STRINGSTRING
AMOTL1 AMOTL1 SRC SRC TJP3 TJP3 ACTR3 ACTR3 LOC100015203 LOC100015203 PRKCE PRKCE MYH9 MYH9 RAP1A RAP1A CLDN2 CLDN2 MARVELD3 MARVELD3 PATJ PATJ TJP2 TJP2 EPB41L4B EPB41L4B JUN JUN ACTR2 ACTR2 PRKAA2 PRKAA2 DLG2 DLG2 PRKAG2 PRKAG2 ACTR3B ACTR3B PARD6A PARD6A AFDN AFDN CLDN7 CLDN7 F7G4H7_MONDO F7G4H7_MONDO SLC9A3R1 SLC9A3R1 LLGL2 LLGL2 NEDD4 NEDD4 MYH10 MYH10 CGNL1 CGNL1 MICALL2 MICALL2 SYNPO SYNPO MPP5 MPP5 PPP2R2B PPP2R2B WAS WAS RAB8B RAB8B MYL2 MYL2 PCNA PCNA TJP1 TJP1 GATA4 GATA4 LOC100028958 LOC100028958 HSPA4 HSPA4 PPP2CA PPP2CA CLDN25 CLDN25 PPP2R1B PPP2R1B RDX RDX RAB8A RAB8A MAP2K7 MAP2K7 CLDN16 CLDN16 LOC100010481 LOC100010481 PRKAB1 PRKAB1 RAP2C RAP2C PRKAG3 PRKAG3 PRKAG1 PRKAG1 CFTR CFTR CLDN11 CLDN11 PRKCI PRKCI PARD6B PARD6B CLDN9 CLDN9 PPP2R2A PPP2R2A CLDN19 CLDN19 MAP3K5 MAP3K5 BVES BVES YBX3 YBX3 TUBA8 TUBA8 AMOTL2 AMOTL2 CLDN18 CLDN18 PPP2CB PPP2CB WHAMM WHAMM OCLN OCLN MARVELD2 MARVELD2 MAP3K1 MAP3K1 PPP2R2D PPP2R2D PRKAA1 PRKAA1 MAPK10 MAPK10 PPP2R1A PPP2R1A RUNX1 RUNX1 LOC100617582 LOC100617582 MPDZ MPDZ LOC100016601 LOC100016601 CLDN20 CLDN20 MAPK9 MAPK9 CDC42 CDC42 F7CI75_MONDO F7CI75_MONDO CLDN6 CLDN6 LOC100020439 LOC100020439 F6TU13_MONDO F6TU13_MONDO LOC100016275 LOC100016275 LOC100016236 LOC100016236 HCLS1 HCLS1 CLDN34 CLDN34 MSN MSN CLDN17 CLDN17 LLGL1 LLGL1 CLDN14 CLDN14 K7E1M2_MONDO K7E1M2_MONDO LOC103103995 LOC103103995 STK11 STK11 ITGB1 ITGB1 PRKCZ PRKCZ MYL9 MYL9 JAM2 JAM2 LOC103097444 LOC103097444 ACTG1 ACTG1 CLDN1 CLDN1 MAGI1 MAGI1 FIS1 FIS1 ARHGEF2 ARHGEF2 ARHGAP17 ARHGAP17 EZR EZR TJAP1 TJAP1 PRKACA PRKACA CCND1 CCND1 TUBA1B TUBA1B TIAM1 TIAM1 ERBB2 ERBB2 CGN CGN MYH11 MYH11 PARD3 PARD3 PRKAB2 PRKAB2 DLG1 DLG1 CLDN10 CLDN10 CLDN5 CLDN5 ACTN4 ACTN4 NF2 NF2 F11R F11R PARD6G PARD6G RAPGEF2 RAPGEF2 RAB13 RAB13 ROCK1 ROCK1 NEDD4L NEDD4L MYL12A MYL12A RHOA RHOA SYMPK SYMPK RAPGEF6 RAPGEF6 JAM3 JAM3 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMOTL1Angiomotin like 1. (961 aa)
SRCTyrosine-protein kinase. (550 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (917 aa)
ACTR3Uncharacterized protein; Belongs to the actin family. (569 aa)
LOC100015203Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PRKCEProtein kinase domain-containing protein. (212 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
RAP1AUncharacterized protein. (177 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
MARVELD3MARVEL domain containing 3. (477 aa)
PATJUncharacterized protein. (680 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1198 aa)
EPB41L4BFERM domain-containing protein. (893 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
PRKAA2Non-specific serine/threonine protein kinase. (551 aa)
DLG2Uncharacterized protein. (392 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (580 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (418 aa)
PARD6APar-6 family cell polarity regulator alpha. (518 aa)
AFDNAfadin, adherens junction formation factor. (1864 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
F7G4H7_MONDOFERM domain-containing protein. (482 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1046 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1238 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2047 aa)
CGNL1Cingulin like 1. (1316 aa)
MICALL2Uncharacterized protein. (899 aa)
SYNPOSynaptopodin. (940 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (484 aa)
WASWASP actin nucleation promoting factor. (504 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
MYL2Myosin light chain 2. (166 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1738 aa)
GATA4GATA binding protein 4. (451 aa)
LOC100028958Uncharacterized protein. (375 aa)
HSPA4Heat shock protein family A (Hsp70) member 4. (840 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CLDN25Claudin 25. (229 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (627 aa)
