STRINGSTRING
PLA2G12B PLA2G12B GNA12 GNA12 PLCB2 PLCB2 EDNRA EDNRA PRKCE PRKCE MYH9 MYH9 ADCY8 ADCY8 GUCY1A1 GUCY1A1 LOC100023663 LOC100023663 AVPR1B AVPR1B ADCY2 ADCY2 NPPC NPPC CALM1 CALM1 ADCY4 ADCY4 PLA2G1B PLA2G1B ADORA2A ADORA2A PRKCA PRKCA GNA13 GNA13 PLCB1 PLCB1 ITPR1 ITPR1 F6Y3Q3_MONDO F6Y3Q3_MONDO PLA2G10 PLA2G10 LOC100026693 LOC100026693 AVP AVP PLA2G12A PLA2G12A RAF1 RAF1 NPR2 NPR2 LOC100017854 LOC100017854 ADRA1B ADRA1B ADM ADM MYH10 MYH10 PRKCH PRKCH RAMP1 RAMP1 AGT AGT PTGIR PTGIR CALML4 CALML4 PLA2G3 PLA2G3 MAP2K1 MAP2K1 ACTG2 ACTG2 EDN1 EDN1 PRKCD PRKCD CALCRL CALCRL F7FK82_MONDO F7FK82_MONDO NPPA NPPA MYLK3 MYLK3 GNAQ GNAQ ADCY7 ADCY7 ARHGEF12 ARHGEF12 PLA2G4C PLA2G4C AVPR1A AVPR1A RAMP2 RAMP2 ADRA1D ADRA1D PPP1CB PPP1CB MAPK3 MAPK3 ADCY3 ADCY3 LOC103106467 LOC103106467 PLA2G2E PLA2G2E ADCY9 ADCY9 PRKG1 PRKG1 ITPR2 ITPR2 PRKCQ PRKCQ ADRA1A ADRA1A ARHGEF11 ARHGEF11 NPR1 NPR1 MAPK1 MAPK1 PLA2G4E PLA2G4E MYLK MYLK GNA11 GNA11 KCNMB4 KCNMB4 PPP1R12A PPP1R12A KCNMB3 KCNMB3 KCNMB2 KCNMB2 F7D7P9_MONDO F7D7P9_MONDO BRAF BRAF CALML3 CALML3 AGTR1 AGTR1 CACNA1S CACNA1S ACTA2 ACTA2 F6UHQ4_MONDO F6UHQ4_MONDO PLA2G2D PLA2G2D EDN2 EDN2 KCNMA1 KCNMA1 MYL9 MYL9 LOC103105270 LOC103105270 PRKCB PRKCB ADCY1 ADCY1 PPP1CC PPP1CC MYLK4 MYLK4 PLA2G6 PLA2G6 PLCB4 PLCB4 PRKACA PRKACA KCNMB1 KCNMB1 CALD1 CALD1 ARAF ARAF GUCY1B1 GUCY1B1 CACNA1C CACNA1C MYH11 MYH11 KCNU1 KCNU1 PLA2G2C PLA2G2C ITPR3 ITPR3 RAMP3 RAMP3 ROCK1 ROCK1 SIRT6 SIRT6 PROCA1 PROCA1 RHOA RHOA EDN3 EDN3 F7GAG3_MONDO F7GAG3_MONDO ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G12BPhospholipase A2 group XIIB. (194 aa)
GNA12G protein subunit alpha 12. (380 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PRKCEProtein kinase domain-containing protein. (212 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
LOC100023663Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
NPPCNatriuretic peptide C. (128 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
PLA2G1BPhospholipase A(2). (164 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
GNA13G protein subunit alpha 13. (377 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
F6Y3Q3_MONDOGuanylate cyclase. (847 aa)
PLA2G10Phospholipase A(2). (147 aa)
LOC100026693Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (168 aa)
AVPUncharacterized protein; Belongs to the vasopressin/oxytocin family. (170 aa)
PLA2G12APhospholipase A2 group XIIA. (194 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
NPR2Guanylate cyclase. (1047 aa)
LOC100017854Uncharacterized protein; Belongs to the actin family. (412 aa)
ADRA1BAdrenoceptor alpha 1B. (505 aa)
ADMUncharacterized protein. (83 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2047 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
RAMP1Uncharacterized protein. (177 aa)
AGTAngiotensinogen; Belongs to the serpin family. (469 aa)
PTGIRProstaglandin I2 receptor. (364 aa)
CALML4Calmodulin like 4. (156 aa)
PLA2G3Uncharacterized protein. (688 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ACTG2Uncharacterized protein. (376 aa)
EDN1Endothelin 1. (214 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (489 aa)
F7FK82_MONDOGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (667 aa)
NPPANatriuretic peptide A. (160 aa)
MYLK3Myosin light chain kinase 3. (846 aa)
GNAQG protein subunit alpha q. (359 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1539 aa)
PLA2G4CPLA2c domain-containing protein. (204 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
RAMP2Uncharacterized protein. (102 aa)
ADRA1DAdrenoceptor alpha 1D. (555 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
LOC103106467Phospholipase A(2). (144 aa)
PLA2G2EPhospholipase A(2). (143 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (455 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
ADRA1AAdrenoceptor alpha 1A. (465 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1552 aa)
NPR1Guanylate cyclase. (904 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PLA2G4EPhospholipase A2. (868 aa)
MYLKMyosin light chain kinase. (1948 aa)
GNA11G protein subunit alpha 11. (359 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (878 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (284 aa)
KCNMB2Uncharacterized protein. (228 aa)
F7D7P9_MONDOUncharacterized protein; Belongs to the calmodulin family. (65 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
ACTA2Uncharacterized protein; Belongs to the actin family. (237 aa)
F6UHQ4_MONDOPhospholipase A(2). (144 aa)
PLA2G2DPhospholipase A(2). (145 aa)
EDN2Uncharacterized protein. (178 aa)
KCNMA1BK_channel_a domain-containing protein. (189 aa)
MYL9Uncharacterized protein. (172 aa)
LOC103105270Phospholipase A(2). (146 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
MYLK4Protein kinase domain-containing protein. (690 aa)
PLA2G6Phospholipase A2 group VI. (818 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
KCNMB1Uncharacterized protein. (203 aa)
CALD1Caldesmon 1. (784 aa)
ARAFUncharacterized protein. (198 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (626 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1201 aa)
PLA2G2CPhospholipase A(2). (147 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
RAMP3Receptor activity modifying protein 3. (159 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
SIRT6Uncharacterized protein. (547 aa)
PROCA1PA2c domain-containing protein. (380 aa)
RHOAUncharacterized protein. (193 aa)
EDN3Uncharacterized protein. (219 aa)
F7GAG3_MONDOPLA2c domain-containing protein. (590 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.