43 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CREB3L3	cAMP responsive element binding protein 3 like 3. (508 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (709 aa)
	GNAI3	G protein subunit alpha i3. (399 aa)
	F7E0E8_MONDO	BH4_AAA_HYDROXYL_2 domain-containing protein. (391 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
	GRIN3B	Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1019 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
	GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
	CREB3	BZIP domain-containing protein. (370 aa)
	DDC	Dopa decarboxylase. (515 aa)
	ATF4	Activating transcription factor 4. (346 aa)
	SLC18A2	Solute carrier family 18 member A2. (514 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (543 aa)
	SLC18A1	Solute carrier family 18 member A1. (526 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (207 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (518 aa)
	PDYN	Prodynorphin. (258 aa)
	GRIN3A	Uncharacterized protein. (1153 aa)
	ATF6B	Activating transcription factor 6 beta. (708 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (504 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (360 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1463 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (995 aa)
	MAOB	Amine oxidase. (520 aa)
	MAOA	Amine oxidase. (553 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (334 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (306 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	GNAI2	G protein subunit alpha i2. (315 aa)
	RGS9	RGS domain-containing protein. (257 aa)
	GRIN1	Glutamate ionotropic receptor NMDA type subunit 1. (938 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (535 aa)
	GRM3	Glutamate metabotropic receptor 3. (889 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (285 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
	GPSM1	Uncharacterized protein. (168 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1365 aa)
	CREB1	cAMP responsive element binding protein 1. (327 aa)
	ENSMODP00000059741	Uncharacterized protein. (70 aa)
	GNAS	Uncharacterized protein. (370 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF4	ENSMODP00000011885	ENSMODP00000011720	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 4.	0.943
ATF2	ATF6B	ENSMODP00000011885	ENSMODP00000018655	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 6 beta.	0.920
ATF2	CREB1	ENSMODP00000011885	ENSMODP00000059251	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 1.	0.966
ATF2	CREB3	ENSMODP00000011885	ENSMODP00000009022	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	BZIP domain-containing protein.	0.916
ATF2	CREB3L1	ENSMODP00000011885	ENSMODP00000044450	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 1.	0.903
ATF2	CREB3L2	ENSMODP00000011885	ENSMODP00000017359	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 2.	0.901
ATF2	CREB3L3	ENSMODP00000011885	ENSMODP00000000973	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 3.	0.906
ATF2	CREB3L4	ENSMODP00000011885	ENSMODP00000021586	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 4.	0.904
ATF2	CREB5	ENSMODP00000011885	ENSMODP00000019151	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.960
ATF2	JUN	ENSMODP00000011885	ENSMODP00000004058	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.998
ATF2	PRKACA	ENSMODP00000011885	ENSMODP00000048595	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.918
ATF4	ATF2	ENSMODP00000011720	ENSMODP00000011885	Activating transcription factor 4.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.943
ATF4	ATF6B	ENSMODP00000011720	ENSMODP00000018655	Activating transcription factor 4.	Activating transcription factor 6 beta.	0.951
ATF4	CREB1	ENSMODP00000011720	ENSMODP00000059251	Activating transcription factor 4.	cAMP responsive element binding protein 1.	0.934
ATF4	CREB3	ENSMODP00000011720	ENSMODP00000009022	Activating transcription factor 4.	BZIP domain-containing protein.	0.909
ATF4	CREB3L1	ENSMODP00000011720	ENSMODP00000044450	Activating transcription factor 4.	cAMP responsive element binding protein 3 like 1.	0.906
ATF4	CREB3L2	ENSMODP00000011720	ENSMODP00000017359	Activating transcription factor 4.	cAMP responsive element binding protein 3 like 2.	0.906
ATF4	CREB3L3	ENSMODP00000011720	ENSMODP00000000973	Activating transcription factor 4.	cAMP responsive element binding protein 3 like 3.	0.910
ATF4	CREB3L4	ENSMODP00000011720	ENSMODP00000021586	Activating transcription factor 4.	cAMP responsive element binding protein 3 like 4.	0.906
ATF4	CREB5	ENSMODP00000011720	ENSMODP00000019151	Activating transcription factor 4.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.938