme; Belongs to the malic enzymes family. (610 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (541 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (553 aa)
	CPT1B	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (775 aa)
	FABP6	Uncharacterized protein. (143 aa)
	APOA5	Apolipoprotein A5. (370 aa)
	FABP3	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (216 aa)
	APOA1	Uncharacterized protein. (264 aa)
	ACSBG1	Acyl-CoA synthetase bubblegum family member 1. (739 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACADL	ENSMODP00000026454	ENSMODP00000019737	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA dehydrogenase long chain.	0.972
ACAA1	ACADM	ENSMODP00000026454	ENSMODP00000038188	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA dehydrogenase medium chain.	0.958
ACAA1	ACOX1	ENSMODP00000026454	ENSMODP00000009713	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA_ox_N domain-containing protein.	0.986
ACAA1	ACOX2	ENSMODP00000026454	ENSMODP00000024469	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.870
ACAA1	ACOX3	ENSMODP00000026454	ENSMODP00000003841	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.975
ACAA1	ACSBG1	ENSMODP00000026454	ENSMODP00000059951	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase bubblegum family member 1.	0.471
ACAA1	ACSL1	ENSMODP00000026454	ENSMODP00000045703	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 1.	0.532
ACAA1	ACSL3	ENSMODP00000026454	ENSMODP00000026491	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 3.	0.487
ACAA1	ACSL5	ENSMODP00000026454	ENSMODP00000012865	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 5.	0.483
ACAA1	ACSL6	ENSMODP00000026454	ENSMODP00000017612	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	AMP-binding domain-containing protein.	0.476
ACAA1	CPT2	ENSMODP00000026454	ENSMODP00000000567	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.	0.487
ACAA1	DBI	ENSMODP00000026454	ENSMODP00000000472	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	ACB domain-containing protein.	0.518
ACAA1	EHHADH	ENSMODP00000026454	ENSMODP00000003242	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.	0.990
ACAA1	ENSMODP00000045933	ENSMODP00000026454	ENSMODP00000045933	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	AMP-binding domain-containing protein.	0.471
ACAA1	F7BCH7_MONDO	ENSMODP00000026454	ENSMODP00000001733	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	AMP-binding domain-containing protein.	0.471
ACAA1	F7D822_MONDO	ENSMODP00000026454	ENSMODP00000028722	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	ACB domain-containing protein.	0.518
ACAA1	F7EDE1_MONDO	ENSMODP00000026454	ENSMODP00000016545	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Malic enzyme.	0.414
ACAA1	HMGCS1	ENSMODP00000026454	ENSMODP00000049665	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.984
ACAA1	HMGCS2	ENSMODP00000026454	ENSMODP00000040002	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.984
ACAA1	K7E416_MONDO	ENSMODP00000026454	ENSMODP00000040518	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.474