STRINGSTRING
CCKAR CCKAR PLCB2 PLCB2 CREB3L3 CREB3L3 ADCY8 ADCY8 ADCY2 ADCY2 ATP1B1 ATP1B1 ADCY4 ADCY4 RAB3A RAB3A PRKCA PRKCA PLCB1 PLCB1 SNAP25 SNAP25 GCG GCG ABCC8 ABCC8 KCNJ11 KCNJ11 ATP1B2 ATP1B2 CREB3 CREB3 PDX1 PDX1 ATF4 ATF4 ATF2 ATF2 CCK CCK GNAQ GNAQ ADCY7 ADCY7 GLP1R GLP1R STX1A STX1A CREB3L2 CREB3L2 FFAR1 FFAR1 ATF6B ATF6B CREB5 CREB5 KCNN2 KCNN2 ADCY3 ADCY3 SLC2A2 SLC2A2 CAMK2B CAMK2B ADCY9 ADCY9 PCLO PCLO SLC2A1 SLC2A1 CREB3L4 CREB3L4 GNA11 GNA11 GPR119 GPR119 KCNMB4 KCNMB4 KCNMB3 KCNMB3 KCNMB2 KCNMB2 CHRM3 CHRM3 CACNA1S CACNA1S FXYD2 FXYD2 GIP GIP KCNMA1 KCNMA1 ADCYAP1R1 ADCYAP1R1 CREB3L1 CREB3L1 PRKCB PRKCB ADCY1 ADCY1 RYR2 RYR2 GCK GCK VAMP2 VAMP2 PLCB4 PLCB4 PRKACA PRKACA KCNMB1 KCNMB1 RIMS2 RIMS2 RAPGEF4 RAPGEF4 CACNA1C CACNA1C KCNU1 KCNU1 ADCYAP1 ADCYAP1 ITPR3 ITPR3 KCNN1 KCNN1 CAMK2D CAMK2D CREB1 CREB1 ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (429 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (508 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (304 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
RAB3ARAB3A, member RAS oncogene family. (346 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
GCGGlucagon. (181 aa)
ABCC8ATP binding cassette subfamily C member 8. (1580 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (399 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CREB3BZIP domain-containing protein. (370 aa)
PDX1Homeobox domain-containing protein. (290 aa)
ATF4Activating transcription factor 4. (346 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CCKGastrin domain-containing protein. (126 aa)
GNAQG protein subunit alpha q. (359 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (464 aa)
STX1ASyntaxin 1A. (324 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (518 aa)
FFAR1Free fatty acid receptor 1. (299 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (504 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (850 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (518 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (671 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
PCLOUncharacterized protein. (1220 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (360 aa)
GNA11G protein subunit alpha 11. (359 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (332 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (284 aa)
KCNMB2Uncharacterized protein. (228 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (585 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (123 aa)
GIPGLUCAGON domain-containing protein. (144 aa)
KCNMA1BK_channel_a domain-containing protein. (189 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (535 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
RYR2Ryanodine receptor 2. (4900 aa)
GCKPhosphotransferase. (532 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (152 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
KCNMB1Uncharacterized protein. (203 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1748 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (912 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1201 aa)
ADCYAP1GLUCAGON domain-containing protein. (193 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (580 aa)
CAMK2DProtein kinase domain-containing protein. (145 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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