STRINGSTRING
GNA12 GNA12 PTPN7 PTPN7 RAC2 RAC2 PPM1B PPM1B GNG12 GNG12 GADD45A GADD45A PDGFD PDGFD MAPK7 MAPK7 GADD45G GADD45G RAP1A RAP1A PDGFC PDGFC MYC MYC ELK4 ELK4 MKNK1 MKNK1 IGF1 IGF1 RPS6KA5 RPS6KA5 MAP3K13 MAP3K13 RAC3 RAC3 JUN JUN VEGFC VEGFC FGF16 FGF16 CACNG1 CACNG1 FGF19 FGF19 FGF4 FGF4 PRKCA PRKCA TEK TEK TGFB2 TGFB2 CASP3 CASP3 MKNK2 MKNK2 DUSP10 DUSP10 NGF NGF PAK1 PAK1 ANGPT1 ANGPT1 TGFB3 TGFB3 HSPA1A HSPA1A FOS FOS MAPK8IP2 MAPK8IP2 TRADD TRADD RAF1 RAF1 PTPN5 PTPN5 MAP2K6 MAP2K6 AKT3 AKT3 ECSIT ECSIT RAP1B RAP1B GRB2 GRB2 AKT2 AKT2 MAP3K8 MAP3K8 RPS6KA3 RPS6KA3 DUSP9 DUSP9 DUSP2 DUSP2 FGFR2 FGFR2 TGFB1 TGFB1 SOS1 SOS1 EGFR EGFR FLT1 FLT1 MAP3K20 MAP3K20 IKBKG IKBKG PPP5C PPP5C ATF4 ATF4 TAB1 TAB1 PPP3CC PPP3CC ATF2 ATF2 MAP2K5 MAP2K5 PDGFB PDGFB RELA RELA FGF17 FGF17 MAP2K1 MAP2K1 PDGFRB PDGFRB CSF1R CSF1R CACNB3 CACNB3 IKBKB IKBKB CHUK CHUK FGFR1 FGFR1 TGFA TGFA DUSP7 DUSP7 SOS2 SOS2 MAPKAPK3 MAPKAPK3 ANGPT2 ANGPT2 MAPKAPK5 MAPKAPK5 TGFBR1 TGFBR1 CACNB1 CACNB1 MAP4K1 MAP4K1 PLA2G4C PLA2G4C HSPB1 HSPB1 MAPK13 MAPK13 AKT1 AKT1 NTF4 NTF4 IL1B IL1B STMN1 STMN1 DAXX DAXX RPS6KA6 RPS6KA6 MAP3K6 MAP3K6 MAP2K7 MAP2K7 FLNC FLNC INSR INSR TGFBR2 TGFBR2 TAOK3 TAOK3 RASGRP3 RASGRP3 MAPK3 MAPK3 ERBB4 ERBB4 MET MET MAPK8IP3 MAPK8IP3 CACNG3 CACNG3 HGF HGF EFNA4 EFNA4 VEGFD VEGFD TRAF2 TRAF2 MAP3K5 MAP3K5 CRKL CRKL MAPK1 MAPK1 PLA2G4E PLA2G4E TNFRSF1A TNFRSF1A DUSP16 DUSP16 FGF23 FGF23 CACNA2D4 CACNA2D4 PAK2 PAK2 IRAK4 IRAK4 MRAS MRAS MAP3K2 MAP3K2 FGF2 FGF2 VEGFA VEGFA SRF SRF DUSP4 DUSP4 FGF20 FGF20 F7FNN8_MONDO F7FNN8_MONDO EREG EREG AREG AREG DUSP8 DUSP8 TAOK1 TAOK1 RASGRF1 RASGRF1 MAP3K1 MAP3K1 TRAF6 TRAF6 RASGRF2 RASGRF2 PTPRR PTPRR DUSP6 DUSP6 PDGFRA PDGFRA NFKB1 NFKB1 KDR KDR PPP3CA PPP3CA LAMTOR3 LAMTOR3 MAPK10 MAPK10 FGF5 FGF5 LOC100017469 LOC100017469 RELB RELB RASA2 RASA2 CSF1 CSF1 MAPK9 MAPK9 CD14 CD14 CDC42 CDC42 F7CI75_MONDO F7CI75_MONDO EFNA3 EFNA3 BRAF BRAF NTRK2 NTRK2 CACNA1S CACNA1S KIT KIT LOC100011711 LOC100011711 LOC100015032 LOC100015032 EGF EGF KRAS-2 KRAS-2 NGFR NGFR MAP3K14 MAP3K14 FGF3 FGF3 EFNA5 EFNA5 EFNA2 EFNA2 MAP2K3 MAP2K3 STK3 STK3 NFATC3 NFATC3 FGFR4 FGFR4 MAX MAX MAP3K11 MAP3K11 FLNA FLNA MAP3K4 MAP3K4 CACNA1A CACNA1A PPP3CB PPP3CB PRKCB PRKCB KITLG KITLG RPS6KA2 RPS6KA2 BDNF BDNF PDGFA PDGFA RASA1 RASA1 RPS6KA1 RPS6KA1 LOC654275 LOC654275 FLT4 FLT4 NFATC1 NFATC1 RRAS RRAS MAP3K7 MAP3K7 MAPK14 MAPK14 CACNA2D2 CACNA2D2 PGF PGF NRAS NRAS PRKACA PRKACA EFNA1 EFNA1 RRAS2 RRAS2 STK4 STK4 ERBB3 ERBB3 ARAF ARAF FGF1 FGF1 FLT3 FLT3 ANGPT4 ANGPT4 CACNB2 CACNB2 FGF6 FGF6 TAOK2 TAOK2 RASGRP1 RASGRP1 MAPK8IP1 MAPK8IP1 ERBB2 ERBB2 MAP4K3 MAP4K3 RASGRP4 RASGRP4 CACNA1C CACNA1C CACNA2D3 CACNA2D3 NLK NLK DUSP5 DUSP5 MAPK12 MAPK12 TAB2 TAB2 IL1R1 IL1R1 FGF9 FGF9 HSPA8 HSPA8 RAPGEF2 RAPGEF2 LOC100010184 LOC100010184 SIRT6 SIRT6 FGF10 FGF10 CACNA2D1-2 CACNA2D1-2 CACNA1H CACNA1H DUSP1 DUSP1 PPM1A PPM1A FGF18 FGF18 NF1 NF1 MAP3K3 MAP3K3 ENSMODP00000058393 ENSMODP00000058393 MAPT MAPT IGF1R IGF1R CACNB4 CACNB4 CACNA1G CACNA1G F7GAG3_MONDO F7GAG3_MONDO FGF7 FGF7 NTF3 NTF3 HRAS HRAS VEGFB VEGFB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GNA12G protein subunit alpha 12. (380 aa)
PTPN7Protein tyrosine phosphatase non-receptor type 7. (335 aa)
RAC2Rac family small GTPase 2. (281 aa)
PPM1BPPM-type phosphatase domain-containing protein. (480 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (168 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (778 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
RAP1AUncharacterized protein. (177 aa)
PDGFCPlatelet derived growth factor C. (345 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
ELK4ETS transcription factor ELK4. (432 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (423 aa)
IGF1Insulin like growth factor 1. (225 aa)
RPS6KA5Ribosomal protein S6 kinase. (795 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (964 aa)
