STRINGSTRING
LBP LBP TICAM1 TICAM1 IL6 IL6 IKBKE IKBKE PIK3R3 PIK3R3 JUN JUN IFN3 IFN3 LOC100021419 LOC100021419 TIRAP TIRAP TLR3 TLR3 FOS FOS MAP2K6 MAP2K6 AKT3 AKT3 AKT2 AKT2 MAP3K8 MAP3K8 RIPK1 RIPK1 IKBKG IKBKG TAB1 TAB1 RELA RELA MAP2K1 MAP2K1 IKBKB IKBKB CHUK CHUK IL12A IL12A STAT1 STAT1 TRAF3 TRAF3 IRF3 IRF3 TICAM2 TICAM2 MAPK13 MAPK13 AKT1 AKT1 IL1B IL1B MAP2K7 MAP2K7 CASP8 CASP8 MAPK3 MAPK3 TLR8 TLR8 MAPK1 MAPK1 CD80 CD80 IRAK4 IRAK4 LOC103099606 LOC103099606 LOC100020842 LOC100020842 CCL5 CCL5 CXCL8 CXCL8 TLR4 TLR4 PIK3R1 PIK3R1 TRAF6 TRAF6 TLR6 TLR6 NFKB1 NFKB1 MAPK10 MAPK10 PIK3CA PIK3CA MAPK9 MAPK9 CD14 CD14 TLR5 TLR5 TLR2 TLR2 CD86 CD86 LOC100021467 LOC100021467 LOC100021258 LOC100021258 LY96 LY96 LOC100017283 LOC100017283 LOC100017328 LOC100017328 CXCL9 CXCL9 CASP18 CASP18 MAP2K3 MAP2K3 IFNAR2 IFNAR2 MAP3K7 MAP3K7 MAPK14 MAPK14 IFN7 IFN7 TLR9 TLR9 SPP1 SPP1 PIK3CB PIK3CB CTSK CTSK MAPK12 MAPK12 TAB2 TAB2 NFKBIA NFKBIA IFN4 IFN4 LOC100021368 LOC100021368 SIRT6 SIRT6 CXCL11 CXCL11 IFN2 IFN2 TOLLIP TOLLIP FADD FADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LBPLipopolysaccharide binding protein. (483 aa)
TICAM1TRIF-NTD domain-containing protein. (713 aa)
IL6Uncharacterized protein. (220 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
IFN3Uncharacterized protein. (184 aa)
LOC100021419Type I interferon 5. (184 aa)
TIRAPTIR domain-containing protein. (342 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (706 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (652 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (409 aa)
TICAM2TIR domain-containing protein. (223 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (472 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1048 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
CD80Uncharacterized protein. (337 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
LOC103099606C-C motif chemokine. (95 aa)
LOC100020842C-C motif chemokine. (156 aa)
CCL5C-C motif chemokine ligand 5. (91 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
TLR6Toll like receptor 6; Belongs to the Toll-like receptor family. (803 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CD14Uncharacterized protein. (382 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (861 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
CD86Uncharacterized protein. (238 aa)
LOC100021467Uncharacterized protein. (183 aa)
LOC100021258Type I interferon 1. (198 aa)
LY96ML domain-containing protein. (157 aa)
LOC100017283C-C motif chemokine. (91 aa)
LOC100017328C-C motif chemokine. (95 aa)
CXCL9C-X-C motif chemokine. (123 aa)
CASP18Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
MAP2K3Mitogen-activated protein kinase kinase 3. (239 aa)
IFNAR2Uncharacterized protein. (511 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IFN7Type I interferon 7. (183 aa)
TLR9TIR domain-containing protein. (1063 aa)
SPP1Uncharacterized protein. (302 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (332 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
IFN4Type I interferon 4. (183 aa)
LOC100021368Uncharacterized protein. (183 aa)
SIRT6Uncharacterized protein. (547 aa)
CXCL11C-X-C motif chemokine ligand 11. (87 aa)
IFN2Type I interferon 2. (183 aa)
TOLLIPCUE domain-containing protein. (274 aa)
FADDUncharacterized protein. (193 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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