STRINGSTRING
SRC SRC PAK6 PAK6 TRPC6 TRPC6 PLCG1 PLCG1 RAC2 RAC2 EPHB6 EPHB6 EPHA1 EPHA1 GNAI3 GNAI3 SRGAP2 SRGAP2 PIK3R3 PIK3R3 NCK2 NCK2 PTCH1 PTCH1 NTNG1 NTNG1 SEMA6D SEMA6D NFATC4 NFATC4 PTPN11 PTPN11 RAC3 RAC3 PRKCA PRKCA SEMA4F SEMA4F PAK5 PAK5 EPHB4 EPHB4 SHH SHH F7AT60_MONDO F7AT60_MONDO PAK1 PAK1 CFL2 CFL2 PARD6A PARD6A ABLIM3 ABLIM3 MYL5 MYL5 RAF1 RAF1 LOC100026375 LOC100026375 NRP1 NRP1 RHOD RHOD NTN4 NTN4 FZD3 FZD3 PDK1 PDK1 PLXNC1 PLXNC1 PPP3CC PPP3CC LIMK2 LIMK2 SSH2 SSH2 CXCL12 CXCL12 TRPC4 TRPC4 EFNB1 EFNB1 UNC5D UNC5D DCC DCC SEMA3G SEMA3G SEMA4G SEMA4G SEMA3B SEMA3B SEMA3F SEMA3F NTNG2 NTNG2 ARHGEF12 ARHGEF12 LIMK1 LIMK1 PLXNB1 PLXNB1 SMO SMO LRRC4 LRRC4 PLCG2 PLCG2 NTN3 NTN3 MAPK3 MAPK3 MET MET EPHA8 EPHA8 EPHB2 EPHB2 CAMK2B CAMK2B BMPR2 BMPR2 PARD6B PARD6B BMP7 BMP7 SEMA4A SEMA4A EPHA3 EPHA3 SEMA3E SEMA3E EPHA6 EPHA6 SEMA3C SEMA3C EFNA4 EFNA4 GNAI1 GNAI1 MAPK1 MAPK1 EPHA7 EPHA7 WNT5A WNT5A PAK2 PAK2 RYK RYK EPHB1 EPHB1 NCK1 NCK1 SEMA6C SEMA6C TRPC3 TRPC3 F7FNN8_MONDO F7FNN8_MONDO UNC5C UNC5C BMPR1B BMPR1B FES FES SEMA4B SEMA4B PIK3R1 PIK3R1 PPP3CA PPP3CA EPHA5 EPHA5 EPHA4 EPHA4 PIK3CA PIK3CA LOC100617582 LOC100617582 L1CAM L1CAM SEMA4C SEMA4C RGS3 RGS3 CDC42 CDC42 F7CI75_MONDO F7CI75_MONDO EFNA3 EFNA3 LRRC4C LRRC4C SEMA3A SEMA3A RGMA RGMA ENAH ENAH PLXNA2 PLXNA2 F6TU13_MONDO F6TU13_MONDO SEMA5B SEMA5B KRAS-2 KRAS-2 ROBO2-2 ROBO2-2 K7E1M2_MONDO K7E1M2_MONDO ITGB1 ITGB1 DPYSL2 DPYSL2 EFNA5 EFNA5 GNAI2 GNAI2 EFNA2 EFNA2 PRKCZ PRKCZ NFATC3 NFATC3 MYL9 MYL9 ROBO1 ROBO1 ABL1 ABL1 PPP3CB PPP3CB CXCR4 CXCR4 RASA1 RASA1 SLIT2 SLIT2 NGEF NGEF SEMA6A SEMA6A RRAS RRAS ILK ILK SLIT3 SLIT3 GDF7 GDF7 NRAS NRAS EFNA1 EFNA1 SEMA4D SEMA4D TRPC1 TRPC1 SEMA5A SEMA5A NFATC2 NFATC2 UNC5A UNC5A PLXNB2 PLXNB2 PARD3 PARD3 ABLIM2 ABLIM2 PLXNA3 PLXNA3 PTK2 PTK2 PIK3CB PIK3CB WNT5B WNT5B PLXNB3 PLXNB3 SRGAP3 SRGAP3 PARD6G PARD6G ROCK1 ROCK1 MYL12A MYL12A ROBO3 ROBO3 PAK4 PAK4 WNT4 WNT4 RHOA RHOA CDK5 CDK5 DPYSL5 DPYSL5 EFNB2 EFNB2 CAMK2D CAMK2D LOC103099055 LOC103099055 SEMA3D SEMA3D GSK3B GSK3B EFNB3 EFNB3 HRAS HRAS EPHB3 EPHB3 ROCK2 ROCK2 NEO1 NEO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (550 aa)
PAK6P21 (RAC1) activated kinase 6. (592 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (903 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
RAC2Rac family small GTPase 2. (281 aa)
EPHB6EPH receptor B6. (1006 aa)
EPHA1EPH receptor A1. (980 aa)
GNAI3G protein subunit alpha i3. (399 aa)
SRGAP2Uncharacterized protein. (1073 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
NCK2Cytoplasmic protein. (380 aa)
PTCH1Patched 1. (1521 aa)
NTNG1Netrin G1. (451 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1066 aa)
NFATC4Nuclear factor of activated T cells 4. (902 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa)
RAC3Rac family small GTPase 3. (192 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (795 aa)
PAK5Non-specific serine/threonine protein kinase. (812 aa)
EPHB4EPH receptor B4. (918 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (480 aa)
F7AT60_MONDOUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (466 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CFL2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (195 aa)
PARD6APar-6 family cell polarity regulator alpha. (518 aa)
ABLIM3HP domain-containing protein. (293 aa)
MYL5Myosin light chain 5. (170 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
LOC100026375Uncharacterized protein. (636 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (922 aa)
RHODUncharacterized protein. (235 aa)
NTN4Netrin 4. (589 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PDK1Protein-serine/threonine kinase. (427 aa)
PLXNC1Plexin C1. (1582 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
LIMK2LIM domain kinase 2. (684 aa)
SSH2Slingshot protein phosphatase 2. (1424 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (975 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (343 aa)
UNC5DUnc-5 netrin receptor D. (828 aa)
DCCDCC netrin 1 receptor. (1403 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (760 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (840 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (764 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (726 aa)
NTNG2Netrin G2. (588 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1539 aa)
LIMK1LIM domain kinase 1. (602 aa)
PLXNB1Plexin B1. (2191 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa)
LRRC4Leucine rich repeat containing 4. (650 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
