86 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LBP	Lipopolysaccharide binding protein. (483 aa)
	CARD10	Uncharacterized protein. (346 aa)
	LOC100010741	CARD domain-containing protein. (585 aa)
	BIRC2	Uncharacterized protein. (383 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
	PIAS4	Protein inhibitor of activated STAT 4. (494 aa)
	GADD45A	Growth arrest and DNA damage inducible alpha. (168 aa)
	TICAM1	TRIF-NTD domain-containing protein. (713 aa)
	GADD45G	Growth arrest and DNA damage inducible gamma. (159 aa)
	CARD14	Caspase recruitment domain family member 14. (973 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa)
	EDAR	Ectodysplasin A receptor. (448 aa)
	ZAP70	Tyrosine-protein kinase. (619 aa)
	VCAM1	Vascular cell adhesion molecule 1. (743 aa)
	TIRAP	TIR domain-containing protein. (342 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (426 aa)
	BLNK	B cell linker. (466 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (286 aa)
	TNFRSF11A	TNFR-Cys domain-containing protein. (670 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
	TRADD	TNFRSF1A associated via death domain. (361 aa)
	CCL21	C-C motif chemokine ligand 21. (138 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (706 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (652 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (543 aa)
	CXCL12	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	BTK	Tyrosine-protein kinase. (655 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (608 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	TICAM2	TIR domain-containing protein. (223 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
	TRIM25	Tripartite motif containing 25. (672 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	XIAP	X-linked inhibitor of apoptosis. (498 aa)
	PIDD1	Uncharacterized protein. (272 aa)
	CFLAR	Uncharacterized protein. (266 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
	LTB	Lymphotoxin beta; Belongs to the tumor necrosis factor family. (251 aa)
	LTA	Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (231 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
	TNFAIP3	TNF alpha induced protein 3. (796 aa)
	LCK	Tyrosine-protein kinase. (686 aa)
	TNFRSF1A	Uncharacterized protein. (453 aa)
	LTBR	Lymphotoxin beta receptor. (431 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (458 aa)
	LOC103099606	C-C motif chemokine. (95 aa)
	LOC100020842	C-C motif chemokine. (156 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	BCL2A1	BCL2 related protein A1. (172 aa)
	BCL2L1	BCL2 like 1. (227 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (995 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (621 aa)
	TRAF1	TNF receptor-associated factor. (380 aa)
	CD14	Uncharacterized protein. (382 aa)
	EDARADD	Death domain-containing protein. (290 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (1053 aa)
	CCL19	C-C motif chemokine. (96 aa)
	LY96	ML domain-containing protein. (157 aa)
	LOC100017283	C-C motif chemokine. (91 aa)
	LOC100017328	C-C motif chemokine. (95 aa)
	K7DYV5_MONDO	Ig-like domain-containing protein. (295 aa)
	MAP3K14	Uncharacterized protein. (1744 aa)
	CSNK2A2	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (392 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
	CYLD	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (251 aa)
	CSNK2B	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
	BCL10	CARD domain-containing protein. (245 aa)
	UBE2I	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (224 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
	IL1R1	TIR domain-containing protein. (344 aa)
	CARD11	Caspase recruitment domain family member 11. (1176 aa)
	NFKBIA	ANK_REP_REGION domain-containing protein. (400 aa)
	SYK	Tyrosine-protein kinase. (588 aa)
	F7BIP4_MONDO	Ig-like domain-containing protein. (182 aa)
	LYN	Tyrosine-protein kinase. (516 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (722 aa)
	ATM	TAN domain-containing protein. (112 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	CHUK	ENSMODP00000059879	ENSMODP00000013213	TAN domain-containing protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.401
ATM	IKBKB	ENSMODP00000059879	ENSMODP00000012792	TAN domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.401
ATM	IKBKG	ENSMODP00000059879	ENSMODP00000011449	TAN domain-containing protein.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.618
ATM	MAP3K7	ENSMODP00000059879	ENSMODP00000047628	TAN domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.456
ATM	PARP1	ENSMODP00000059879	ENSMODP00000007535	TAN domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.598
ATM	PIAS4	ENSMODP00000059879	ENSMODP00000000916	TAN domain-containing protein.	Protein inhibitor of activated STAT 4.	0.840
ATM	PIDD1	ENSMODP00000059879	ENSMODP00000018737	TAN domain-containing protein.	Uncharacterized protein.	0.711
ATM	UBE2I	ENSMODP00000059879	ENSMODP00000052211	TAN domain-containing protein.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.594
BCL10	BIRC2	ENSMODP00000052151	ENSMODP00000000728	CARD domain-containing protein.	Uncharacterized protein.	0.434
BCL10	CARD10	ENSMODP00000052151	ENSMODP00000000694	CARD domain-containing protein.	Uncharacterized protein.	0.821
BCL10	CARD11	ENSMODP00000052151	ENSMODP00000054644	CARD domain-containing protein.	Caspase recruitment domain family member 11.	0.993
BCL10	CARD14	ENSMODP00000052151	ENSMODP00000002694	CARD domain-containing protein.	Caspase recruitment domain family member 14.	0.790
BCL10	CHUK	ENSMODP00000052151	ENSMODP00000013213	CARD domain-containing protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.975
BCL10	IKBKB	ENSMODP00000052151	ENSMODP00000012792	CARD domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.981
BCL10	IKBKG	ENSMODP00000052151	ENSMODP00000011449	CARD domain-containing protein.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.978
BCL10	LOC100010741	ENSMODP00000052151	ENSMODP00000000705	CARD domain-containing protein.	CARD domain-containing protein.	0.434
BCL10	MAP3K7	ENSMODP00000052151	ENSMODP00000047628	CARD domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.959
BCL10	NFKB1	ENSMODP00000052151	ENSMODP00000025861	CARD domain-containing protein.	Nuclear factor kappa B subunit 1.	0.683
BCL10	NFKBIA	ENSMODP00000052151	ENSMODP00000054754	CARD domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.568
BCL10	PRKCQ	ENSMODP00000052151	ENSMODP00000020799	CARD domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.820