61 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLCA1	VWFA domain-containing protein. (841 aa)
	CLCA2	Chloride channel accessory 2. (947 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	LOC100017048	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (389 aa)
	GUCY1A1	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
	GNAI3	G protein subunit alpha i3. (399 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
	ADRB2	Adrenoceptor beta 2. (393 aa)
	H9H690_MONDO	Uncharacterized protein. (352 aa)
	PDE3B	Phosphodiesterase. (1156 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (469 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (517 aa)
	CALML4	Calmodulin like 4. (156 aa)
	ADRB1	Adrenoceptor beta 1. (505 aa)
	EDN1	Endothelin 1. (214 aa)
	F7FK82_MONDO	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (667 aa)
	ADRB3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (518 aa)
	NPPA	Natriuretic peptide A. (160 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (337 aa)
	GNAQ	G protein subunit alpha q. (359 aa)
	PDE1C	Phosphodiesterase. (619 aa)
	PTGER2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	NPR1	Guanylate cyclase. (904 aa)
	PDE3A	Phosphodiesterase. (1169 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (521 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PRKG2	cGMP-dependent protein kinase. (759 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (141 aa)
	F7D7P9_MONDO	Uncharacterized protein; Belongs to the calmodulin family. (65 aa)
	KCNJ2	Potassium voltage-gated channel subfamily J member 2. (427 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
	F6R2Y0_MONDO	VWFA domain-containing protein. (466 aa)
	F6XDP7_MONDO	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (391 aa)
	LOC100017089	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (391 aa)
	LOC100016857	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (389 aa)
	EDN2	Uncharacterized protein. (178 aa)
	KCNMA1	BK_channel_a domain-containing protein. (189 aa)
	GNAI2	G protein subunit alpha i2. (315 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (520 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
	ORAI1	Uncharacterized protein. (314 aa)
	GUCY1B1	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (626 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
	ADCYAP1	GLUCAGON domain-containing protein. (193 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
	PDE1A	Phosphodiesterase. (878 aa)
	ENSMODP00000056926	VWFA domain-containing protein. (897 aa)
	EDN3	Uncharacterized protein. (219 aa)
	CREB1	cAMP responsive element binding protein 1. (327 aa)
	ENSMODP00000059741	Uncharacterized protein. (70 aa)
	GNAS	Uncharacterized protein. (370 aa)
	LOC100009811	VWFA domain-containing protein. (918 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1	ADCYAP1R1	ENSMODP00000052641	ENSMODP00000043365	GLUCAGON domain-containing protein.	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	0.998
ADCYAP1	ADRB1	ENSMODP00000052641	ENSMODP00000012311	GLUCAGON domain-containing protein.	Adrenoceptor beta 1.	0.922
ADCYAP1	CREB1	ENSMODP00000052641	ENSMODP00000059251	GLUCAGON domain-containing protein.	cAMP responsive element binding protein 1.	0.403
ADCYAP1	ENSMODP00000059741	ENSMODP00000052641	ENSMODP00000059741	GLUCAGON domain-containing protein.	Uncharacterized protein.	0.410
ADCYAP1	GNAS	ENSMODP00000052641	ENSMODP00000059778	GLUCAGON domain-containing protein.	Uncharacterized protein.	0.569
ADCYAP1	NPR1	ENSMODP00000052641	ENSMODP00000021667	GLUCAGON domain-containing protein.	Guanylate cyclase.	0.901
ADCYAP1	PTGER2	ENSMODP00000052641	ENSMODP00000018085	GLUCAGON domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.906
ADCYAP1R1	ADCYAP1	ENSMODP00000043365	ENSMODP00000052641	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	GLUCAGON domain-containing protein.	0.998
ADCYAP1R1	AQP1	ENSMODP00000043365	ENSMODP00000026101	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.564
ADCYAP1R1	ENSMODP00000059741	ENSMODP00000043365	ENSMODP00000059741	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.959
ADCYAP1R1	GNAQ	ENSMODP00000043365	ENSMODP00000016195	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	G protein subunit alpha q.	0.934
ADCYAP1R1	GNAS	ENSMODP00000043365	ENSMODP00000059778	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.959
ADCYAP1R1	NPPA	ENSMODP00000043365	ENSMODP00000013664	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Natriuretic peptide A.	0.900
ADRB1	ADCYAP1	ENSMODP00000012311	ENSMODP00000052641	Adrenoceptor beta 1.	GLUCAGON domain-containing protein.	0.922
ADRB1	ADRB2	ENSMODP00000012311	ENSMODP00000006999	Adrenoceptor beta 1.	Adrenoceptor beta 2.	0.900
ADRB1	ADRB3	ENSMODP00000012311	ENSMODP00000013507	Adrenoceptor beta 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.958
ADRB1	AGTR1	ENSMODP00000012311	ENSMODP00000035452	Adrenoceptor beta 1.	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.440
ADRB1	ENSMODP00000059741	ENSMODP00000012311	ENSMODP00000059741	Adrenoceptor beta 1.	Uncharacterized protein.	0.964
ADRB1	GNAI1	ENSMODP00000012311	ENSMODP00000021359	Adrenoceptor beta 1.	G protein subunit alpha i1.	0.929
ADRB1	GNAI2	ENSMODP00000012311	ENSMODP00000041761	Adrenoceptor beta 1.	G protein subunit alpha i2.	0.929