STRINGSTRING
RBPJ RBPJ PLCG1 PLCG1 IL2RB IL2RB JAK1 JAK1 CD247 CD247 JUN JUN ZAP70 ZAP70 IL2RG IL2RG TYK2 TYK2 FOS FOS IKBKG IKBKG PPP3CC PPP3CC RELA RELA IKBKB IKBKB CHUK CHUK IL12A IL12A STAT1 STAT1 STAT4 STAT4 TBX21 TBX21 NFKBIB NFKBIB CD3G CD3G CD3D CD3D MAPK13 MAPK13 IL5 IL5 LOC100026858 LOC100026858 NOTCH3 NOTCH3 LOC100026112 LOC100026112 JAG2 JAG2 LOC100026007 LOC100026007 LOC100011470 LOC100011470 LOC100012174 LOC100012174 JAK2 JAK2 MAPK3 MAPK3 RBPJL RBPJL PRKCQ PRKCQ GATA3 GATA3 LCK LCK MAPK1 MAPK1 NFKBIE NFKBIE NFKB1 NFKB1 PPP3CA PPP3CA MAPK10 MAPK10 IFNGR2 IFNGR2 STAT6 STAT6 MAF MAF JAG1 JAG1 NOTCH2 NOTCH2 MAML1 MAML1 MAPK9 MAPK9 CD4 CD4 LOC100025909 LOC100025909 IL4R IL4R DLL4 DLL4 NFATC3 NFATC3 LOC100025932 LOC100025932 ENSMODP00000045162 ENSMODP00000045162 RUNX3 RUNX3 PPP3CB PPP3CB HLA-DRA HLA-DRA CD3E CD3E NFATC1 NFATC1 MAPK14 MAPK14 ENSMODP00000047908 ENSMODP00000047908 DLL1 DLL1 NFATC2 NFATC2 IL2 IL2 MAML3 MAML3 MAPK12 MAPK12 NFKBIA NFKBIA F7BIP4_MONDO F7BIP4_MONDO MAML2 MAML2 IFNGR1 IFNGR1 LOC100026891 LOC100026891
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (497 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
IL2RBFibronectin type-III domain-containing protein. (562 aa)
JAK1Protein kinase domain-containing protein. (199 aa)
CD247CD247 molecule. (166 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
IL2RGFibronectin type-III domain-containing protein. (301 aa)
TYK2Tyrosine-protein kinase. (1193 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
STAT4Signal transducer and activator of transcription. (749 aa)
TBX21T-box_assoc domain-containing protein. (575 aa)
NFKBIBNFKB inhibitor beta. (314 aa)
CD3GCD3g molecule. (180 aa)
CD3DIg_4 domain-containing protein. (272 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (137 aa)
LOC100026858Ig-like domain-containing protein. (262 aa)
NOTCH3Notch receptor 3. (1847 aa)
LOC100026112Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1247 aa)
LOC100026007Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
LOC100011470Signal transducer and activator of transcription. (839 aa)
LOC100012174Signal transducer and activator of transcription. (782 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (513 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
GATA3GATA binding protein 3. (444 aa)
LCKTyrosine-protein kinase. (686 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
NFKBIENFKB inhibitor epsilon. (360 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
IFNGR2Uncharacterized protein. (344 aa)
STAT6Signal transducer and activator of transcription. (839 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (395 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
NOTCH2Notch receptor 2. (2476 aa)
MAML1Mastermind like transcriptional coactivator 1. (1032 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CD4CD4. (461 aa)
LOC100025909Ig-like domain-containing protein. (282 aa)
IL4RIL4Ra_N domain-containing protein. (930 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
LOC100025932Ig-like domain-containing protein; Belongs to the MHC class II family. (264 aa)
ENSMODP00000045162Ig-like domain-containing protein; Belongs to the MHC class II family. (276 aa)
RUNX3Runt domain-containing protein. (115 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (287 aa)
CD3EIGc2 domain-containing protein. (252 aa)
NFATC1Nuclear factor of activated T cells 1. (950 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSMODP00000047908Ig-like domain-containing protein; Belongs to the MHC class II family. (267 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (734 aa)
NFATC2Nuclear factor of activated T cells 2. (927 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
MAML3Uncharacterized protein. (360 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
F7BIP4_MONDOIg-like domain-containing protein. (182 aa)
MAML2Mastermind like transcriptional coactivator 2. (1129 aa)
IFNGR1Fibronectin type-III domain-containing protein. (503 aa)
LOC100026891Ig-like domain-containing protein. (270 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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