STRINGSTRING
NDUFC1 NDUFC1 TGM2 TGM2 COX7A2L COX7A2L PLCB2 PLCB2 PPARGC1A PPARGC1A GPX7 GPX7 SDHA SDHA LOC100015203 LOC100015203 CREB3L3 CREB3L3 VDAC2 VDAC2 PPIF PPIF NDUFA11 NDUFA11 DNAH11 DNAH11 DNAH17 DNAH17 PSMA5 PSMA5 LOC100010487 LOC100010487 PSMD2 PSMD2 NDUFB7 NDUFB7 CLTA CLTA PSMD7 PSMD7 PSMC1 PSMC1 GRM5 GRM5 DNAH5 DNAH5 PSMD6 PSMD6 COX6A1 COX6A1 ATP5F1A ATP5F1A TUBB3 TUBB3 HTT HTT PSMD12 PSMD12 NDUFA3 NDUFA3 UQCR11 UQCR11 PLCB1 PLCB1 ITPR1 ITPR1 CASP3 CASP3 NDUFB6 NDUFB6 COX4I1 COX4I1 SLC25A4 SLC25A4 PSMB5 PSMB5 CLTB CLTB PSMD14 PSMD14 TBP TBP POLR2E POLR2E PSMB6 PSMB6 PSMB1 PSMB1 PPARG PPARG LOC100030489 LOC100030489 DLG4 DLG4 DNAL1 DNAL1 POLR2A POLR2A NDUFA6 NDUFA6 NDUFA13 NDUFA13 CREB3 CREB3 PSMA1 PSMA1 DNAH2 DNAH2 SOD2 SOD2 TBPL2 TBPL2 MAP3K10 MAP3K10 NDUFA10 NDUFA10 KIF5B KIF5B ACTR10 ACTR10 PSMA3 PSMA3 DNAI1 DNAI1 KLC2 KLC2 GRIA1 GRIA1 ATP5MC3 ATP5MC3 RB1CC1 RB1CC1 GPX2 GPX2 CLTCL1 CLTCL1 NDUFA1 NDUFA1 CYC1 CYC1 ULK2 ULK2 ACTR1A ACTR1A NDUFA2 NDUFA2 DNAH1 DNAH1 PSMA4 PSMA4 F7AM90_MONDO F7AM90_MONDO PIK3R4 PIK3R4 DNAH7 DNAH7 SLC25A31 SLC25A31 PSMB3 PSMB3 UQCRFS1 UQCRFS1 PSMA6 PSMA6 ATG2B ATG2B GNAQ GNAQ GPX1 GPX1 PSMD3 PSMD3 POLR2C POLR2C POLR2J POLR2J PSMC4 PSMC4 STX1A STX1A LOC100015788 LOC100015788 CREB3L2 CREB3L2 COX6B1 COX6B1 NDUFA4 NDUFA4 VDAC1 VDAC1 POLR2I POLR2I PSMC6 PSMC6 NRF1 NRF1 MAP2K7 MAP2K7 GRIA3 GRIA3 BECN1 BECN1 CASP8 CASP8 LOC100010481 LOC100010481 CREB5 CREB5 TUBB TUBB COX5B COX5B ACTR1B ACTR1B NDUFB10 NDUFB10 TFAM TFAM NDUFAB1 NDUFAB1 CREBBP CREBBP TUBB1 TUBB1 ATP5F1E ATP5F1E TAF4 TAF4 NRBF2 NRBF2 PSMC2 PSMC2 CREB3L4 CREB3L4 TRAF2 TRAF2 MAP3K5 MAP3K5 HDAC1 HDAC1 TBPL1 TBPL1 HDAC2 HDAC2 PSMB2 PSMB2 IFT57 IFT57 GRIN2B GRIN2B NDUFA9 NDUFA9 TUBA8 TUBA8 NDUFB11 NDUFB11 F7B3U4_MONDO F7B3U4_MONDO POLR2D POLR2D KLC4 KLC4 POLR2F POLR2F AP2B1 AP2B1 PSMD11 PSMD11 NDUFA8 NDUFA8 PSMB7 PSMB7 SLC1A2 SLC1A2 ATP5F1B ATP5F1B PSMC3 PSMC3 NDUFS3 NDUFS3 SLC1A3 SLC1A3 MAPK10 MAPK10 ATP5PF ATP5PF NDUFV3 NDUFV3 SOD1 SOD1 NDUFB5 NDUFB5 NDUFV1 NDUFV1 TUBB6 TUBB6 PSMA8 PSMA8 TAF4B TAF4B ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB H9H824_MONDO H9H824_MONDO H9H9I1_MONDO H9H9I1_MONDO PSMA7 PSMA7 F7BQU1_MONDO F7BQU1_MONDO MAPK9 MAPK9 LOC100024672 LOC100024672 WIPI1 WIPI1 ATG13 ATG13 KCNJ10 KCNJ10 WIPI2 WIPI2 LOC100018337 LOC100018337 LOC100016464 LOC100016464 SIN3A SIN3A F7BFL6_MONDO F7BFL6_MONDO EP300 EP300 F6U2Q2_MONDO F6U2Q2_MONDO PSMD9 PSMD9 POLR2B POLR2B CASP18 CASP18 POLR2G POLR2G LOC100026811 LOC100026811 BBC3 BBC3 CLTC CLTC POLR2H POLR2H NDUFS5 NDUFS5 UQCRC1 UQCRC1 GPX3 GPX3 ATP5F1C ATP5F1C LOC100026672 LOC100026672 KLC1 KLC1 DCTN4 DCTN4 PSMD4 PSMD4 GRIN1 GRIN1 PSMD1 PSMD1 ATP5MC1 ATP5MC1 CREB3L1 CREB3L1 DNAH10 DNAH10 NDUFA5 NDUFA5 ENSMODP00000045334 ENSMODP00000045334 PSMA2 PSMA2 ATP5PD ATP5PD BDNF BDNF PIK3C3 PIK3C3 LOC654275 LOC654275 SDHC SDHC LOC100030139 LOC100030139 PSMC5 PSMC5 NDUFS2 NDUFS2 DCTN3 DCTN3 AMBRA1 AMBRA1 NDUFB1 NDUFB1 DNAI2 DNAI2 NDUFV2 NDUFV2 NDUFS1 NDUFS1 LOC100020481 LOC100020481 NDUFB4 NDUFB4 PLCB4 PLCB4 BAX BAX TUBA1B TUBA1B NDUFC2 NDUFC2 NDUFA7 NDUFA7 PSMD8 PSMD8 ENSMODP00000050493 ENSMODP00000050493 NDUFB8 NDUFB8 TUBB4B TUBB4B DNAH8 DNAH8 DCTN1 DCTN1 DNALI1 DNALI1 ENSMODP00000051940 ENSMODP00000051940 AP2S1 AP2S1 NDUFB9 NDUFB9 DNAH9 DNAH9 ADRM1 ADRM1 KIF5C KIF5C RCOR1 RCOR1 TUBB2A TUBB2A NDUFS4 NDUFS4 GPX8 GPX8 HIP1 HIP1 AP2M1 AP2M1 NDUFS8 NDUFS8 PSMD13 PSMD13 SDHB SDHB DNAH3 DNAH3 DCTN6 DCTN6 NDUFS7 NDUFS7 SDHD SDHD VDAC3 VDAC3 ENSMODP00000057502 ENSMODP00000057502 LOC100012494 LOC100012494 REST REST MTOR MTOR GRIA4 GRIA4 CYCS CYCS CREB1 CREB1 ENSMODP00000059492 ENSMODP00000059492 DNAH6 DNAH6 POLR2K POLR2K ENSMODP00000060103 ENSMODP00000060103 DCTN5 DCTN5 APAF1 APAF1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (77 aa)
TGM2Transglutaminase 2. (689 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
PPARGC1APPARG coactivator 1 alpha. (795 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (157 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
LOC100015203Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (508 aa)
VDAC2Voltage dependent anion channel 2. (283 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
NDUFA11Uncharacterized protein. (141 aa)
DNAH11Dynein axonemal heavy chain 11. (4386 aa)
DNAH17Uncharacterized protein. (803 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
LOC100010487Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (928 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (124 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (357 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
GRM5Glutamate metabotropic receptor 5. (890 aa)
DNAH5Dynein axonemal heavy chain 5. (4610 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (112 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
HTTHuntingtin. (2899 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (80 aa)
