STRINGSTRING
SRC SRC ARPC1A ARPC1A ARPC1B ARPC1B SEPTIN9 SEPTIN9 PIK3R3 PIK3R3 SHC4 SHC4 CLTA CLTA CDH1 CDH1 ARPC4 ARPC4 CLTB CLTB ELMO3 ELMO3 SEPTIN12 SEPTIN12 F6PU44_MONDO F6PU44_MONDO ARPC5 ARPC5 CLTCL1 CLTCL1 SEPTIN5 SEPTIN5 SEPTIN6 SEPTIN6 MAD2L2 MAD2L2 CTNNB1 CTNNB1 F6U132_MONDO F6U132_MONDO LOC100028958 LOC100028958 CTNNA1 CTNNA1 CBL CBL SHC3 SHC3 SEPTIN8 SEPTIN8 WASL WASL ARPC2 ARPC2 MET MET CAV1 CAV1 ARHGEF26 ARHGEF26 SHC1 SHC1 CTNNA3 CTNNA3 CRKL CRKL PIK3R1 PIK3R1 ARPC5L ARPC5L PIK3CA PIK3CA LOC100016601 LOC100016601 ELMO2 ELMO2 WASF2 WASF2 CDC42 CDC42 RHOG RHOG F7CI75_MONDO F7CI75_MONDO ARHGAP10 ARHGAP10 LOC100020439 LOC100020439 HCLS1 HCLS1 ELMO1 ELMO1 ITGB1 ITGB1 CLTC CLTC SEPT1 SEPT1 CAV2 CAV2 ACTG1 ACTG1 FN1 FN1 ILK ILK VCL VCL CAV3 CAV3 DNM2 DNM2 PTK2 PTK2 PIK3CB PIK3CB CTNNA2 CTNNA2 SEPTIN11 SEPTIN11 DNM3 DNM3 RHOA RHOA DNM1 DNM1 GAB1 GAB1 CD2AP CD2AP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (550 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (367 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (572 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
SHC4SHC adaptor protein 4. (678 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
ELMO3Engulfment and cell motility 3. (720 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (356 aa)
F6PU44_MONDODHR-2 domain-containing protein; Belongs to the DOCK family. (930 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (304 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1556 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (350 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (351 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (223 aa)
CTNNB1Catenin beta 1. (781 aa)
F6U132_MONDOActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
LOC100028958Uncharacterized protein. (375 aa)
CTNNA1Uncharacterized protein. (906 aa)
CBLCbl proto-oncogene. (837 aa)
SHC3SHC adaptor protein 3. (602 aa)
SEPTIN8Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (369 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (330 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1387 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (877 aa)
SHC1SHC adaptor protein 1. (577 aa)
CTNNA3Uncharacterized protein. (454 aa)
CRKLUncharacterized protein. (303 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (158 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100016601Uncharacterized protein. (374 aa)
ELMO2Engulfment and cell motility 2. (742 aa)
WASF2WASP family member 2. (497 aa)
CDC42Cell division cycle 42. (191 aa)
RHOGRas homolog family member G. (191 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
ARHGAP10Rho GTPase activating protein 10. (785 aa)
LOC100020439Uncharacterized protein; Belongs to the actin family. (374 aa)
HCLS1SH3 domain-containing protein. (408 aa)
ELMO1PH domain-containing protein. (144 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
SEPT1Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (85 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ACTG1Uncharacterized protein. (375 aa)
FN1Fibronectin 1. (2482 aa)
ILKIntegrin linked kinase. (486 aa)
VCLVinculin. (1147 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (242 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (881 aa)
PTK2Uncharacterized protein. (161 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
CTNNA2Uncharacterized protein. (651 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (440 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (955 aa)
RHOAUncharacterized protein. (193 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (937 aa)
GAB1GRB2 associated binding protein 1. (743 aa)
CD2APCD2 associated protein. (733 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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