STRINGSTRING
PRKCE PRKCE SOCS3 SOCS3 PKM PKM PIK3R3 PIK3R3 HK3 HK3 SLC2A4 SLC2A4 ABCC8 ABCC8 KCNJ11 KCNJ11 PDX1 PDX1 IKBKB IKBKB HK1 HK1 PRKCD PRKCD HKDC1 HKDC1 HK2 HK2 MAFA MAFA ADIPOQ ADIPOQ INSR INSR MAPK3 MAPK3 SLC2A2 SLC2A2 PKLR PKLR MAPK1 MAPK1 PIK3R1 PIK3R1 MAPK10 MAPK10 PIK3CA PIK3CA LOC100617582 LOC100617582 MAPK9 MAPK9 IRS1 IRS1 F6TU13_MONDO F6TU13_MONDO IRS2 IRS2 K7E1M2_MONDO K7E1M2_MONDO PRKCZ PRKCZ CACNA1A CACNA1A GCK GCK CACNA1C CACNA1C PIK3CB PIK3CB MTOR MTOR SOCS2 SOCS2 SOCS4 SOCS4 CACNA1G CACNA1G
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCEProtein kinase domain-containing protein. (212 aa)
SOCS3Suppressor of cytokine signaling 3. (235 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (635 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
HK3Hexokinase 3. (1049 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
ABCC8ATP binding cassette subfamily C member 8. (1580 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (399 aa)
PDX1Homeobox domain-containing protein. (290 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
HK1Hexokinase 1. (922 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK2Hexokinase 2. (932 aa)
MAFAMAF bZIP transcription factor A. (336 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (256 aa)
INSRTyrosine-protein kinase receptor. (1378 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (518 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (569 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100617582Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IRS1Insulin receptor substrate 1. (1243 aa)
F6TU13_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
IRS2Insulin receptor substrate 2. (1384 aa)
K7E1M2_MONDOUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2485 aa)
GCKPhosphotransferase. (532 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
SOCS2Suppressor of cytokine signaling 2. (234 aa)
SOCS4Suppressor of cytokine signaling 4. (436 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2345 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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