UQCR11Uncharacterized protein. (56 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (127 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMB5Proteasome subunit beta. (263 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
TBPTATA-box binding protein. (308 aa)
POLR2ERNA polymerase II subunit E. (221 aa)
PSMB6Proteasome subunit beta. (246 aa)
PSMB1Proteasome subunit beta. (244 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (486 aa)
LOC100030489COX6C domain-containing protein. (75 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
DNAL1Uncharacterized protein. (477 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
CREB3BZIP domain-containing protein. (370 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
DNAH2Dynein axonemal heavy chain 2. (4352 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
TBPL2TATA-box binding protein like 2. (342 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (966 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (363 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (461 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
DNAI1Dynein axonemal intermediate chain 1. (698 aa)
KLC2TPR_REGION domain-containing protein. (522 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (902 aa)
ATP5MC3ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1556 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (64 aa)
CYC1Cytochrome c1. (320 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1041 aa)
ACTR1AActin related protein 1A. (376 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (100 aa)
DNAH1Dynein axonemal heavy chain 1. (4127 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
F7AM90_MONDOTAFH domain-containing protein. (597 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1410 aa)
DNAH7Dynein axonemal heavy chain 7. (3998 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
PSMB3Proteasome subunit beta. (205 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ATG2BAutophagy related 2B. (1880 aa)
GNAQG protein subunit alpha q. (359 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (540 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
STX1ASyntaxin 1A. (324 aa)
LOC100015788Uncharacterized protein. (82 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (518 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
VDAC1Voltage dependent anion channel 1. (400 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
NRF1Nuclear respiratory factor 1. (503 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (919 aa)
BECN1Uncharacterized protein. (448 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (472 aa)
LOC100010481Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (504 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
COX5BCytochrome c oxidase subunit 5B. (128 aa)
ACTR1BActin related protein 1B. (376 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
TFAMUncharacterized protein. (259 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
CREBBPCREB binding protein. (2456 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ATP5F1EUncharacterized protein. (51 aa)
TAF4TAFH domain-containing protein. (1113 aa)
NRBF2Nuclear receptor binding factor 2. (277 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (420 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (360 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1390 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
PSMB2Uncharacterized protein. (83 aa)
IFT57Intraflagellar transport 57. (431 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1463 aa)
NDUFA9Epimerase domain-containing protein. (377 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (157 aa)
F7B3U4_MONDOUncharacterized protein. (108 aa)
POLR2DRPOL4c domain-containing protein. (142 aa)
KLC4Kinesin light chain 4. (611 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
AP2B1AP complex subunit beta. (951 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (451 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
PSMB7Proteasome subunit beta. (277 aa)
SLC1A2Amino acid transporter. (574 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (525 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (437 aa)
NDUFS3Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (539 aa)
SLC1A3Amino acid transporter. (542 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
NDUFV3Uncharacterized protein. (421 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (177 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (195 aa)
NDUFV1NADH:ubiquinone oxidoreductase core subunit V1. (438 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
TAF4BTATA-box binding protein associated factor 4b. (978 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (228 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (116 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (608 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (166 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (382 aa)
