STRINGSTRING
SRC SRC ACTR3 ACTR3 PLCG1 PLCG1 RAC2 RAC2 TICAM1 TICAM1 IL6 IL6 IL10 IL10 PIK3R3 PIK3R3 PKN1 PKN1 PIP5K1B PIP5K1B RAC3 RAC3 JUN JUN ACTR2 ACTR2 ZAP70 ZAP70 GIT2 GIT2 ACTR3B ACTR3B FOS FOS MAP2K6 MAP2K6 AKT3 AKT3 LCP2 LCP2 F6PU44_MONDO F6PU44_MONDO AKT2 AKT2 RPS6KA3 RPS6KA3 IKBKG IKBKG TAB1 TAB1 CD8A CD8A CD8B CD8B RELA RELA MAP2K1 MAP2K1 IKBKB IKBKB WAS WAS ITGA4 ITGA4 CHUK CHUK LOC100028958 LOC100028958 GNAQ GNAQ WIPF2 WIPF2 ARHGEF12 ARHGEF12 IRF3 IRF3 MAPK13 MAPK13 AKT1 AKT1 IL1B IL1B LIMK1 LIMK1 RPS6KA6 RPS6KA6 MAP2K7 MAP2K7 WASL WASL MAPK3 MAPK3 MEFV MEFV TRAF2 TRAF2 LCK LCK CRKL CRKL MAPK1 MAPK1 IRAK4 IRAK4 PIP5K1A PIP5K1A LOC103093665 LOC103093665 CXCL8 CXCL8 TLR4 TLR4 PIK3R1 PIK3R1 TRAF6 TRAF6 FYB1 FYB1 NFKB1 NFKB1 MAPK10 MAPK10 PIK3CA PIK3CA LOC100016601 LOC100016601 ELMO2 ELMO2 MAPK9 MAPK9 ARF6 ARF6 WASF2 WASF2 CDC42 CDC42 RHOG RHOG VAV1 VAV1 F7CI75_MONDO F7CI75_MONDO F7G5T5_MONDO F7G5T5_MONDO LOC100032592 LOC100032592 CD4 CD4 LOC100020439 LOC100020439 LOC100021258 LOC100021258 PYCARD PYCARD K7DYV5_MONDO K7DYV5_MONDO ELMO1 ELMO1 ITGB1 ITGB1 MAP2K3 MAP2K3 WIPF1 WIPF1 NFATC3 NFATC3 BAIAP2 BAIAP2 ACTG1 ACTG1 RPS6KA2 RPS6KA2 SKAP2 SKAP2 RPS6KA1 RPS6KA1 NFATC1 NFATC1 FN1 FN1 MAP3K7 MAP3K7 MAPK14 MAPK14 PKN2 PKN2 NFATC2 NFATC2 LOC103102395 LOC103102395 IL2 IL2 ARHGEF7 ARHGEF7 PTK2 PTK2 ARHGEF28 ARHGEF28 PIK3CB PIK3CB MAPK12 MAPK12 VAV3 VAV3 TAB2 TAB2 NFKBIA NFKBIA F7BIP4_MONDO F7BIP4_MONDO WIPF3 WIPF3 ROCK1 ROCK1 SIRT6 SIRT6 RHOA RHOA LOC103101367 LOC103101367 GSK3B GSK3B ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (550 aa)
ACTR3Uncharacterized protein; Belongs to the actin family. (569 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
RAC2Rac family small GTPase 2. (281 aa)
TICAM1TRIF-NTD domain-containing protein. (713 aa)
IL6Uncharacterized protein. (220 aa)
IL10Interleukin 10. (173 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
PKN1Protein kinase N1. (956 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (556 aa)
RAC3Rac family small GTPase 3. (192 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
GIT2GIT ArfGAP 2. (770 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (418 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LCP2SH2 domain-containing protein. (319 aa)
F6PU44_MONDODHR-2 domain-containing protein; Belongs to the DOCK family. (930 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (652 aa)
CD8AIg-like domain-containing protein. (340 aa)
CD8BIg-like domain-containing protein. (215 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
WASWASP actin nucleation promoting factor. (504 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
LOC100028958Uncharacterized protein. (375 aa)
GNAQG protein subunit alpha q. (359 aa)
WIPF2WAS/WASL interacting protein family member 2. (443 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1539 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (409 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
LIMK1LIM domain kinase 1. (602 aa)
RPS6KA6Ribosomal protein S6 kinase. (771 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
MEFVUncharacterized protein. (793 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
LCKTyrosine-protein kinase. (686 aa)
CRKLUncharacterized protein. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
PIP5K1APIPK domain-containing protein. (630 aa)
LOC103093665C-C motif chemokine. (226 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
FYB1FYN binding protein 1. (851 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100016601Uncharacterized protein. (374 aa)
ELMO2Engulfment and cell motility 2. (742 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
WASF2WASP family member 2. (497 aa)
CDC42Cell division cycle 42. (191 aa)
RHOGRas homolog family member G. (191 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
F7G5T5_MONDOUncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
LOC100032592Uncharacterized protein; Belongs to the peptidase C14A family. (375 aa)
CD4CD4. (461 aa)
LOC100020439Uncharacterized protein; Belongs to the actin family. (374 aa)
LOC100021258Type I interferon 1. (198 aa)
PYCARDPYD and CARD domain containing. (195 aa)
K7DYV5_MONDOIg-like domain-containing protein. (295 aa)
ELMO1PH domain-containing protein. (144 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
MAP2K3Mitogen-activated protein kinase kinase 3. (239 aa)
WIPF1WAS/WASL interacting protein family member 1. (513 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
ACTG1Uncharacterized protein. (375 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
SKAP2Src kinase associated phosphoprotein 2. (419 aa)
RPS6KA1Ribosomal protein S6 kinase. (740 aa)
NFATC1Nuclear factor of activated T cells 1. (950 aa)
FN1Fibronectin 1. (2482 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PKN2Protein kinase N2. (1013 aa)
NFATC2Nuclear factor of activated T cells 2. (927 aa)
LOC103102395Uncharacterized protein. (207 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (869 aa)
PTK2Uncharacterized protein. (161 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1784 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
F7BIP4_MONDOIg-like domain-containing protein. (182 aa)
WIPF3WH2 domain-containing protein. (352 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
SIRT6Uncharacterized protein. (547 aa)
RHOAUncharacterized protein. (193 aa)
LOC103101367Uncharacterized protein. (211 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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