44 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)
	VDAC2	Voltage dependent anion channel 2. (283 aa)
	ANGPTL3	Angiopoietin like 3. (461 aa)
	SORT1	Sortilin. (693 aa)
	LRPAP1	LDL receptor related protein associated protein 1. (366 aa)
	LIPG	Lipase G, endothelial type. (504 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (618 aa)
	APOH	Apolipoprotein H. (345 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (459 aa)
	LDLR	Low density lipoprotein receptor. (906 aa)
	ANGPTL8	Uncharacterized protein. (251 aa)
	TSPO	Uncharacterized protein. (275 aa)
	ABCB11	ATP binding cassette subfamily B member 11. (1322 aa)
	LRP2	LDL receptor related protein 2. (4605 aa)
	LIPC	Lipase C, hepatic type. (524 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (505 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (479 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (338 aa)
	MYLIP	Myosin regulatory light chain interacting protein. (445 aa)
	STARD3	StAR related lipid transfer domain containing 3. (446 aa)
	CETP	Cholesteryl ester transfer protein. (511 aa)
	APOA4	Uncharacterized protein. (371 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (307 aa)
	VDAC1	Voltage dependent anion channel 1. (400 aa)
	SOAT1	O-acyltransferase. (555 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (543 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2260 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (471 aa)
	APOC1	Uncharacterized protein. (89 aa)
	VAPA	MSP domain-containing protein. (235 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1281 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (671 aa)
	ANGPTL4	Angiopoietin like 4. (454 aa)
	APOC3	Uncharacterized protein. (100 aa)
	NCEH1	Uncharacterized protein. (416 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (519 aa)
	OSBPL5	Oxysterol-binding protein; Belongs to the OSBP family. (885 aa)
	NPC2	ML domain-containing protein. (265 aa)
	VAPB	VAMP associated protein B and C. (243 aa)
	APOB	Uncharacterized protein. (3161 aa)
	VDAC3	Uncharacterized protein. (284 aa)
	ENSMODP00000057233	MSP domain-containing protein. (142 aa)
	APOE	Uncharacterized protein. (299 aa)
	APOA1	Uncharacterized protein. (264 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSMODP00000020336	ENSMODP00000059859	ATP binding cassette subfamily A member 1.	Uncharacterized protein.	0.933
ABCA1	APOE	ENSMODP00000020336	ENSMODP00000057511	ATP binding cassette subfamily A member 1.	Uncharacterized protein.	0.441
ABCA1	SCARB1	ENSMODP00000020336	ENSMODP00000044237	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.417
ABCB11	ABCG5	ENSMODP00000009711	ENSMODP00000000677	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 5.	0.474
ABCB11	ABCG8	ENSMODP00000009711	ENSMODP00000028394	ATP binding cassette subfamily B member 11.	ATP binding cassette subfamily G member 8.	0.470
ABCB11	CYP27A1	ENSMODP00000009711	ENSMODP00000019193	ATP binding cassette subfamily B member 11.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.531
ABCB11	CYP7A1	ENSMODP00000009711	ENSMODP00000011028	ATP binding cassette subfamily B member 11.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.727
ABCG5	ABCB11	ENSMODP00000000677	ENSMODP00000009711	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily B member 11.	0.474
ABCG5	ABCG8	ENSMODP00000000677	ENSMODP00000028394	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	APOB	ENSMODP00000000677	ENSMODP00000054373	ATP binding cassette subfamily G member 5.	Uncharacterized protein.	0.450
ABCG5	CD36	ENSMODP00000000677	ENSMODP00000021313	ATP binding cassette subfamily G member 5.	CD36 molecule; Belongs to the CD36 family.	0.412
ABCG5	CYP27A1	ENSMODP00000000677	ENSMODP00000019193	ATP binding cassette subfamily G member 5.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.512
ABCG5	CYP7A1	ENSMODP00000000677	ENSMODP00000011028	ATP binding cassette subfamily G member 5.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.715
ABCG5	SCARB1	ENSMODP00000000677	ENSMODP00000044237	ATP binding cassette subfamily G member 5.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.406
ABCG8	ABCB11	ENSMODP00000028394	ENSMODP00000009711	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily B member 11.	0.470
ABCG8	ABCG5	ENSMODP00000028394	ENSMODP00000000677	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	APOB	ENSMODP00000028394	ENSMODP00000054373	ATP binding cassette subfamily G member 8.	Uncharacterized protein.	0.407
ABCG8	CYP27A1	ENSMODP00000028394	ENSMODP00000019193	ATP binding cassette subfamily G member 8.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.537
ABCG8	CYP7A1	ENSMODP00000028394	ENSMODP00000011028	ATP binding cassette subfamily G member 8.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.677
ABCG8	SCARB1	ENSMODP00000028394	ENSMODP00000044237	ATP binding cassette subfamily G member 8.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.406