H9H824_MONDONADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (114 aa)
H9H9I1_MONDOUncharacterized protein. (82 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
F7BQU1_MONDOCytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (83 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC100024672Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (439 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (449 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (554 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
WIPI2Uncharacterized protein. (436 aa)
LOC100018337Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
LOC100016464Proteasome subunit beta. (183 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
F7BFL6_MONDOUncharacterized protein. (88 aa)
EP300E1A binding protein p300. (2454 aa)
F6U2Q2_MONDOUncharacterized protein. (116 aa)
PSMD9Uncharacterized protein. (228 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
CASP18Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
LOC100026811Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
BBC3Uncharacterized protein. (318 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
NDUFS5Uncharacterized protein. (171 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (511 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (238 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
LOC100026672Uncharacterized protein. (455 aa)
KLC1Uncharacterized protein. (637 aa)
DCTN4Dynactin subunit 4. (467 aa)
PSMD4VWFA domain-containing protein. (453 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (938 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1253 aa)
ATP5MC1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (535 aa)
DNAH10Dynein axonemal heavy chain 10. (4510 aa)
NDUFA5Uncharacterized protein. (133 aa)
ENSMODP00000045334Uncharacterized protein. (74 aa)
PSMA2Proteasome endopeptidase complex. (313 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (285 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
LOC100030139Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
PSMC5AAA domain-containing protein; Belongs to the AAA ATPase family. (502 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (480 aa)
DCTN3Dynactin subunit 3. (203 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1230 aa)
NDUFB1Uncharacterized protein. (58 aa)
DNAI2Dynein axonemal intermediate chain 2. (660 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (279 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (726 aa)
LOC100020481Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (78 aa)
NDUFB4Uncharacterized protein. (127 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
BAXUncharacterized protein. (296 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
NDUFA7Uncharacterized protein. (186 aa)
PSMD8PCI domain-containing protein. (283 aa)
ENSMODP00000050493Uncharacterized protein. (105 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (483 aa)
DNAH8Dynein axonemal heavy chain 8. (4711 aa)
DCTN1CAP-Gly domain-containing protein. (1270 aa)
DNALI1Dynein axonemal light intermediate chain 1. (163 aa)
ENSMODP00000051940Uncharacterized protein. (70 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (150 aa)
NDUFB9Uncharacterized protein; Belongs to the complex I LYR family. (249 aa)
DNAH9Dynein axonemal heavy chain 9. (4481 aa)
ADRM1Adhesion regulating molecule 1. (406 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (992 aa)
RCOR1REST corepressor 1. (500 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
NDUFS4Uncharacterized protein. (180 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
HIP1Huntingtin interacting protein 1. (1030 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (437 aa)
NDUFS84Fe-4S ferredoxin-type domain-containing protein. (64 aa)
PSMD13Uncharacterized protein. (203 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
DNAH3Dynein axonemal heavy chain 3. (4054 aa)
DCTN6Uncharacterized protein. (273 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (215 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
VDAC3Uncharacterized protein. (284 aa)
ENSMODP00000057502Uncharacterized protein. (201 aa)
LOC100012494Cytochrome c oxidase subunit 6A, mitochondrial. (152 aa)
RESTRE1 silencing transcription factor. (973 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (854 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ENSMODP00000059492Uncharacterized protein. (77 aa)
DNAH6Dynein axonemal heavy chain 6. (4131 aa)
POLR2KUncharacterized protein. (58 aa)
ENSMODP00000060103Uncharacterized protein. (92 aa)
DCTN5Dynactin subunit 5. (199 aa)
APAF1Apoptotic peptidase activating factor 1. (1279 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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