RAC3Rac family small GTPase 3. (192 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (351 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (453 aa)
DUSP10Dual specificity phosphatase 10. (482 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (238 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ANGPT1Angiopoietin 1. (498 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (722 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (991 aa)
TRADDTNFRSF1A associated via death domain. (361 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
PTPN5Protein tyrosine phosphatase non-receptor type 5. (567 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ECSITECSIT signalling integrator. (460 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (397 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (316 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
EGFRReceptor protein-tyrosine kinase. (1213 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (805 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
PPP5CSerine/threonine-protein phosphatase. (406 aa)
ATF4Activating transcription factor 4. (346 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (652 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PDGFRBPlatelet derived growth factor receptor beta. (1061 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (959 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (482 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
FGFR1Fibroblast growth factor receptor. (809 aa)
TGFATransforming growth factor alpha. (159 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (378 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1328 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (395 aa)
ANGPT2Angiopoietin 2. (495 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (605 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
PLA2G4CPLA2c domain-containing protein. (204 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (256 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (249 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
STMN1Stathmin; Belongs to the stathmin family. (149 aa)
DAXXDeath domain associated protein. (739 aa)
RPS6KA6Ribosomal protein S6 kinase. (771 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1273 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
FLNCFilamin C. (2653 aa)
INSRTyrosine-protein kinase receptor. (1378 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
TAOK3Uncharacterized protein. (438 aa)
RASGRP3RAS guanyl releasing protein 3. (647 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1387 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1323 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (217 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1390 aa)
CRKLUncharacterized protein. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PLA2G4EPhospholipase A2. (868 aa)
TNFRSF1AUncharacterized protein. (453 aa)
DUSP16Dual specificity phosphatase 16. (660 aa)
FGF23Fibroblast growth factor 23. (193 aa)
CACNA2D4VWFA domain-containing protein. (330 aa)
PAK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (619 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa)
SRFSerum response factor. (490 aa)
DUSP4Tyrosine-protein phosphatase domain-containing protein. (226 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
F7FNN8_MONDOUncharacterized protein. (199 aa)
EREGEpiregulin. (179 aa)
AREGAmphiregulin. (237 aa)
DUSP8DSPc domain-containing protein. (323 aa)
TAOK1TAO kinase 1. (999 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1256 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1491 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1240 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1085 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
