STRINGSTRING
PLCB2 PLCB2 GNG12 GNG12 ADCY8 ADCY8 GNB5 GNB5 GNAI3 GNAI3 ADCY2 ADCY2 GRM5 GRM5 ADCY4 ADCY4 HOMER3 HOMER3 PRKCA PRKCA PLCB1 PLCB1 ITPR1 ITPR1 GRM7 GRM7 SLC17A8 SLC17A8 GNG10 GNG10 GRIN3B GRIN3B DLG4 DLG4 GLUL GLUL GNB1 GNB1 GRIN2C GRIN2C GNG3 GNG3 GRIA1 GRIA1 GNG8 GNG8 SLC17A6 SLC17A6 PPP3CC PPP3CC GLS GLS GNAQ GNAQ ADCY7 ADCY7 GRIK4 GRIK4 PLA2G4C PLA2G4C GRM4 GRM4 GRIN3A GRIN3A SLC1A6 SLC1A6 GRIA3 GRIA3 SLC1A1 SLC1A1 MAPK3 MAPK3 ADCY3 ADCY3 ADCY9 ADCY9 ITPR2 ITPR2 GRM1 GRM1 GNG13 GNG13 GNAI1 GNAI1 MAPK1 MAPK1 PLA2G4E PLA2G4E GRIK2 GRIK2 GNB3 GNB3 GRIN2B GRIN2B SLC38A2 SLC38A2 HOMER2 HOMER2 HOMER1 HOMER1 SLC1A2 SLC1A2 SLC1A3 SLC1A3 PPP3CA PPP3CA GRIK1 GRIK1 GLS2 GLS2 GNB4 GNB4 PLD2 PLD2 KCNJ3 KCNJ3 LOC103095126 LOC103095126 GNG7 GNG7 GNG4 GNG4 GNAI2 GNAI2 SLC1A7 SLC1A7 SHANK2 SHANK2 GRIN1 GRIN1 GRM3 GRM3 CACNA1A CACNA1A PPP3CB PPP3CB PRKCB PRKCB ADCY1 ADCY1 GRIK3 GRIK3 GRK3 GRK3 GNGT2 GNGT2 PLCB4 PLCB4 PRKACA PRKACA TRPC1 TRPC1 GRM8 GRM8 CACNA1C CACNA1C PLD1 PLD1 GNG5 GNG5 DLGAP1 DLGAP1 SLC38A3 SLC38A3 GRM6 GRM6 ITPR3 ITPR3 LOC100010184 LOC100010184 GRIN2A GRIN2A GRIA4 GRIA4 GNB2 GNB2 F7GAG3_MONDO F7GAG3_MONDO ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
GNB5G protein subunit beta 5. (353 aa)
GNAI3G protein subunit alpha i3. (399 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
GRM5Glutamate metabotropic receptor 5. (890 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
HOMER3WH1 domain-containing protein. (358 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
GRM7Glutamate metabotropic receptor 7. (714 aa)
SLC17A8MFS domain-containing protein. (323 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1019 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
GLULGlutamine synthetase. (373 aa)
GNB1G protein subunit beta 1. (340 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (902 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
GLSEF-hand_14 domain-containing protein. (248 aa)
GNAQG protein subunit alpha q. (359 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
PLA2G4CPLA2c domain-containing protein. (204 aa)
GRM4Glutamate metabotropic receptor 4. (914 aa)
GRIN3AUncharacterized protein. (1153 aa)
SLC1A6Amino acid transporter. (564 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (919 aa)
SLC1A1Amino acid transporter. (521 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (798 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNAI1G protein subunit alpha i1. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PLA2G4EPhospholipase A2. (868 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (859 aa)
GNB3G protein subunit beta 3. (340 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1463 aa)
SLC38A2Solute carrier family 38 member 2. (503 aa)
HOMER2Homer scaffold protein 2. (353 aa)
HOMER1Homer scaffold protein 1. (410 aa)
SLC1A2Amino acid transporter. (574 aa)
SLC1A3Amino acid transporter. (542 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (843 aa)
GLS2Glutaminase 2. (579 aa)
GNB4G protein subunit beta 4. (340 aa)
PLD2Phospholipase. (933 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (503 aa)
LOC103095126Aa_trans domain-containing protein. (449 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNAI2G protein subunit alpha i2. (315 aa)
SLC1A7Amino acid transporter. (155 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1202 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (938 aa)
GRM3Glutamate metabotropic receptor 3. (889 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2485 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (927 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (658 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (749 aa)
GRM8G_PROTEIN_RECEP_F3_4 domain-containing protein. (666 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
PLD1Phospholipase. (1035 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
DLGAP1DLG associated protein 1. (988 aa)
SLC38A3Solute carrier family 38 member 3. (473 aa)
GRM6Glutamate metabotropic receptor 6. (879 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
LOC100010184Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1365 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (854 aa)
GNB2G protein subunit beta 2. (367 aa)
F7GAG3_MONDOPLA2c domain-containing protein. (590 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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