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PLCB2 PLCB2 ADCY8 ADCY8 GNAI3 GNAI3 ADCY2 ADCY2 SLC9A4 SLC9A4 CALM1 CALM1 ATP1B1 ATP1B1 ADCY4 ADCY4 PRKCA PRKCA SLC4A2 SLC4A2 PLCB1 PLCB1 ITPR1 ITPR1 KCNJ1 KCNJ1 ATP1B2 ATP1B2 SLC26A7 SLC26A7 SST SST CALML4 CALML4 LOC100028958 LOC100028958 MYLK3 MYLK3 GNAQ GNAQ ADCY7 ADCY7 ATP4A ATP4A SLC9A1 SLC9A1 GAST GAST CFTR CFTR ADCY3 ADCY3 CAMK2B CAMK2B ADCY9 ADCY9 ITPR2 ITPR2 GNAI1 GNAI1 MYLK MYLK F7D7P9_MONDO F7D7P9_MONDO LOC100016601 LOC100016601 KCNJ16 KCNJ16 KCNJ2 KCNJ2 SSTR2 SSTR2 KCNJ10 KCNJ10 CHRM3 CHRM3 CALML3 CALML3 LOC100020439 LOC100020439 KCNE2 KCNE2 KCNJ15 KCNJ15 LOC100025850 LOC100025850 GNAI2 GNAI2 CCKBR CCKBR ACTG1 ACTG1 PRKCB PRKCB ADCY1 ADCY1 MYLK4 MYLK4 EZR EZR KCNK2 KCNK2 PLCB4 PLCB4 PRKACA PRKACA KCNK10 KCNK10 ITPR3 ITPR3 HRH2 HRH2 CAMK2D CAMK2D ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
GNAI3G protein subunit alpha i3. (399 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (304 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
SLC4A2Anion exchange protein. (1221 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (379 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
SLC26A7Anion exchange transporter. (656 aa)
SSTSomatostatin. (116 aa)
CALML4Calmodulin like 4. (156 aa)
LOC100028958Uncharacterized protein. (375 aa)
MYLK3Myosin light chain kinase 3. (846 aa)
GNAQG protein subunit alpha q. (359 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1032 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (392 aa)
GASTGastrin. (100 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (671 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
GNAI1G protein subunit alpha i1. (354 aa)
MYLKMyosin light chain kinase. (1948 aa)
F7D7P9_MONDOUncharacterized protein; Belongs to the calmodulin family. (65 aa)
LOC100016601Uncharacterized protein. (374 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (422 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (585 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LOC100020439Uncharacterized protein; Belongs to the actin family. (374 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (442 aa)
LOC100025850Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (265 aa)
GNAI2G protein subunit alpha i2. (315 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (468 aa)
ACTG1Uncharacterized protein. (375 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
MYLK4Protein kinase domain-containing protein. (690 aa)
EZREzrin. (587 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (447 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (534 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (460 aa)
CAMK2DProtein kinase domain-containing protein. (145 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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