STRINGSTRING
NDUFC1 NDUFC1 COX7A2L COX7A2L SDHA SDHA RAC2 RAC2 LOC100015203 LOC100015203 NCF4 NCF4 CREB3L3 CREB3L3 VDAC2 VDAC2 PPIF PPIF IL6 IL6 NDUFA11 NDUFA11 PSMA5 PSMA5 PIK3R3 PIK3R3 LOC100010487 LOC100010487 PSMD2 PSMD2 NDUFB7 NDUFB7 PSMD7 PSMD7 PSMC1 PSMC1 PSMD6 PSMD6 COX6A1 COX6A1 ATP5F1A ATP5F1A TUBB3 TUBB3 PSMD12 PSMD12 NDUFA3 NDUFA3 UQCR11 UQCR11 CYBA CYBA ITPR1 ITPR1 CASP3 CASP3 NDUFB6 NDUFB6 COX4I1 COX4I1 SLC25A4 SLC25A4 PSMB5 PSMB5 PSMD14 PSMD14 PSMB6 PSMB6 PSMB1 PSMB1 GRIN3B GRIN3B HSPA1A HSPA1A LOC100030489 LOC100030489 GRIN2C GRIN2C NCF1 NCF1 LAMC1 LAMC1 NDUFA6 NDUFA6 NCF2 NCF2 NDUFA13 NDUFA13 CREB3 CREB3 PSMA1 PSMA1 NDUFA10 NDUFA10 KIF5B KIF5B PSMA3 PSMA3 KLC2 KLC2 ATF4 ATF4 PPP3CC PPP3CC ATF2 ATF2 ATP5MC3 ATP5MC3 EIF2AK3 EIF2AK3 EIF2S1 EIF2S1 NDUFA1 NDUFA1 CYC1 CYC1 PRKCD PRKCD NDUFA2 NDUFA2 PSMA4 PSMA4 SLC25A31 SLC25A31 PSMB3 PSMB3 UQCRFS1 UQCRFS1 PSMA6 PSMA6 PSMD3 PSMD3 MAPK13 MAPK13 PSMC4 PSMC4 IL1B IL1B LOC100015788 LOC100015788 CREB3L2 CREB3L2 COX6B1 COX6B1 NDUFA4 NDUFA4 VDAC1 VDAC1 GRIN3A GRIN3A PSMC6 PSMC6 ATF6B ATF6B LOC100010481 LOC100010481 CREB5 CREB5 MAPK3 MAPK3 CAV1 CAV1 TUBB TUBB COX5B COX5B NDUFB10 NDUFB10 C1QC C1QC NDUFAB1 NDUFAB1 TUBB1 TUBB1 ITPR2 ITPR2 ATP5F1E ATP5F1E PSMC2 PSMC2 CREB3L4 CREB3L4 C8G C8G MAPK1 MAPK1 PSMB2 PSMB2 GRIN2B GRIN2B NDUFA9 NDUFA9 TUBA8 TUBA8 NDUFB11 NDUFB11 F7B3U4_MONDO F7B3U4_MONDO KLC4 KLC4 CCL5 CCL5 PSMD11 PSMD11 CSNK2A1 CSNK2A1 C5 C5 NDUFA8 NDUFA8 PIK3R1 PIK3R1 PSMB7 PSMB7 HSPA5 HSPA5 ATP5F1B ATP5F1B PSMC3 PSMC3 NDUFS3 NDUFS3 C6 C6 C7 C7 C9 C9 PPP3CA PPP3CA MAPK10 MAPK10 ATP5PF ATP5PF NDUFV3 NDUFV3 SOD1 SOD1 CYBB CYBB NDUFB5 NDUFB5 PIK3CA PIK3CA NDUFV1 NDUFV1 TUBB6 TUBB6 PSMA8 PSMA8 ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB H9H824_MONDO H9H824_MONDO H9H9I1_MONDO H9H9I1_MONDO PSMA7 PSMA7 F7BQU1_MONDO F7BQU1_MONDO MAPK9 MAPK9 LOC100024672 LOC100024672 CACNA1S CACNA1S LOC100018337 LOC100018337 LOC100011711 LOC100011711 LOC100015032 LOC100015032 LOC100016464 LOC100016464 F7BFL6_MONDO F7BFL6_MONDO F6U2Q2_MONDO F6U2Q2_MONDO PSMD9 PSMD9 LOC100026811 LOC100026811 LOC100032606 LOC100032606 NDUFS5 NDUFS5 UQCRC1 UQCRC1 ATP5F1C ATP5F1C LOC100026672 LOC100026672 KLC1 KLC1 PSMD4 PSMD4 CSNK2A2 CSNK2A2 GRIN1 GRIN1 PSMD1 PSMD1 BAD BAD ATP5MC1 ATP5MC1 CREB3L1 CREB3L1 CAV2 CAV2 NDUFA5 NDUFA5 NCAM2 NCAM2 PPP3CB PPP3CB ENSMODP00000045334 ENSMODP00000045334 PRNP PRNP PSMA2 PSMA2 ATP5PD ATP5PD NCAM1 NCAM1 RYR2 RYR2 LOC654275 LOC654275 SDHC SDHC LOC100030139 LOC100030139 PSMC5 PSMC5 NDUFS2 NDUFS2 MAPK14 MAPK14 LOC100032604 LOC100032604 NDUFB1 NDUFB1 NDUFV2 NDUFV2 NDUFS1 NDUFS1 LOC100020481 LOC100020481 NDUFB4 NDUFB4 PRKACA PRKACA C1QB C1QB BAX BAX TUBA1B TUBA1B RYR3 RYR3 NDUFC2 NDUFC2 NDUFA7 NDUFA7 PSMD8 PSMD8 CAV3 CAV3 C1QA C1QA ENSMODP00000050493 ENSMODP00000050493 NDUFB8 NDUFB8 CACNA1C CACNA1C TUBB4B TUBB4B MCU MCU CSNK2B CSNK2B ENSMODP00000051940 ENSMODP00000051940 NDUFB9 NDUFB9 ADRM1 ADRM1 KIF5C KIF5C PIK3CB PIK3CB MAPK12 MAPK12 TUBB2A TUBB2A ITPR3 ITPR3 NDUFS4 NDUFS4 NDUFS8 NDUFS8 PSMD13 PSMD13 SDHB SDHB C8A C8A HSPA8 HSPA8 NDUFS7 NDUFS7 SDHD SDHD VDAC3 VDAC3 ENSMODP00000057502 ENSMODP00000057502 LOC100012494 LOC100012494 GRIN2A GRIN2A CYCS CYCS EGR1 EGR1 CREB1 CREB1 ENSMODP00000059492 ENSMODP00000059492 GSK3B GSK3B ENSMODP00000060103 ENSMODP00000060103 APAF1 APAF1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (77 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
RAC2Rac family small GTPase 2. (281 aa)
LOC100015203Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
NCF4Neutrophil cytosolic factor 4. (340 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (508 aa)
VDAC2Voltage dependent anion channel 2. (283 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
IL6Uncharacterized protein. (220 aa)
NDUFA11Uncharacterized protein. (141 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
LOC100010487Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (928 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (124 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (357 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (112 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (80 aa)
UQCR11Uncharacterized protein. (56 aa)
