STRINGSTRING
RAC2 RAC2 PIK3R3 PIK3R3 RAC3 RAC3 JUN JUN PIK3AP1 PIK3AP1 BLNK BLNK FOS FOS RAF1 RAF1 AKT3 AKT3 GRB2 GRB2 AKT2 AKT2 INPPL1 INPPL1 SOS1 SOS1 IKBKG IKBKG PPP3CC PPP3CC RELA RELA MAP2K1 MAP2K1 IKBKB IKBKB CHUK CHUK BTK BTK SOS2 SOS2 NFKBIB NFKBIB AKT1 AKT1 CD22 CD22 PLCG2 PLCG2 RASGRP3 RASGRP3 MAPK3 MAPK3 MAPK1 MAPK1 PTPN6 PTPN6 NFKBIE NFKBIE F7FNN8_MONDO F7FNN8_MONDO PIK3R1 PIK3R1 NFKB1 NFKB1 PPP3CA PPP3CA PIK3CA PIK3CA VAV1 VAV1 KRAS-2 KRAS-2 K7DYV5_MONDO K7DYV5_MONDO NFATC3 NFATC3 PPP3CB PPP3CB PRKCB PRKCB INPP5D INPP5D NFATC1 NFATC1 CD72 CD72 NRAS NRAS LOC100015202 LOC100015202 NFATC2 NFATC2 BCL10 BCL10 PIK3CB PIK3CB VAV3 VAV3 CARD11 CARD11 NFKBIA NFKBIA SYK SYK SIRT6 SIRT6 LYN LYN GSK3B GSK3B DAPP1 DAPP1 HRAS HRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAC2Rac family small GTPase 2. (281 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
RAC3Rac family small GTPase 3. (192 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (806 aa)
BLNKB cell linker. (466 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1013 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
BTKTyrosine-protein kinase. (655 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1328 aa)
NFKBIBNFKB inhibitor beta. (314 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CD22Uncharacterized protein. (793 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
RASGRP3RAS guanyl releasing protein 3. (647 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
NFKBIENFKB inhibitor epsilon. (360 aa)
F7FNN8_MONDOUncharacterized protein. (199 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
K7DYV5_MONDOIg-like domain-containing protein. (295 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1183 aa)
NFATC1Nuclear factor of activated T cells 1. (950 aa)
CD72Uncharacterized protein. (284 aa)
NRASGTPase NRas. (195 aa)
LOC100015202Ig-like domain-containing protein. (321 aa)
NFATC2Nuclear factor of activated T cells 2. (927 aa)
BCL10CARD domain-containing protein. (245 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
CARD11Caspase recruitment domain family member 11. (1176 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
SYKTyrosine-protein kinase. (588 aa)
SIRT6Uncharacterized protein. (547 aa)
LYNTyrosine-protein kinase. (516 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (282 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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