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| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (795 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | PRKCE | Protein kinase domain-containing protein. (212 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa) |
| | GNB5 | G protein subunit beta 5. (353 aa) |
| | GNAI3 | G protein subunit alpha i3. (399 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | ADCY10 | Adenylate cyclase 10. (1590 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (888 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (551 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | MEF2B | Myocyte enhancer factor 2B. (398 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (580 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (666 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (523 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | PDE3B | Phosphodiesterase. (1156 aa) |
| | LOC100017854 | Uncharacterized protein; Belongs to the actin family. (412 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (476 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (873 aa) |
| | SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (627 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | CALML4 | Calmodulin like 4. (156 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | MYL2 | Myosin light chain 2. (166 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1410 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa) |
| | MYLK3 | Myosin light chain kinase 3. (846 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa) |
| | APLN | Uncharacterized protein. (204 aa) |
| | LIPE | HSL_N domain-containing protein. (664 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | MYL3 | Myosin light chain 3. (197 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (392 aa) |
| | NOTCH3 | Notch receptor 3. (1847 aa) |
| | NRF1 | Nuclear respiratory factor 1. (503 aa) |
| | BECN1 | Uncharacterized protein. (448 aa) |
| | PRKAB1 | AMPKBI domain-containing protein. (273 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (471 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (310 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | TFAM | Uncharacterized protein. (259 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1099 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | CCN2 | Cellular communication network factor 2. (351 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | MYLK | Myosin light chain kinase. (1948 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | F7FNN8_MONDO | Uncharacterized protein. (199 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa) |
| | F7D7P9_MONDO | Uncharacterized protein; Belongs to the calmodulin family. (65 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) |
| | NOS1 | Nitric oxide synthase 1. (1464 aa) |
| | SLC8A2 | Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (431 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1103 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa) |
| | PLIN1 | Perilipin 1. (544 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | F6VUA1_MONDO | Uncharacterized protein. (139 aa) |
| | KRAS-2 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa) |
| | ACTA2 | Uncharacterized protein; Belongs to the actin family. (237 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | GNAI2 | G protein subunit alpha i2. (315 aa) |
| | KLF2 | Uncharacterized protein. (77 aa) |
| | SPHK1 | Sphingosine kinase 1. (454 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | RYR2 | Ryanodine receptor 2. (4900 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (413 aa) |
| | MYLK4 | Protein kinase domain-containing protein. (690 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | RRAS | RAS related. (255 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (426 aa) |
| | NRAS | GTPase NRas. (195 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | RRAS2 | Uncharacterized protein. (200 aa) |
| | CCND1 | Uncharacterized protein. (67 aa) |
| | RYR3 | Ryanodine receptor 3. (4841 aa) |
| | PRKAB2 | AMPKBI domain-containing protein. (106 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | SPP1 | Uncharacterized protein. (302 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa) |
| | GABARAPL2 | Uncharacterized protein. (289 aa) |
| | LOC100010184 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | SIRT6 | Uncharacterized protein. (547 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (1040 aa) |
| | GNB2 | G protein subunit beta 2. (367 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa) |
| | HRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