RDXRadixin. (598 aa)
RAB8ARAB8A, member RAS oncogene family. (280 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
LOC100010481Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
PRKAB1AMPKBI domain-containing protein. (273 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (471 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (310 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (579 aa)
PARD6BUncharacterized protein. (370 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (419 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1390 aa)
BVESBlood vessel epicardial substance. (355 aa)
YBX3Y-box binding protein 3. (309 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
AMOTL2Angiomotin like 2. (767 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (253 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (803 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (523 aa)
MARVELD2MARVEL domain containing 2. (543 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1491 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (417 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (410 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (461 aa)
LOC100617582Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
MPDZUncharacterized protein. (964 aa)
LOC100016601Uncharacterized protein. (374 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CDC42Cell division cycle 42. (191 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (378 aa)
LOC100020439Uncharacterized protein; Belongs to the actin family. (374 aa)
F6TU13_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
LOC100016275Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC100016236Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
HCLS1SH3 domain-containing protein. (408 aa)
CLDN34Uncharacterized protein. (199 aa)
MSNMoesin. (574 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1053 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
K7E1M2_MONDOUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
LOC103103995Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
MYL9Uncharacterized protein. (172 aa)
JAM2Uncharacterized protein. (697 aa)
LOC103097444MARVEL domain-containing protein. (296 aa)
ACTG1Uncharacterized protein. (375 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1113 aa)
FIS1Uncharacterized protein. (274 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1219 aa)
ARHGAP17Rho GTPase activating protein 17. (875 aa)
EZREzrin. (587 aa)
TJAP1Uncharacterized protein. (547 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
CCND1Uncharacterized protein. (67 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1575 aa)
ERBB2Receptor protein-tyrosine kinase. (1257 aa)
CGNMyosin_tail_1 domain-containing protein. (2108 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
PARD3Par-3 family cell polarity regulator. (1358 aa)
PRKAB2AMPKBI domain-containing protein. (106 aa)
DLG1Uncharacterized protein; Belongs to the MAGUK family. (855 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (256 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ACTN4Actinin alpha 4. (934 aa)
NF2Neurofibromin 2. (595 aa)
F11RUncharacterized protein. (342 aa)
PARD6GPar-6 family cell polarity regulator gamma. (383 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1703 aa)
RAB13Uncharacterized protein. (140 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1272 aa)
MYL12AMyosin light chain 12A. (178 aa)
RHOAUncharacterized protein. (193 aa)
SYMPKSymplekin. (1313 aa)
RAPGEF6Uncharacterized protein. (1659 aa)
JAM3Junctional adhesion molecule 3. (340 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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