CYBACytochrome b-245 alpha chain. (191 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (127 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMB6Proteasome subunit beta. (246 aa)
PSMB1Proteasome subunit beta. (244 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1019 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (722 aa)
LOC100030489COX6C domain-containing protein. (75 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
NCF1Neutrophil cytosolic factor 1. (389 aa)
LAMC1Laminin subunit gamma 1. (1486 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NCF2Neutrophil cytosolic factor 2. (528 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
CREB3BZIP domain-containing protein. (370 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (363 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
KLC2TPR_REGION domain-containing protein. (522 aa)
ATF4Activating transcription factor 4. (346 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ATP5MC3ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1104 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (64 aa)
CYC1Cytochrome c1. (320 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (100 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
PSMB3Proteasome subunit beta. (205 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (540 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
LOC100015788Uncharacterized protein. (82 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (518 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
VDAC1Voltage dependent anion channel 1. (400 aa)
GRIN3AUncharacterized protein. (1153 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
LOC100010481Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (504 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
COX5BCytochrome c oxidase subunit 5B. (128 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
C1QCComplement C1q C chain. (245 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa)
ATP5F1EUncharacterized protein. (51 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (420 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (360 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PSMB2Uncharacterized protein. (83 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1463 aa)
NDUFA9Epimerase domain-containing protein. (377 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (157 aa)
F7B3U4_MONDOUncharacterized protein. (108 aa)
KLC4Kinesin light chain 4. (611 aa)
CCL5C-C motif chemokine ligand 5. (91 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (451 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
C5Complement C5. (1638 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
PSMB7Proteasome subunit beta. (277 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (657 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (525 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (437 aa)
NDUFS3Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (539 aa)
C6Complement C6. (933 aa)
C7Complement C7. (836 aa)
C9Complement C9. (620 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
NDUFV3Uncharacterized protein. (421 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (177 aa)
CYBBCytochrome b-245 beta chain. (573 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (195 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NDUFV1NADH:ubiquinone oxidoreductase core subunit V1. (438 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (228 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (116 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (608 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (166 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (382 aa)
H9H824_MONDONADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (114 aa)
H9H9I1_MONDOUncharacterized protein. (82 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
F7BQU1_MONDOCytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (83 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC100024672Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (439 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC100018337Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