NTN3Netrin 3. (583 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1387 aa)
EPHA8EPH receptor A8. (1003 aa)
EPHB2EPH receptor B2. (962 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (671 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
PARD6BUncharacterized protein. (370 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (790 aa)
EPHA3EPH receptor A3. (984 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (715 aa)
EPHA6Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (454 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (753 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (217 aa)
GNAI1G protein subunit alpha i1. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
EPHA7EPH receptor A7. (998 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa)
PAK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
RYKReceptor like tyrosine kinase. (630 aa)
EPHB1EPH receptor B1. (545 aa)
NCK1Cytoplasmic protein. (419 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (973 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (925 aa)
F7FNN8_MONDOUncharacterized protein. (199 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (818 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
EPHA5EPH receptor A5. (1050 aa)
EPHA4EPH receptor A4. (986 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100617582Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
L1CAML1 cell adhesion molecule. (1230 aa)
SEMA4CUncharacterized protein; Belongs to the semaphorin family. (832 aa)
RGS3Regulator of G protein signaling 3. (876 aa)
CDC42Cell division cycle 42. (191 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (450 aa)
ENAHENAH actin regulator. (825 aa)
PLXNA2Plexin A2. (1875 aa)
F6TU13_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
SEMA5BSemaphorin 5B. (1092 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
ROBO2-2Ig-like domain-containing protein. (121 aa)
K7E1M2_MONDOUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
DPYSL2Dihydropyrimidinase like 2. (678 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
GNAI2G protein subunit alpha i2. (315 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (200 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
MYL9Uncharacterized protein. (172 aa)
ROBO1Roundabout guidance receptor 1. (1732 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
CXCR4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa)
RASA1RAS p21 protein activator 1. (1022 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
NGEFUncharacterized protein. (981 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1045 aa)
RRASRAS related. (255 aa)
ILKIntegrin linked kinase. (486 aa)
SLIT3Slit guidance ligand 3. (1532 aa)
GDF7TGF_BETA_2 domain-containing protein. (461 aa)
NRASGTPase NRas. (195 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (267 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (737 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (749 aa)
SEMA5ASemaphorin 5A. (1083 aa)
NFATC2Nuclear factor of activated T cells 2. (927 aa)
UNC5AUnc-5 netrin receptor A. (864 aa)
PLXNB2Sema domain-containing protein. (602 aa)
PARD3Par-3 family cell polarity regulator. (1358 aa)
ABLIM2Actin binding LIM protein family member 2. (645 aa)
PLXNA3Plexin A3. (1859 aa)
PTK2Uncharacterized protein. (161 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (447 aa)
PLXNB3Plexin B3. (1937 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1083 aa)
PARD6GPar-6 family cell polarity regulator gamma. (383 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
MYL12AMyosin light chain 12A. (178 aa)
ROBO3Uncharacterized protein. (419 aa)
PAK4Non-specific serine/threonine protein kinase. (616 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
RHOAUncharacterized protein. (193 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
DPYSL5Dihydropyrimidinase like 5. (614 aa)
EFNB2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (333 aa)
CAMK2DProtein kinase domain-containing protein. (145 aa)
LOC103099055Uncharacterized protein; Belongs to the semaphorin family. (776 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (778 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (339 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
EPHB3Uncharacterized protein. (538 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
NEO1Neogenin 1. (1576 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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