STRINGSTRING
GNA12 GNA12 PLCB2 PLCB2 GUCY1A1 GUCY1A1 GNAI3 GNAI3 IGF1 IGF1 PRKCA PRKCA GNA13 GNA13 PLCB1 PLCB1 ITPR1 ITPR1 RAF1 RAF1 GRIA1 GRIA1 MAP2K1 MAP2K1 GNAZ GNAZ F7FK82_MONDO F7FK82_MONDO GNAQ GNAQ PPP1R17 PPP1R17 PLA2G4C PLA2G4C PPP2CA PPP2CA PPP2R1B PPP2R1B GRIA3 GRIA3 MAPK3 MAPK3 PRKG1 PRKG1 ITPR2 ITPR2 GRM1 GRM1 GNAI1 GNAI1 MAPK1 MAPK1 PLA2G4E PLA2G4E PPP2CB PPP2CB F7FNN8_MONDO F7FNN8_MONDO GNA11 GNA11 PRKG2 PRKG2 PPP2R1A PPP2R1A NOS1 NOS1 BRAF BRAF CRH CRH KRAS-2 KRAS-2 GNAI2 GNAI2 CACNA1A CACNA1A PRKCB PRKCB NRAS NRAS PLCB4 PLCB4 ARAF ARAF GUCY1B1 GUCY1B1 ITPR3 ITPR3 SIRT6 SIRT6 GRID2 GRID2 LYN LYN IGF1R IGF1R F7GAG3_MONDO F7GAG3_MONDO ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS HRAS HRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNA12G protein subunit alpha 12. (380 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
GNAI3G protein subunit alpha i3. (399 aa)
IGF1Insulin like growth factor 1. (225 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
GNA13G protein subunit alpha 13. (377 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (902 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
GNAZG protein subunit alpha z. (355 aa)
F7FK82_MONDOGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (667 aa)
GNAQG protein subunit alpha q. (359 aa)
PPP1R17Uncharacterized protein. (93 aa)
PLA2G4CPLA2c domain-containing protein. (204 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (627 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (919 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (455 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (798 aa)
GNAI1G protein subunit alpha i1. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PLA2G4EPhospholipase A2. (868 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
F7FNN8_MONDOUncharacterized protein. (199 aa)
GNA11G protein subunit alpha 11. (359 aa)
PRKG2cGMP-dependent protein kinase. (759 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (410 aa)
NOS1Nitric oxide synthase 1. (1464 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
CRHCorticotropin releasing hormone. (194 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
GNAI2G protein subunit alpha i2. (315 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2485 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
NRASGTPase NRas. (195 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
ARAFUncharacterized protein. (198 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (626 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
SIRT6Uncharacterized protein. (547 aa)
GRID2Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (612 aa)
LYNTyrosine-protein kinase. (516 aa)
IGF1RTyrosine-protein kinase receptor. (1259 aa)
F7GAG3_MONDOPLA2c domain-containing protein. (590 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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