FGF5Uncharacterized protein. (125 aa)
LOC100017469Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1570 aa)
RELBRELB proto-oncogene, NF-kB subunit. (621 aa)
RASA2RAS p21 protein activator 2. (849 aa)
CSF1Uncharacterized protein. (340 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CD14Uncharacterized protein. (382 aa)
CDC42Cell division cycle 42. (191 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
NTRK2Tyrosine-protein kinase receptor. (750 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
LOC100011711Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
LOC100015032Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
EGFEpidermal growth factor. (1143 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
NGFRNerve growth factor receptor. (433 aa)
MAP3K14Uncharacterized protein. (1744 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (254 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (200 aa)
MAP2K3Mitogen-activated protein kinase kinase 3. (239 aa)
STK3Serine/threonine kinase 3. (555 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
FGFR4Fibroblast growth factor receptor. (849 aa)
MAXBHLH domain-containing protein. (187 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (859 aa)
FLNAFilamin A. (2558 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1621 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2485 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (285 aa)
PDGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
RASA1RAS p21 protein activator 1. (1022 aa)
RPS6KA1Ribosomal protein S6 kinase. (740 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
NFATC1Nuclear factor of activated T cells 1. (950 aa)
RRASRAS related. (255 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CACNA2D2Uncharacterized protein. (484 aa)
PGFPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (207 aa)
NRASGTPase NRas. (195 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (267 aa)
RRAS2Uncharacterized protein. (200 aa)
STK4Serine/threonine kinase 4. (496 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1343 aa)
ARAFUncharacterized protein. (198 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
ANGPT4Angiopoietin 4. (495 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
TAOK2TAO kinase 2. (1248 aa)
RASGRP1RAS guanyl releasing protein 1. (861 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (646 aa)
ERBB2Receptor protein-tyrosine kinase. (1257 aa)
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)
RASGRP4RAS guanyl releasing protein 4. (753 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (997 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (529 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
IL1R1TIR domain-containing protein. (344 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (648 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1703 aa)
LOC100010184Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
SIRT6Uncharacterized protein. (547 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
CACNA2D1-2Uncharacterized protein. (105 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2358 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (422 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
NF1Neurofibromin 1. (2781 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (667 aa)
ENSMODP00000058393Arrestin_N domain-containing protein. (120 aa)
MAPTMicrotubule-associated protein. (1051 aa)
IGF1RTyrosine-protein kinase receptor. (1259 aa)
CACNB4SH3 domain-containing protein. (520 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2345 aa)
F7GAG3_MONDOPLA2c domain-containing protein. (590 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (343 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (568 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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