LOC100011711Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
LOC100015032Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
LOC100016464Proteasome subunit beta. (183 aa)
F7BFL6_MONDOUncharacterized protein. (88 aa)
F6U2Q2_MONDOUncharacterized protein. (116 aa)
PSMD9Uncharacterized protein. (228 aa)
LOC100026811Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC100032606Uncharacterized protein; Belongs to the peptidase C14A family. (398 aa)
NDUFS5Uncharacterized protein. (171 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (511 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
LOC100026672Uncharacterized protein. (455 aa)
KLC1Uncharacterized protein. (637 aa)
PSMD4VWFA domain-containing protein. (453 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (392 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (938 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1253 aa)
BADUncharacterized protein. (212 aa)
ATP5MC1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (535 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
NDUFA5Uncharacterized protein. (133 aa)
NCAM2Neural cell adhesion molecule 2. (804 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
ENSMODP00000045334Uncharacterized protein. (74 aa)
PRNPMajor prion protein; Belongs to the prion family. (282 aa)
PSMA2Proteasome endopeptidase complex. (313 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
NCAM1Neural cell adhesion molecule 1. (1120 aa)
RYR2Ryanodine receptor 2. (4900 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
LOC100030139Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
PSMC5AAA domain-containing protein; Belongs to the AAA ATPase family. (502 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (480 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
LOC100032604Uncharacterized protein; Belongs to the peptidase C14A family. (428 aa)
NDUFB1Uncharacterized protein. (58 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (279 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (726 aa)
LOC100020481Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (78 aa)
NDUFB4Uncharacterized protein. (127 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
C1QBC1q domain-containing protein. (288 aa)
BAXUncharacterized protein. (296 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
RYR3Ryanodine receptor 3. (4841 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
NDUFA7Uncharacterized protein. (186 aa)
PSMD8PCI domain-containing protein. (283 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (242 aa)
C1QAC1q domain-containing protein. (245 aa)
ENSMODP00000050493Uncharacterized protein. (105 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2123 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (483 aa)
MCUMitochondrial calcium uniporter. (353 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
ENSMODP00000051940Uncharacterized protein. (70 aa)
NDUFB9Uncharacterized protein; Belongs to the complex I LYR family. (249 aa)
ADRM1Adhesion regulating molecule 1. (406 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (992 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa)
NDUFS4Uncharacterized protein. (180 aa)
NDUFS84Fe-4S ferredoxin-type domain-containing protein. (64 aa)
PSMD13Uncharacterized protein. (203 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
C8AComplement C8 alpha chain. (580 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (648 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (215 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
VDAC3Uncharacterized protein. (284 aa)
ENSMODP00000057502Uncharacterized protein. (201 aa)
LOC100012494Cytochrome c oxidase subunit 6A, mitochondrial. (152 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1365 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ENSMODP00000059492Uncharacterized protein. (77 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
ENSMODP00000060103Uncharacterized protein. (92 aa)
APAF1Apoptotic peptidase activating factor 1. (1279 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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