STRINGSTRING
PLCG1 PLCG1 RAC2 RAC2 LOC100015157 LOC100015157 PRKCE PRKCE ARPC1A ARPC1A ARPC1B ARPC1B ASAP2 ASAP2 F6V079_MONDO F6V079_MONDO PIK3R3 PIK3R3 PIP5K1B PIP5K1B MYO10 MYO10 PLPP3 PLPP3 PRKCA PRKCA GAB2 GAB2 PAK1 PAK1 ARPC4 ARPC4 CFL2 CFL2 RAF1 RAF1 PLPP2 PLPP2 AKT3 AKT3 RPS6KB1 RPS6KB1 F6PU44_MONDO F6PU44_MONDO NCF1 NCF1 ARPC5 ARPC5 RPS6KB2 RPS6KB2 AKT2 AKT2 INPPL1 INPPL1 LIMK2 LIMK2 MAP2K1 MAP2K1 WAS WAS PRKCD PRKCD F6U132_MONDO F6U132_MONDO PLA2G4C PLA2G4C AKT1 AKT1 LIMK1 LIMK1 PLCG2 PLCG2 ARPC2 ARPC2 MAPK3 MAPK3 CRKL CRKL MAPK1 MAPK1 PLA2G4E PLA2G4E PIP5K1A PIP5K1A HCK HCK GSN GSN PIK3R1 PIK3R1 ARPC5L ARPC5L LOC100015800 LOC100015800 PIK3CA PIK3CA PLD2 PLD2 SCIN SCIN ARF6 ARF6 WASF2 WASF2 CDC42 CDC42 VAV1 VAV1 F7CI75_MONDO F7CI75_MONDO K7DYV5_MONDO K7DYV5_MONDO MARCKS MARCKS ASAP1 ASAP1 SPHK1 SPHK1 PLPP1 PLPP1 PRKCB PRKCB INPP5D INPP5D PLA2G6 PLA2G6 LOC100015202 LOC100015202 DNM2 DNM2 PLD1 PLD1 PIK3CB PIK3CB WASF3 WASF3 VAV3 VAV3 MARCKSL1 MARCKSL1 SYK SYK LYN LYN BIN1 BIN1 F7GAG3_MONDO F7GAG3_MONDO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
RAC2Rac family small GTPase 2. (281 aa)
LOC100015157Uncharacterized protein. (238 aa)
PRKCEProtein kinase domain-containing protein. (212 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (367 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1013 aa)
F6V079_MONDOacidPPc domain-containing protein. (161 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (556 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1309 aa)
PLPP3acidPPc domain-containing protein. (310 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
GAB2GRB2 associated binding protein 2. (709 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
CFL2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (195 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
PLPP2Phospholipid phosphatase 2. (218 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (523 aa)
F6PU44_MONDODHR-2 domain-containing protein; Belongs to the DOCK family. (930 aa)
NCF1Neutrophil cytosolic factor 1. (389 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (304 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (476 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1013 aa)
LIMK2LIM domain kinase 2. (684 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
WASWASP actin nucleation promoting factor. (504 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
F6U132_MONDOActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
PLA2G4CPLA2c domain-containing protein. (204 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LIMK1LIM domain kinase 1. (602 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (330 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CRKLUncharacterized protein. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PLA2G4EPhospholipase A2. (868 aa)
PIP5K1APIPK domain-containing protein. (630 aa)
HCKTyrosine-protein kinase. (538 aa)
GSNGelsolin. (776 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (158 aa)
LOC100015800Uncharacterized protein. (440 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLD2Phospholipase. (933 aa)
SCINUncharacterized protein. (376 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
WASF2WASP family member 2. (497 aa)
CDC42Cell division cycle 42. (191 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
K7DYV5_MONDOIg-like domain-containing protein. (295 aa)
MARCKSUncharacterized protein. (398 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1203 aa)
SPHK1Sphingosine kinase 1. (454 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1183 aa)
PLA2G6Phospholipase A2 group VI. (818 aa)
LOC100015202Ig-like domain-containing protein. (321 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (881 aa)
PLD1Phospholipase. (1035 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
WASF3WASP family member 3. (503 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
MARCKSL1Uncharacterized protein. (196 aa)
SYKTyrosine-protein kinase. (588 aa)
LYNTyrosine-protein kinase. (516 aa)
BIN1Bridging integrator 1. (613 aa)
F7GAG3_MONDOPLA2c domain-containing protein. (590 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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