46 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL6	Uncharacterized protein. (220 aa)
	C3	Complement C3. (1641 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1076 aa)
	RAB1A	RAB1A, member RAS oncogene family. (185 aa)
	CLK4	CDC like kinase 4. (507 aa)
	CASP3	Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
	HSPA1A	Uncharacterized protein; Belongs to the heat shock protein 70 family. (722 aa)
	LOC100009907	Uncharacterized protein. (438 aa)
	EEF1G	Uncharacterized protein. (438 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	RAB1B	RAB1B, member RAS oncogene family. (201 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (543 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
	HSPD1	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
	ARF1	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (179 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
	CLK1	CDC like kinase 1; Belongs to the protein kinase superfamily. (487 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (472 aa)
	EEF1A2	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (437 aa)
	HBS1L	GTP_EFTU_D3 domain-containing protein. (172 aa)
	BCL2L13	BCL2 like 13. (467 aa)
	SEC22B	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (216 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	BNIP3	BCL2 interacting protein 3. (195 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (995 aa)
	CD14	Uncharacterized protein. (382 aa)
	F7G5T5_MONDO	Uncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
	LOC100032592	Uncharacterized protein; Belongs to the peptidase C14A family. (375 aa)
	TLR5	Toll like receptor 5; Belongs to the Toll-like receptor family. (861 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
	LOC100011711	Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
	LOC100015032	Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	CASP18	Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
	LOC100026811	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	ITGB2	Integrin beta. (792 aa)
	LOC654275	Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
	LOC103102395	Uncharacterized protein. (207 aa)
	NFKBIA	ANK_REP_REGION domain-containing protein. (400 aa)
	HSPA8	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (648 aa)
	CYCS	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	ITGAM-2	VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1177 aa)
	LOC103101367	Uncharacterized protein. (211 aa)
	APAF1	Apoptotic peptidase activating factor 1. (1279 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	CASP18	ENSMODP00000060445	ENSMODP00000040167	Apoptotic peptidase activating factor 1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.788
APAF1	CASP3	ENSMODP00000060445	ENSMODP00000005560	Apoptotic peptidase activating factor 1.	Caspase-3-like protein 1; Belongs to the peptidase C14A family.	0.982
APAF1	CASP8	ENSMODP00000060445	ENSMODP00000018969	Apoptotic peptidase activating factor 1.	Caspase 8; Belongs to the peptidase C14A family.	0.778
APAF1	CYCS	ENSMODP00000060445	ENSMODP00000058499	Apoptotic peptidase activating factor 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APAF1	EEF1G	ENSMODP00000060445	ENSMODP00000009556	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.512
APAF1	F7G5T5_MONDO	ENSMODP00000060445	ENSMODP00000034020	Apoptotic peptidase activating factor 1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.642
APAF1	HBS1L	ENSMODP00000060445	ENSMODP00000021834	Apoptotic peptidase activating factor 1.	GTP_EFTU_D3 domain-containing protein.	0.509
APAF1	LOC100009907	ENSMODP00000060445	ENSMODP00000009552	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.512
APAF1	LOC100026811	ENSMODP00000060445	ENSMODP00000041124	Apoptotic peptidase activating factor 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APAF1	LOC100032592	ENSMODP00000060445	ENSMODP00000034022	Apoptotic peptidase activating factor 1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.642
APAF1	LOC654275	ENSMODP00000060445	ENSMODP00000046868	Apoptotic peptidase activating factor 1.	Caspase-3-like protein 2; Belongs to the peptidase C14A family.	0.978
ARF1	RAB1A	ENSMODP00000017256	ENSMODP00000004085	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB1A, member RAS oncogene family.	0.406
ARF1	RAB1B	ENSMODP00000017256	ENSMODP00000010405	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB1B, member RAS oncogene family.	0.406
ARF1	SEC22B	ENSMODP00000017256	ENSMODP00000023317	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.	0.488
BCL2L13	BNIP3	ENSMODP00000023011	ENSMODP00000024552	BCL2 like 13.	BCL2 interacting protein 3.	0.519
BNIP3	BCL2L13	ENSMODP00000024552	ENSMODP00000023011	BCL2 interacting protein 3.	BCL2 like 13.	0.519
BNIP3	IL1B	ENSMODP00000024552	ENSMODP00000017267	BCL2 interacting protein 3.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.465
BNIP3	TLR4	ENSMODP00000024552	ENSMODP00000024473	BCL2 interacting protein 3.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.404
C3	ITGAM	ENSMODP00000002605	ENSMODP00000003070	Complement C3.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.928
C3	ITGAM-2	ENSMODP00000002605	ENSMODP00000058520	Complement C3.	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	0.928